AlexanderPico

Sulfur degradation

Aerobic glycolysis

Aerobic glycolysis - augmented

Sudden infant death syndrome (SIDS) susceptibility pathways

Glucose metabolism in triple-negative breast cancer cells

Lipids measured in liver metastasis from breast cancer

Wnt signaling in kidney disease

PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer

MicroRNA for targeting cancer growth and vascularization in glioblastoma

Mecp2 and associated Rett syndrome

Interferon type I signaling pathways

Cytokines and inflammatory response

Extrafollicular and follicular B cell activation by SARS-CoV-2

Markers of kidney cell lineage

mRNA vaccine activation of dendritic cell and induction of IFN-1

T-cell activation SARS-CoV-2

Poly(glycerol phosphate) wall teichoic acid biosynthesis

Hematopoietic stem cell differentiation

Glial cell differentiation

Mitochondrial complex inhibition leading to liver injury

Gastric acid production

Dengue-2 interactions with complement and coagulation cascades

Downregulation of ACE2 by SARS-CoV-2 spike protein

Physiological and pathological hypertrophy of the heart

15q25 copy number variation

TCA cycle (aka Krebs or citric acid cycle)

Oxidative stress response

Steroid biosynthesis

Glutathione metabolism

Ciliopathies

Endochondral ossification

Envelope proteins and their potential roles in EDMD physiopathology

DNA damage response

Wnt/Beta-catenin signaling inhibitors in current and past clinical trials

GNAQ pathways in port-wine stain

10q11.21q11.23 copy number variation syndrome

Type 2 papillary renal cell carcinoma

Epithelial to mesenchymal transition in colorectal cancer

Liver steatosis adverse outcome pathway

Photodynamic therapy-induced NF-kB survival signaling

Effects of nitric oxide

Vitamin A and carotenoid metabolism

N-glycan biosynthesis

DNA replication

Flowering time pathway

Oxytocin signaling

Flowering time pathway

One-carbon metabolism

Thyroxine (thyroid hormone) production

Estrogen signaling pathway

GABA receptor signaling

Host-pathogen interaction of human coronaviruses - interferon induction

TCA cycle nutrient use and invasiveness of ovarian cancer

Irinotecan pathway

Angiotensin II receptor type 1 pathway

Evolocumab mechanism to reduce LDL cholesterol

4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression

Regulation of apoptosis by parathyroid hormone-related protein

Vitamin D metabolism

Endometrial cancer

ACE inhibitor pathway

7-oxo-C and 7-beta-HC pathways

Angiogenesis

Oxysterols derived from cholesterol

NAD metabolism, sirtuins and aging

Selenium metabolism and selenoproteins

Glioblastoma signaling pathways

Macrophage-stimulating protein (MSP) signaling network map

IL-10 anti-inflammatory signaling pathway

FTO obesity variant mechanism

Gene regulatory network modeling somitogenesis

Histone modifications

Biotin metabolism

Type II diabetes mellitus

Chronic hyperglycemia impairment of neuron function

Parkinson's disease pathway

HDAC6 interactions in the central nervous system

Ether lipid biosynthesis

Hippo-Merlin signaling dysregulation

MECP2 and associated Rett syndrome

Complement activation

Mitochondrial fatty acid oxidation disorders

Apoptosis

Codeine and morphine metabolism

Angiopoietin-like protein 8 regulatory pathway

BDNF-TrkB signaling

ATM signaling pathway

Amyotrophic lateral sclerosis (ALS)

