Adipogenesis (WP987)
Bos taurus
The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.
Authors
Kristina Hanspers and Martina Summer-KutmonActivity
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Cited In
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Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
signaling pathway pertinent to development| Label | Type | Compact URI | Comment |
|---|---|---|---|
| IGF-I | GeneProduct | ensembl:ENSBTAG00000011082 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3479 |
| PTGIS | GeneProduct | ensembl:ENSBTAG00000017537 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5740 |
| PPARD | GeneProduct | ensembl:ENSBTAG00000017542 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5467 |
| CREB1 | GeneProduct | ensembl:ENSBTAG00000005474 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1385 |
| MIXL1 | GeneProduct | ensembl:ENSBTAG00000002139 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:83881 |
| ID3 | GeneProduct | ensembl:ENSBTAG00000030425 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3399 |
| WNT10B | GeneProduct | ensembl:ENSBTAG00000015347 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7480 |
| STAT5A | GeneProduct | ensembl:ENSBTAG00000009496 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6776 |
| STAT5B | GeneProduct | ensembl:ENSBTAG00000010125 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6777 |
| DLK | GeneProduct | ensembl:ENSBTAG00000037899 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8788 |
| GR-A | GeneProduct | ensembl:ENSBTAG00000019472 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2908 |
| DDIT3 | GeneProduct | ensembl:ENSBTAG00000031544 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1649 |
| LIF | GeneProduct | ensembl:ENSBTAG00000007424 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3976 |
| CYP26A1 | GeneProduct | ensembl:ENSBTAG00000021118 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1592 |
| CYP26B1 | GeneProduct | ensembl:ENSBTAG00000012212 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:56603 |
| RXRA | GeneProduct | ensembl:ENSBTAG00000017851 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6256 |
| RARA | GeneProduct | ensembl:ENSBTAG00000012500 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5914 |
| NR1H3 | GeneProduct | ensembl:ENSBTAG00000010681 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10062 |
| LPL | GeneProduct | ensembl:ENSBTAG00000012855 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4023 |
| SREBF1 | GeneProduct | ensembl:ENSBTAG00000007884 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6720 |
| FAS | GeneProduct | ensembl:ENSBTAG00000010785 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:355 |
| RBL1 | GeneProduct | ensembl:ENSBTAG00000011541 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5933 |
| GATA3 | GeneProduct | ensembl:ENSBTAG00000017243 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2625 |
| GATA2 | GeneProduct | ensembl:ENSBTAG00000019707 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2624 |
| PPARG | GeneProduct | ensembl:ENSBTAG00000001333 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5468 |
| MEF2A | GeneProduct | ensembl:ENSBTAG00000010649 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4205 |
| MEF2C | GeneProduct | ensembl:ENSBTAG00000020701 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4208 |
| MEF2D | GeneProduct | ensembl:ENSBTAG00000046545 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4209 |
| ASIP | GeneProduct | ensembl:ENSBTAG00000034077 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:434 |
| TNF | GeneProduct | ensembl:ENSBTAG00000025471 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7124 |
| MIF | GeneProduct | ensembl:ENSBTAG00000007375 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4282 |
| TGFB1 | GeneProduct | ensembl:ENSBTAG00000020457 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7040 |
| SERPINE1 | GeneProduct | ensembl:ENSBTAG00000014465 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5054 |
| SLC2A4 | GeneProduct | ensembl:ENSBTAG00000009190 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6517 |
| SCD | GeneProduct | ensembl:ENSBTAG00000047957 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6319 |
| TWIST1 | GeneProduct | ensembl:ENSBTAG00000046922 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7291 |
| OB | GeneProduct | ensembl:ENSBTAG00000014911 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3952 |
| RETN | GeneProduct | ensembl:ENSBTAG00000004716 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:56729 |
| DF | GeneProduct | ensembl:ENSBTAG00000046245 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1675 |
