DeSl

Disorders of mitochondrial homeostatis, dynamics, protein import, and quality control

Joubert syndrome

Heroin metabolism

SCFA and skeletal muscle substrate metabolism

Disorders of galactose metabolism

Electron transport chain: OXPHOS system in mitochondria

Pathways of nucleic acid metabolism and innate immune sensing

Pyrimidine metabolism

Fatty acid beta-oxidation

Serotonin HTR1 group and FOS pathway

Mitochondrial fatty acid oxidation disorders

NAD salvage pathway V

Glucose-1-phosphate metabolism

Gluconeogenesis

Chorismate biosynthesis

Cysteine biosynthesis from homoserine

Colanic acid building blocks biosynthesis

Pentose phosphate pathway

Complement and coagulation cascades

Pentose pathway, non-oxidative branch

Mammary gland development: involution - stage 4 of 4

Mammary gland development: puberty - stage 2 of 4

Mammary gland development: embryonic development - stage 1 of 4

Hepatocyte growth factor receptor signaling

Integrated breast cancer pathway

Somatroph axis (GH) and its relationship to dietary restriction and aging

Omega-3-fatty acids in senescence

Mammary gland development: pregnancy and lactation - stage 3 of 4

Type I interferon induction and signaling during SARS-CoV-2 infection

Fatty acid and lipoprotein transport in hepatocytes

Homocysteine and cysteine interconversion

MAPK signaling pathway

Steroidogenic pathway

Threonine biosynthesis

Glycolysis

Metabolic pathway of LDL, HDL and TG, including diseases

Histidine, purine, and pyrimidine superpathway

Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids

Vitamin K metabolism and activation of dependent proteins

Statin inhibition of cholesterol production

Gastrin signaling

Left-right asymmetry in the nervous system

Heterochronic gene regulation of development

Pentose phosphate metabolism

Principal pathways of carbon metabolism

Follicle stimulating hormone (FSH) signaling

Cholesterol biosynthesis pathway in hepatocytes

Trans-sulfuration, one-carbon metabolism and related pathways

Irinotecan pathway

Osteoarthritic chondrocyte hypertrophy

Ras signaling

Hepatocyte growth factor receptor signaling

Spinal cord injury

Vitamin D in inflammatory diseases

Neovascularization processes

PI3K/AKT/mTOR - vitamin D3 signaling

Pathogenic Escherichia coli infection

Vitamin B12 metabolism

Tamoxifen metabolism

UDP-glucose conversion

Toll-like receptor signaling

Focal adhesion: PI3K-Akt-mTOR-signaling

CAMKK2 pathway

Non-genomic actions of 1,25-dihydroxyvitamin D3

Serotonin receptor 2 and ELK-SRF/GATA4 signaling

LDL- influence on CD14 and TLR4

Calcium regulation in cardiac cells

G1 to S cell cycle control

Mitochondrial complex I assembly model OXPHOS system

Mitochondrial fatty acid synthesis pathway

Ferroptosis

TP53 network

Estrogen metabolism

Synthesis of ceramides and 1-deoxyceramides

Biosynthesis and turnover of 1-deoxy-sphingoid bases

Fluoroacetic acid toxicity

Major receptors targeted by epinephrine and norepinephrine

Metabolism of alpha-linolenic acid

Blood clotting and drug effects

Translation inhibitors in chronically activated PDGFRA cells

Interactions between immune cells and microRNAs in tumor microenvironment

Genes related to primary cilium development (based on CRISPR)