Cholesterol biosynthesis pathway

Apoptosis modulation and signaling

AMP-activated protein kinase signaling

Fructose and mannose metabolism

KCNQ2-related epilepsies

Glycolysis and gluconeogenesis

Activation of NLRP3 inflammasome by SARS-CoV-2

Hippo signaling regulation pathways

PCSK9-mediated LDL receptor degradation

Alzheimer's disease and miRNA effects

Nucleotide GPCRs

Tryptophan metabolism

Toll-like receptor signaling pathway

Monoamine GPCRs

Estradiol regulation in porto-sinusoidal vascular disease

Regulation of actin cytoskeleton

Hedgehog signaling pathway

G1 to S cell cycle control

G protein signaling pathways

Ovarian infertility

Notch signaling pathway

Peptide GPCRs

Statin pathway

T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection

MYD88 distinct input-output pathway

Canonical and non-canonical Notch signaling

p53 transcriptional gene network

EV release from cardiac cells and their functional effects

Androgen receptor network in prostate cancer

Metapathway biotransformation Phase I and II

Major receptors targeted by epinephrine and norepinephrine

Interleukin-1 (IL-1) structural pathway

ErbB signaling pathway

Non-small cell lung cancer

Methionine de novo and salvage pathway

Non-canonical Wnt pathway

Affected pathways in Duchenne muscular dystrophy

Purine metabolism

Cardiac progenitor differentiation

Glycolysis in senescence

Non-homologous end joining

Kallmann syndrome

Pentose phosphate pathway in senescent cells

Primary ovarian insufficiency

TCA cycle

17p13.3 (YWHAE) copy number variation

5q35 copy number variation

Pleural mesothelioma

Wnt signaling

Translation inhibitors in chronically activated PDGFRA cells

Hedgehog signaling pathway

Fibrin complement receptor 3 signaling pathway

Clear cell renal cell carcinoma pathways

Cell cycle

Transcriptional activation by NRF2 in response to phytochemicals

PDGFR-beta pathway

Focal adhesion

Complement system

Prader-Willi and Angelman syndrome

8p23.1 copy number variation syndrome

1p36 copy number variation syndrome

Gibberellin A12 biosynthesis

Alanine and aspartate metabolism

DYRK1A involvement regarding cell proliferation in brain development

CBD synthetic pathway

D-arginine and D-ornithine metabolism

Osteoblast signaling

Genetic alterations of lung cancer

Pantothenate and coenzyme A biosynthesis

Nicotine effect on chromaffin cells

Osteoclast signaling

ALA oxylipin metabolism

Ergosterol biosynthesis

Electron transport chain: OXPHOS system in mitochondria

Comprehensive IL-17A signaling

Aryl hydrocarbon receptor pathway

IL-26 signaling pathways

Octadecanoid formation from linoleic acid

CCL18 signaling pathway

Integrated cancer pathway

Cori cycle

Mechanisms associated with pluripotency

TP53 network

Folate-alcohol and cancer pathway hypotheses

Metapathway signal transduction

MicroRNAs in cardiomyocyte hypertrophy

Energy metabolism

miRNA regulation of DNA damage response

Glycine metabolism

Oncostatin M signaling pathway

Corticotropin-releasing hormone signaling pathway

AGE/RAGE pathway

Thymic stromal lymphopoietin (TSLP) signaling pathway

Nicotine effect on dopaminergic neurons

Fluoropyrimidine activity

Mitochondrial long chain fatty acid beta-oxidation

Parkinson's disease

IL-7 signaling pathway

Target of rapamycin signaling

Serotonin transporter activity

IL-4 signaling pathway

VEGFA-VEGFR2 signaling

Apoptosis modulation by HSP70

MAPK signaling pathway

Triacylglyceride synthesis

Osteoblast signaling

Notch signaling

Small ligand GPCRs

Prolactin signaling pathway

TNF-related weak inducer of apoptosis (TWEAK) signaling pathway

Follicle stimulating hormone (FSH) signaling pathway

Thyroid stimulating hormone (TSH) signaling pathway

RANKL/RANK signaling pathway

Response regulator aspartate phosphatase interactions

Valine, leucine and isoleucine degradation

Androgen receptor signaling pathway

IL-2 signaling pathway

EGF/EGFR signaling pathway

mRNA processing

Eukaryotic transcription initiation

p38 MAPK signaling pathway

Wnt signaling pathway

Fas ligand pathway and stress induction of heat shock proteins

Nuclear receptors in lipid metabolism and toxicity

Myometrial relaxation and contraction pathways

S1P receptor signal transduction

TOR signaling

Osteopontin signaling

B cell receptor signaling pathway

IL-9 signaling pathway

Homologous recombination

Integrin-mediated cell adhesion

Bone morphogenic protein signaling and regulation

Pentose phosphate metabolism

IL-5 signaling pathway

TGF-beta receptor signaling

Complement and coagulation cascades

Biogenic amine synthesis

Calcium regulation in cardiac cells

Hypertrophy model

Glucuronidation

Sulfation biotransformation reaction

T-cell receptor signaling pathway

Arachidonate epoxygenase / epoxide hydrolase

Glucose homeostasis

Flower development

Glycogen synthesis and degradation

Prostaglandin synthesis and regulation

DNA damage response (only ATM dependent)

