Microglia pathogen phagocytosis pathway (WP3937)

Homo sapiens

Authors

Kristina Hanspers , Denise Slenter , Eric Weitz , Daniela Digles , and Alex Pico

Activity

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Cited In

• DNA methylation of ARHGAP30 is negatively associated with ARHGAP30 expression in lung adenocarcinoma, which reduces tumor immunity and is detrimental to patient survival (2021).
• Clinical improvement of DM1 patients reflected by reversal of disease-induced gene expression in blood (2022).
• Discovering Common Pathogenic Mechanisms of COVID-19 and Parkinson Disease: An Integrated Bioinformatics Analysis (2022).

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

Alzheimer's disease pathway innate immune response pathway

Cell Type Ontology

microglial cell

References

1. Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease. Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, et al. Cell. 2013 Apr 25;153(3):707–20. PubMed Europe PMC Scholia