| GTF3A | GeneProduct | ensembl:ENSBTAG00000012600 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2971 |
| RB1 | GeneProduct | ensembl:ENSBTAG00000006640 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5925 |
| RBL2 | GeneProduct | ensembl:ENSBTAG00000016243 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5934 |
| ADIPOQ | GeneProduct | ensembl:ENSBTAG00000019813 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9370 |
| PLIN2 | GeneProduct | ensembl:ENSBTAG00000005718 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:123 |
| AGT | GeneProduct | ensembl:ENSBTAG00000012393 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:183 |
| CDKN1A | GeneProduct | ensembl:ENSBTAG00000008353 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1026 |
| E2F1 | GeneProduct | ensembl:ENSBTAG00000003971 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1869 |
| SP1 | GeneProduct | ensembl:ENSBTAG00000003021 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6667 |
| HMGA1 | GeneProduct | ensembl:ENSBTAG00000034529 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3159 |
| PLIN | GeneProduct | ensembl:ENSBTAG00000015350 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5346 |
| IL6 | GeneProduct | ensembl:ENSBTAG00000014921 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3569 |
| GADD45A | GeneProduct | ensembl:ENSBTAG00000013860 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1647 |
| GADD45B | GeneProduct | ensembl:ENSBTAG00000025462 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4616 |
| BMP1 | GeneProduct | ensembl:ENSBTAG00000000917 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:649 |
| BMP2 | GeneProduct | ensembl:ENSBTAG00000005111 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:650 |
| BMP3 | GeneProduct | ensembl:ENSBTAG00000017642 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:651 |
| BMP4 | GeneProduct | ensembl:ENSBTAG00000003835 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:652 |
| NDN | GeneProduct | ensembl:ENSBTAG00000002186 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4692 |
| FOXO1 | GeneProduct | ensembl:ENSBTAG00000044105 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2308 |
| KLF5 | GeneProduct | ensembl:ENSBTAG00000002129 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:688 |
| FOXC2 | GeneProduct | ensembl:ENSBTAG00000012465 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2303 |
| PPARGC1A | GeneProduct | ensembl:ENSBTAG00000017024 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10891 |
| NCOA1 | GeneProduct | ensembl:ENSBTAG00000015007 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8648 |
| NCOA2 | GeneProduct | ensembl:ENSBTAG00000020312 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10499 |
| PPARA | GeneProduct | ensembl:ENSBTAG00000008063 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5465 |
| STAT3 | GeneProduct | ensembl:ENSBTAG00000021523 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6774 |
| STAT2 | GeneProduct | ensembl:ENSBTAG00000004380 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6773 |
| STAT1 | GeneProduct | ensembl:ENSBTAG00000007867 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6772 |
| STAT6 | GeneProduct | ensembl:ENSBTAG00000006335 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6778 |
| SOCS1 | GeneProduct | ensembl:ENSBTAG00000004386 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8651 |
| SOCS3 | GeneProduct | ensembl:ENSBTAG00000008441 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9021 |
| CNTFR | GeneProduct | ensembl:ENSBTAG00000015361 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1271 |
| LIFR | GeneProduct | ensembl:ENSBTAG00000010423 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3977 |
| IL6ST | GeneProduct | ensembl:ENSBTAG00000017745 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3572 |
| MBNL1 | GeneProduct | ensembl:ENSBTAG00000004564 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4154 |
| OSM | GeneProduct | ensembl:ENSBTAG00000016163 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5008 |
| CTNNB1 | GeneProduct | ensembl:ENSBTAG00000016420 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1499 |
| UCP1 | GeneProduct | ensembl:ENSBTAG00000004647 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7350 |
| WNT5B | GeneProduct | ensembl:ENSBTAG00000001341 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:81029 |
| WNT1 | GeneProduct | ensembl:ENSBTAG00000015364 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7471 |
| SMAD3 | GeneProduct | ensembl:ENSBTAG00000012599 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4088 |
| FZD1 | GeneProduct | ensembl:ENSBTAG00000002107 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8321 |