Elongation of (very) long chain fatty acids

Male steroid hormones in cardiomyocyte energy metabolism

Bacterial ceramide synthesis

Serotonin receptor 4/6/7 and NR3C signaling

Serotonin receptor 2 and ELK-SRF/GATA4 signaling

Serotonin HTR1 group and FOS pathway

Serotonin transporter activity

Female steroid hormones in cardiomyocyte energy metabolism

Serotonin receptor 4/6/7 and NR3C signaling

Serotonin receptor 2 and ELK-SRF / GATA4 signaling

Serotonin receptor 2 and STAT3 signaling

Serotonin receptor 2 and STAT3 signaling

ACE2 inhibition leads to pulmonary fibrosis

IL-9 signaling pathway

Amino acid conjugation of benzoic acid

IL-6 signaling pathway

Lactate shuttle in glial cells

Metabolic pathways of fibroblasts

Sebaleic acid formation and metabolism

Cysteine biosynthesis from homoserine

Meiotic recombination genes

Osteoclast signaling

GPCRs, class A rhodopsin-like

Nuclear factor, erythroid-derived 2, like 2 signaling pathway

Pyruvate dehydrogenase pathway

Sucrose biosynthesis

Metapathway biotransformation

Colanic acid building blocks biosynthesis

Neurogenesis regulation in the olfactory epithelium

Type I interferon induction and signaling during SARS-CoV-2 infection

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Mevalonate pathway

Glycerol teichoic acid biosynthesis

Lacto series sphingolipid metabolism

Ganglio series sphingolipid metabolism

Catecholamine synthesis

Oxidative stress and redox pathway

Metabolism of tetrahydrocannabinol (THC)

Primary focal segmental glomerulosclerosis (FSGS)

Primary carbon metabolism

Carbon assimilation C4 pathway

Oxidation by cytochrome P450

Oxidation by cytochrome P450

mRNA processing

Aflatoxin B1 metabolism

Ureide biosynthesis

Heme biosynthesis

TCA cycle in senescence

Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling

Nod-like receptor (NLR) signaling pathway

Pregnane X receptor pathway

Eicosanoid synthesis

Selenium micronutrient network

Fatty acid beta-oxidation

Folic acid network

Retinol metabolism

Folic acid network

Retinol metabolism

Sulfur amino acid biosynthesis

Triacylglyceride synthesis

Hippocampal synaptogenesis and neurogenesis

Docosahexaenoic acid oxylipin metabolism

mRNA processing

Myometrial relaxation and contraction pathways

Myometrial relaxation and contraction pathways

Semaphorin interactions

mRNA processing

mRNA processing

Myometrial relaxation and contraction pathways

Notch signaling pathway

mRNA processing

mRNA Processing

TLR4 signaling and tolerance

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

PDGF pathway

Folate metabolism

Vitamin B12 metabolism

Retinoblastoma gene in cancer

Glycolysis and gluconeogenesis

Pluripotent stem cell differentiation pathway

Allograft rejection

MAPK pathway in congenital thyroid cancer

Microglia pathogen phagocytosis pathway

Regulation of actin cytoskeleton

Biogenic amine synthesis

Quercetin and Nf-kB / AP-1 induced apoptosis

ID signaling pathway

ID signaling pathway

ID signaling pathway

TGF-beta signaling pathway

TNF-alpha signaling pathway

ID signaling pathway

Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex

Melatonin metabolism and effects

Aryl hydrocarbon receptor pathway

Hijack of ubiquitination by SARS-CoV-2

SARS-CoV-2 and COVID-19 pathway

BDNF pathway

Insulin signaling

RAC1/PAK1/p38/MMP2 pathway

Photodynamic therapy-induced AP-1 survival signaling

Long-day flowering time pathway

Cell differentiation - index

Spinal cord injury

Statin inhibition of cholesterol production

Parkin-ubiquitin proteasomal system pathway

Vitamin D receptor pathway

Nod-like receptor (NLR) signaling pathway

Nicotine metabolism in liver cells

Tryptophan metabolism

Metabolism of alpha-linolenic acid

Blood clotting and drug effects

Role of carnosine in muscle contraction

Host-pathogen interaction of human coronaviruses - MAPK signaling

Wnt signaling pathway and pluripotency

Primary focal segmental glomerulosclerosis (FSGS)

