Biosynthesis of aldosterone and cortisol (WP508)

Rattus norvegicus

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Keywords: 17-oh aldosterone biochemistry biosynthesis corticosterone cortisol metabolism metabolism of pregnenolone progesterone steroid

Authors

Thomas Kelder , Kristina Hanspers , Christine Chichester , and Eric Weitz

Activity

last edited

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Organisms

Rattus norvegicus

Communities

Annotations

Pathway Ontology

C21-steroid hormone biosynthetic pathway

Participants

Label Type Compact URI Comment
Cortisol Metabolite hmdb:HMDB0000063
18-OH Corticosterone Metabolite pubchem.compound:11222
Pregnenolone Metabolite chebi:16581
Progesterone Metabolite chebi:17026
17-OH Pregnenolone Metabolite pubchem.compound:91451
Corticosterone Metabolite hmdb:HMDB0001547
Cholesterol Metabolite chebi:16113
Aldosterone Metabolite hmdb:HMDB0000037
11-deoxycortisol Metabolite hmdb:HMDB0000015
Deoxy-corticosterone Metabolite chebi:16973
Hsd3b1 GeneProduct ensembl:ENSRNOG00000019441
Cyp17a1 GeneProduct ensembl:ENSRNOG00000020035
Cyp11b1 GeneProduct ensembl:ENSRNOG00000037385
Cyp11b2 GeneProduct ensembl:ENSRNOG00000030111
Cyp11a1 GeneProduct ensembl:ENSRNOG00000008074
Cyp21a1 GeneProduct ensembl:ENSRNOG00000000428

References