ID signaling pathway (WP934)

Pan troglodytes

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Inhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA binding capacity. This family of proteins is comprised of IDs 1, 2, 3 and 4. They can be stimulated by ligands such as the Vascular Endothelial Growth Factor (VEGF), TGF beta and the T cell receptor. Source: NetPath http://www.netpath.org/pathways?path_id=NetPath_5

Authors

Alex Pico , Christine Chichester , and Eric Weitz

Activity

last edited

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Organisms

Pan troglodytes

Communities

Annotations

Pathway Ontology

Inhibitor of DNA binding signaling pathway

Participants

Label Type Compact URI Comment
ID1 GeneProduct ncbigene:469912
ID3 GeneProduct ncbigene:745532
ID4 GeneProduct ncbigene:747716
RB1 GeneProduct ncbigene:452715
RBL2 GeneProduct ncbigene:467978
RBL1 GeneProduct ncbigene:735916
MYOD1 GeneProduct ncbigene:451057
CDK2 GeneProduct ncbigene:467032
CCNA2 GeneProduct ncbigene:461467
CCNE1 GeneProduct ncbigene:455914
ELK4 GeneProduct ncbigene:742304
ELK3 GeneProduct ncbigene:467100
PSMD4 GeneProduct ncbigene:100192399
HES1 GeneProduct ncbigene:460942
PAX5 GeneProduct ncbigene:747452
PAX2 GeneProduct ncbigene:744540
PAX8 GeneProduct ncbigene:459503
MYF5 GeneProduct ncbigene:467081
MYF6 GeneProduct ncbigene:745321
TCF12 GeneProduct ncbigene:453466
SREBF1 GeneProduct ncbigene:454480
MSC GeneProduct ncbigene:472790
IFI16 GeneProduct ncbigene:457424
BMP2 GeneProduct ncbigene:458090
BMPR2 GeneProduct ncbigene:459885
FLT1 GeneProduct ncbigene:452512
KDR GeneProduct ncbigene:461315
SMAD1 GeneProduct ncbigene:450142
SMAD4 GeneProduct ncbigene:468537
SMAD5 GeneProduct ncbigene:745633
ATF3 GeneProduct ncbigene:469143
SMAD3 GeneProduct ncbigene:748161
TGIF1 GeneProduct ncbigene:455312
ACVRL1 GeneProduct ncbigene:451910
IGF1R GeneProduct ncbigene:453676
IGF1 GeneProduct ncbigene:741055
IRS1 GeneProduct ncbigene:459985
CTNNB1 GeneProduct ncbigene:450183
TERT GeneProduct ncbigene:471443
NFKB1 GeneProduct ncbigene:461406
RELA GeneProduct ncbigene:466665
BMP6 GeneProduct ncbigene:471851
CD40LG GeneProduct ncbigene:473802
NGF GeneProduct ncbigene:469423
EGF GeneProduct ncbigene:461435
TCF7L2 GeneProduct ncbigene:455432

References