Arrhythmogenic right ventricular cardiomyopathy

HIF1A and PPARG regulation of glycolysis

EGF/EGFR signaling pathway

NAD+ metabolism

Endoplasmic reticulum stress response in coronavirus infection

NAD+ biosynthetic pathways

miR-222 in exercise-induced cardiac growth

Flowering time pathway

Metabolic reprogramming in colon cancer

Nodal signaling pathway

Dauer formation

Glycogen metabolism

Flavonoid pathway

ER stress-unfolded protein response (UPRer)

Heterchronic control of molting

Pathogenic Escherichia coli infection

FGF signaling pathway

Cell division: first embryonic mitosis

Folate biosynthesis

Ascaroside biosynthesis

Wnt signaling pathway and pluripotency

EGFR1 signaling pathway

Eukaryotic transcription initiation

Exercise-induced circadian regulation

Canonical NF-kB pathway

Osteoclast signaling

Kit receptor signaling pathway

IL-6 signaling pathway

Aryl hydrocarbon receptor pathway

Glycogen metabolism

Electron transport chain

Delta-Notch signaling pathway

Wnt signaling

IL-17 signaling pathway

Neural crest differentiation

GPCRs, orphan

Endochondral ossification

Delta-Notch signaling pathway

Hedgehog signaling pathway

Methylation pathways

Catalytic cycle of mammalian flavin-containing monooxygenases (FMOs)

DNA mismatch repair

GPCRs, class C metabotropic glutamate, pheromone

Neural crest cell migration in cancer

Neural crest cell migration during development

GPCRs, class A rhodopsin-like

Acrylamide biotransformation and exposure biomarkers

Tgif disruption of Shh signaling

lncRNA-mediated mechanisms of therapeutic resistance

Interactions between LOXL4 and oxidative stress pathway

GPCRs, class B secretin-like

Estrogen receptor pathway

Glucocorticoid receptor pathway

Constitutive androstane receptor pathway

Hair follicle development: organogenesis - part 2 of 3

Cardiac hypertrophic response

Diclofenac metabolic pathway

Gastric cancer network 2

Gastric cancer network 1

Endothelin pathways

Fatty acid omega-oxidation

SRF and miRs in smooth muscle differentiation and proliferation

GPCRs, other

Cytokines and inflammatory response

Methylation pathways

Nuclear receptors in lipid metabolism and toxicity

Glycogen metabolism

Nuclear receptors

Delta-Notch signaling pathway

Hedgehog signaling pathway

Kit receptor signaling pathway

EGFR1 signaling pathway

Fatty acid omega-oxidation

Globo sphingolipid metabolism

Aryl hydrocarbon receptor

ATM signaling pathway

Interleukin-11 signaling pathway

AMPK signaling

Folate-alcohol and cancer pathway

Isoprenoid precursor biosynthesis in Pf apicoplasts

NAD biosynthesis I from aspartate

Osteoblast signaling

Beta-alanine biosynthesis

Carotenoid biosynthesis

Ganglio sphingolipid metabolism

Glycogen metabolism

Nuclear receptors

Statin pathway

Hedgehog signaling pathway

Kit receptor signaling pathway

Electron transport chain

Cytokines and inflammatory response

EGFR1 signaling pathway

Glycogen metabolism

Nuclear receptors

Endochondral ossification

Notch signaling pathway

Complement and coagulation cascades

TGF-beta signaling pathway

Statin pathway

B cell receptor signaling pathway

Hedgehog signaling pathway

Electron transport chain

Glycolysis and gluconeogenesis

MAPK signaling pathway

Methionine degradation

Threonine biosynthesis

Tryptophan degradation

Starch and cellulose biosynthesis

Homocysteine and cysteine interconversion

Principal pathways of carbon metabolism

Nuclear receptors

Inhibitor of DNA binding (ID) signaling pathway

Hedgehog signaling pathway

Kit receptor signaling pathway

Triacylglycerol biosynthesis

Biosynthesis of gamma-aminobutyric acid (GABA) by polyamine oxidation

Chlorophyll b degradation

Flower development: initiation

Glycogen metabolism

Delta-Notch signaling pathway

Calcium regulation in cardiac cells

EGFR1 signaling pathway

Polyol pathway

GPR40 pathway

Imatinib and chronic myeloid leukemia

T cell receptor and co-stimulatory signaling

NAD biosynthesis II (from tryptophan)