Cysteine and methionine catabolism

Ophthalmate biosynthesis in hepatocytes

Control of immune tolerance by vasoactive intestinal peptide

Platelet-mediated interactions with vascular and circulating cells

Inflammatory response pathway

DYRK1A involvement regarding cell proliferation in brain development

1q21.1 copy number variation syndrome

Purine metabolism

Prader-Willi and Angelman syndrome

ADHD and autism (ASD) pathways

Lactate shuttle in glial cells

Glucocorticoid biosynthesis

Mineralocorticoid biosynthesis

Farnesyl to CoQ10 metabolism

Roles of ceramides in development of insulin resistance

Phosphoinositides metabolism

Complement system

Amino acid conjugation

Aflatoxin B1 metabolism

Glucuronidation

Estrogen metabolism

Arylamine metabolism

Arachidonate epoxygenase / epoxide hydrolase

Oxidative phosphorylation

Omega-6-fatty acids in senescence

Sulfatase and aromatase pathway

Autophagy in pancreatic ductal adenocarcinoma

Isoglobo series sphingolipids

Sildenafil treatment

TCA cycle

Aerobic glycolysis

ESC pluripotency pathways

Aerobic glycolysis - augmented

Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism

Biotic stress response gene network

Rett syndrome

Flavan-3-ol metabolic pathway

Purine metabolism and related disorders

Ebola virus infection in host

Embryonic stem cell pluripotency pathways

Pluripotent stem cell differentiation pathway

Hair follicle development: cytodifferentiation - stage 3 of 3

Quercetin and Nf-kB / AP-1 induced apoptosis

RANKL/RANK signaling

Monoamine transport

Vitamin A and carotenoid metabolism

MAPK cascade

Sulfur amino acid biosynthesis

Folate metabolism

Sucrose biosynthesis

Histidine metabolism

Folic acid biosynthesis

Common pathways underlying drug addiction

Pilocytic astrocytoma

Notch signaling

TGFB / Smad signaling

Netrin-UNC5B signaling

Hedgehog signaling

Interferon-mediated signaling

Regulatory circuits of STAT3 signaling

IL10 anti-inflammatory signaling

PPAR signaling

MAPK signaling

Wnt signaling

Thyroid stimulating hormone (TSH) signaling

Resolvin E1 and resolvin D1 signaling decrease inflammation

PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer

Involvement of δ-secretase in neurodegenerative diseases

Enterocyte cholesterol metabolism

Bile acid synthesis and enterohepatic circulation

Sulfur degradation

Head and neck squamous cell carcinoma

Oligodendrocyte specification and differentiation, leading to myelin components for CNS

Lipids measured in liver metastasis from breast cancer

Modified nucleosides derived from tRNA as urinary cancer markers

Degradation pathway of sphingolipids, including diseases

Thiamine metabolic pathways

Poly(glycerol phosphate) wall teichoic acid biosynthesis

Glial cell differentiation

RAS and bradykinin pathways in COVID-19

TCA cycle (aka Krebs or citric acid cycle)

Steroid biosynthesis

Glutathione metabolism

Endochondral ossification

Effect of progerin on genes involved in progeria

Lamin A processing pathway

Hypoxia-dependent differentiation of myoblasts

Cell-type dependent selectivity of CCK2R signaling

Focal adhesion: PI3K-Akt-mTOR signaling pathway

DNA replication

One-carbon metabolism

GABA receptor signaling

TCA cycle nutrient use and invasiveness of ovarian cancer

Irinotecan pathway

Irinotecan pathway

Evolocumab mechanism to reduce LDL cholesterol

Vitamin D metabolism

ACE inhibitor pathway

7-oxo-C and 7-beta-HC pathways

Amino acid transport defects (IEMs)

Alternative pathway of fetal androgen synthesis

Enterohepatic circulation of bile acids

Steroid hormone precursor biosynthesis

Cholesterol biosynthesis with skeletal dysplasias

Oxysterols derived from cholesterol

Disorders of folate metabolism and transport

Riboflavin and CoQ disorders

Linoleic acid metabolism affected by SARS-CoV-2

Vitamin B6-dependent and responsive disorders

Neurotransmitter disorders

Metabolism of sphingolipids in ER and Golgi apparatus

Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway

Type II diabetes mellitus

Sphingolipid metabolism overview

Chronic hyperglycemia impairment of neuron function

Ether lipid biosynthesis

Disorders in ketolysis

Creatine pathway

Copper metabolism

Disorders of bile acid synthesis and biliary transport

Disorders in ketone body synthesis

Iron metabolism disorders

Hemesynthesis defects and porphyrias

Glyoxylate metabolism

Ethylmalonic encephalopathy

FGFR3 signaling in chondrocyte proliferation and terminal differentiation

Leucine, isoleucine and valine metabolism

Urea cycle and associated pathways

Urea cycle and related diseases

Glycosylation and related congenital defects

Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases

Molybdenum cofactor (Moco) biosynthesis

Methionine metabolism leading to sulfur amino acids and related disorders

MTHFR deficiency

Vitamin B12 disorders

Krebs cycle disorders

Pyrimidine metabolism and related diseases

GABA metabolism (aka GHB)

