Oxidation by cytochrome P450 (WP1274)

Mus musculus

Oxidation of a substrate by Cytochrome P450. Adapted from Niesink et al., Chapter 3, p. 47-48.

Authors

Christine Chichester , Kristina Hanspers , Eric Weitz , Alex Pico , and Lars Willighagen

Activity

last edited

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Cited In

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Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

phase I biotransformation pathway via cytochrome P450

Participants

Label Type Compact URI Comment
NADPH Metabolite chebi:16474
O2 Metabolite hmdb:HMDB0001377
Fe3+ Metabolite chebi:29034
Water Metabolite hmdb:HMDB0002111
NADP+ Metabolite chebi:18009
Fe2+ Metabolite chebi:29033
NADH Metabolite chebi:16908
NAD+ Metabolite chebi:15846
Cyp26a1 GeneProduct ensembl:ENSMUSG00000024987
Cyb5b GeneProduct ensembl:ENSMUSG00000031924
Cyb5r1 GeneProduct ensembl:ENSMUSG00000026456
Cyp4f39 GeneProduct ensembl:ENSMUSG00000061126
Cyb5 GeneProduct ensembl:ENSMUSG00000024646
Cyp1b1 GeneProduct ensembl:ENSMUSG00000024087
Cyb5r4 GeneProduct ensembl:ENSMUSG00000032872
Cyb5r2 GeneProduct ensembl:ENSMUSG00000048065
Cyp11b1 GeneProduct ncbigene:110115
Cyp27b1 GeneProduct ensembl:ENSMUSG00000006724
Cyp4f18 GeneProduct ensembl:ENSMUSG00000003484
Cyp26c1 GeneProduct ensembl:ENSMUSG00000062432
Cyp51 GeneProduct ensembl:ENSMUSG00000001467
Cyp7b1 GeneProduct ensembl:ENSMUSG00000039519
Cyp19a1 GeneProduct ensembl:ENSMUSG00000032274
Cyp21a1 GeneProduct ensembl:ENSMUSG00000024365
Cyp26b1 GeneProduct ensembl:ENSMUSG00000063415
Cyp7a1 GeneProduct ensembl:ENSMUSG00000028240
AC161058.2-1 GeneProduct ensembl:ENSMUSG00000029541
Cyp8b1 GeneProduct ensembl:ENSMUSG00000050445
Cyp2s1 GeneProduct ensembl:ENSMUSG00000040703
Cyp39a1 GeneProduct ensembl:ENSMUSG00000023963
Cyp2r1 GeneProduct ensembl:ENSMUSG00000030670
Cyp46a1 GeneProduct ensembl:ENSMUSG00000021259
Cyp4b1 GeneProduct ensembl:ENSMUSG00000028713
Cyp1a2 GeneProduct ensembl:ENSMUSG00000032310
Cyp4v3 GeneProduct ensembl:ENSMUSG00000079057
Cyp2u1 GeneProduct ensembl:ENSMUSG00000027983
Cyp4x1 GeneProduct ensembl:ENSMUSG00000047155
Cyp2e1 GeneProduct ensembl:ENSMUSG00000025479
Cyp11a1 GeneProduct ensembl:ENSMUSG00000032323
Cyp20a1 GeneProduct ensembl:ENSMUSG00000049439
Por GeneProduct ensembl:ENSMUSG00000005514
Cyp17a1 GeneProduct ensembl:ENSMUSG00000003555
Cyp27a1 GeneProduct ensembl:ENSMUSG00000026170
Cyp2f2 GeneProduct ensembl:ENSMUSG00000052974
Cyb5r3 GeneProduct ensembl:ENSMUSG00000018042
Cyp11b2 GeneProduct ncbigene:13072
Cyp24a1 GeneProduct ensembl:ENSMUSG00000038567
Cyp1a1 GeneProduct ensembl:ENSMUSG00000032315

References

  1. Toxicology [Internet]. Niesink R, Hollinger MA, De Vries J. CRC Press; 1996. 1312 p. Available from: https://books.google.com/books/about/Toxicology.html?hl=&id=mwN9QgAACAAJ OpenLibrary Worldcat