| DVL1 | GeneProduct | ensembl:ENSBTAG00000010696 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1855 |
| HNF1A | GeneProduct | ensembl:ENSBTAG00000021795 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6927 |
| RXRG | GeneProduct | ensembl:ENSBTAG00000016801 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6258 |
| FRZB | GeneProduct | ensembl:ENSBTAG00000010977 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2487 |
| NAMPT | GeneProduct | ensembl:ENSBTAG00000015509 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10135 |
| SPOCK1 | GeneProduct | ensembl:ENSBTAG00000003502 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6695 |
| TRIB3 | GeneProduct | ensembl:ENSBTAG00000017007 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:57761 |
| GATA4 | GeneProduct | ensembl:ENSBTAG00000005425 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2626 |
| NR2F1 | GeneProduct | ensembl:ENSBTAG00000017599 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7025 |
| NRIP1 | GeneProduct | ensembl:ENSBTAG00000047293 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8204 |
| RORA | GeneProduct | ensembl:ENSBTAG00000015904 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6095 |
| PRLR | GeneProduct | ensembl:ENSBTAG00000025035 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5618 |
| ADPN | GeneProduct | ensembl:ENSBTAG00000045746 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:80339 |
| CUGBP1 | GeneProduct | ensembl:ENSBTAG00000002520 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10658 |
| HIF1A | GeneProduct | ensembl:ENSBTAG00000020935 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3091 |
| KLF6 | GeneProduct | ensembl:ENSBTAG00000015188 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1316 |
| KLF7 | GeneProduct | ensembl:ENSBTAG00000044097 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8609 |
| SFRP4 | GeneProduct | ensembl:ENSBTAG00000015366 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6424 |
| NCOR1 | GeneProduct | ensembl:ENSBTAG00000013271 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9611 |
| NCOR2 | GeneProduct | ensembl:ENSBTAG00000024603 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9612 |
| KLF15 | GeneProduct | ensembl:ENSBTAG00000008313 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:28999 |
| EGR2 | GeneProduct | ensembl:ENSBTAG00000046409 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1959 |
| EBF1 | GeneProduct | ensembl:ENSBTAG00000037508 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1879 |
| EPAS1 | GeneProduct | ensembl:ENSBTAG00000003711 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2034 |
| AHR | GeneProduct | ensembl:ENSBTAG00000007746 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:196 |
| CISD1 | GeneProduct | ensembl:ENSBTAG00000003634 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55847 |
| WWTR1 | GeneProduct | ensembl:ENSBTAG00000007814 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:25937 |
| GDF10 | GeneProduct | ensembl:ENSBTAG00000001019 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2662 |
| IRS1 | GeneProduct | ensembl:ENSBTAG00000021308 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3667 |
| IRS4 | GeneProduct | ensembl:ENSBTAG00000006535 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8471 |
| BSCL2 | GeneProduct | ensembl:ENSBTAG00000002503 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26580 |
| LMNA | GeneProduct | ensembl:ENSBTAG00000017574 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4000 |
| AGPAT2 | GeneProduct | ensembl:ENSBTAG00000025161 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10555 |
| ZMPSTE24 | GeneProduct | ensembl:ENSBTAG00000044178 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10269 |
| LPIN1 | GeneProduct | ensembl:ENSBTAG00000007689 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23175 |
| LPIN2 | GeneProduct | ensembl:ENSBTAG00000012060 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9663 |
| HSL | GeneProduct | ensembl:ENSBTAG00000038321 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3991 |
| PCK1 | GeneProduct | ensembl:ENSBTAG00000001936 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5105 |
| PCK2 | GeneProduct | ensembl:ENSBTAG00000011934 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5106 |
| IRS2 | GeneProduct | ensembl:ENSBTAG00000012019 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8660 |
| LPIN3 | GeneProduct | ensembl:ENSBTAG00000009165 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:64900 |
| E2F4 | GeneProduct | ensembl:ENSBTAG00000012063 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1874 |
References
- Molecular regulation of adipogenesis. Rosen ED, Spiegelman BM. Annu Rev Cell Dev Biol. 2000;16:145–71. PubMed Europe PMC Scholia