miRNA biogenesis

Microtubule cytoskeleton regulation

G13 signaling pathway

Exercise-induced circadian regulation

Nod-like receptor (NLR) signaling pathway

Hedgehog signaling pathway

Complement and coagulation cascades

Mitochondrial unfolded-protein response

Hedgehog signaling pathway

Osteoclast

Cytoplasmic ribosomal proteins

Lipid droplet metabolism

Thick ascending limb transporters

Proximal tubule transporters

Glial cell differentiation

mir219 in oligodendrocyte differentiation and myelination

Nuclear receptors

Glycogen metabolism

Kit receptor signaling pathway

Statin pathway

Nod-like receptor (NLR) signaling pathway

Nod-like receptor (NLR) signaling pathway

Homologous recombination

Nod-like receptor (NLR) signaling pathway

Glycogen metabolism

Glycolysis and gluconeogenesis

Estrogen signaling

Monoamine transport

Exercise-induced circadian regulation

Synthesis and degradation of ketone bodies

Biogenic amine synthesis

Microglia pathogen phagocytosis pathway

Common pathways underlying drug addiction

Glycolysis and gluconeogenesis

MicroRNAs in cardiomyocyte hypertrophy

Biogenic amine synthesis

Electron transport chain

p38 MAPK signaling pathway

Integrin-mediated cell adhesion

MAPK cascade

p38 Mapk signaling pathway

ESC pluripotency pathways

Biotic stress response gene network

TYROBP causal network in microglia

Tyrobp causal network in microglia

Ebstein-Barr virus LMP1 signaling

Irinotecan pathway

Glutathione and one-carbon metabolism

Host-pathogen interaction of human coronaviruses - apoptosis

Host-pathogen interaction of human coronaviruses - autophagy

One-carbon metabolism

Retinoblastoma gene in cancer

Toll-like receptor signaling

PI3K/AKT/mTOR - vitamin D3 signaling

Nanomaterial-induced inflammasome activation

Farnesoid X receptor pathway

PPAR-alpha pathway

Liver X receptor pathway

Endoderm differentiation

Nuclear receptors

Androgen receptor signaling pathway

Kit receptor signaling pathway

Androgen receptor signaling pathway

ID signaling pathway

Androgen receptor signaling pathway

Wnt Signaling Pathway and Pluripotency

Histidine metabolism

Ptf1a related regulatory pathway

Regulation of Pgc1a expression by a Gsk3b-Tfeb signaling axis in skeletal muscle

Influenza A virus infection

Hexoses metabolism in proximal tubules

Corticotropin-releasing hormone

mir-193a and MVP in colon cancer metastasis

Transcriptional cascade regulating adipogenesis

Macrophage markers

Estrogen metabolism

Oxidative phosphorylation

Angiotensin II signaling (acute) in thick ascending limbs

Gonadotropin-releasing hormone (GnRH) signaling

Cocaine metabolism

Gluconeogenesis

Cadmium and glutathione

Fatty acid oxidation

PPAR signaling pathway

Lycopene biosynthesis

NRF2 pathway

Novel intracellular components of RIG-I-like receptor pathway

H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Extracellular vesicle-mediated signaling in recipient cells

Benzo(a)pyrene metabolism

Arylamine metabolism

Estrogen signaling pathway

Vitamins A and D - action mechanisms

Acetaminophen synthesis

NAD salvage pathway III

NAD salvage pathway II

NAD salvage pathway I

Adipogenesis

Biosynthesis and regulation of nematode bile acids

Estrogen metabolism

Nonalcoholic fatty liver disease

Chemokine signaling pathway

Glutamate degradation I

Heterochronic gene regulation of development

Hfe effect on hepcidin production

Apoptosis

Lipoic acid metabolism

Ascorbate and aldarate metabolism

Brain derived neurotrophic factor

Hfe effect on hepcidin production

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

Nuclear Receptors

eIF5A regulation in response to inhibition of the nuclear export system

Gene regulatory network modelling somitogenesis

Gastric cancer network 2

Glycolysis

Gene regulatory network modelling somitogenesis

Neurotransmitter release in cholinergic motor neurons

EBV LMP1 signaling

Metapathway biotransformation

Histone modifications

Type II interferon signaling (IFNG)