Cholesterol synthesis disorders

Proline and hydroxyproline pathways

Cerebral organic acidurias, including diseases

Tyrosine metabolism and related disorders

Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine

Codeine and morphine metabolism

Amyotrophic lateral sclerosis (ALS)

Cholesterol biosynthesis pathway

Fructose and mannose metabolism

Glycolysis and gluconeogenesis

Monoamine GPCRs

Glycine metabolism, including IMDs

Metapathway biotransformation Phase I and II

Methionine de novo and salvage pathway

Non-canonical Wnt pathway

Purine metabolism

Non-homologous end joining

Primary ovarian insufficiency

Kennedy pathway from sphingolipids

Wnt signaling

Cell cycle

EGFR tyrosine kinase inhibitor resistance

Gibberellin A12 biosynthesis

Diet-dependent trimethylamine/trimethylamine N-oxide metabolism

Osteoblast signaling

Nuclear receptors meta-pathway

Glycerophospholipid biosynthetic pathway

Aryl hydrocarbon receptor pathway

Eicosanoid metabolism via cyclooxygenases (COX)

Cori cycle

Peroxisomal beta-oxidation of tetracosanoyl-CoA

Kennedy pathway

Energy metabolism

Flavonoid biosynthesis

Nicotine effect on dopaminergic neurons

Fluoropyrimidine activity

VEGFA-VEGFR2 signaling

S1P receptor signal transduction

Sulfation biotransformation reaction

Glycogen synthesis and degradation

Prostaglandin synthesis and regulation

Omega-9 fatty acid synthesis

Eicosanoid metabolism via lipoxygenases (LOX)

Fructose metabolism in proximal tubules

Elongation of (very) long chain fatty acids

Bacterial ceramide synthesis

Serotonin receptor 4/6/7 and NR3C signaling

Serotonin transporter activity

GPCRs, class A rhodopsin-like

Retinol metabolism

Fatty acid biosynthesis

Fatty acid biosynthesis

Fatty acid biosynthesis

Glycerophospholipid biosynthetic pathway

Glycerol teichoic acid biosynthesis

PtdIns(4,5)P2 in cytokinesis pathway

Leukotriene metabolic pathway

Oxidative stress and redox pathway

Metabolism of tetrahydrocannabinol (THC)

SK UDPglcnac

Pentose phosphate pathway

Primary focal segmental glomerulosclerosis (FSGS)

DNA replication

Translation factors

mRNA processing

Cholesterol metabolism with Bloch and Kandutsch-Russell pathways

Heme biosynthesis

Deregulation of renin-angiotensin system by SARS-CoV infection

Sphingolipid metabolism: integrated pathway

Omega-9 fatty acid synthesis

Omega-3 / omega-6 fatty acid synthesis

Glycerolipids and glycerophospholipids

Eicosanoid metabolism via lipooxygenases (LOX)

Eicosanoid metabolism via cytochrome P450 monooxygenases pathway

Cholesterol metabolism with Bloch and Kandutsch-Russell pathways

Sphingolipid metabolism (integrated pathway)

Omega-3 / omega-6 fatty acid synthesis

Eicosanoid metabolism via cytochrome P450 monooxygenases

Eicosanoid metabolism via cyclooxygenases (COX)

Glycerolipids and glycerophospholipids

Sphingolipid metabolism overview

Brassinolide biosynthetic pathway

Heme biosynthesis

Eicosanoid synthesis

Selenium micronutrient network

Effect of intestinal microbiome on anticoagulant response of vitamin K antagonists

COVID-19 and endothelial cell senescence

Mitochondrial beta-oxidation

Phospholipid biosynthesis

Pro-survival signaling of neuroprotectin D1

COVID-19, thrombosis and anticoagulation

Glycolysis and gluconeogenesis

Acetogenesis

Allograft rejection

Microglia pathogen phagocytosis pathway

DNA IR-damage and cellular response via ATR

TGF-beta signaling pathway

Aryl hydrocarbon receptor pathway

Serine metabolism

Cell differentiation - index

Beta-oxidation of unsaturated fatty acids

Mevalonate arm of cholesterol biosynthesis pathway with inhibitors

Trehalose degradation, low osmolarity

Effect of L-carnitine on metabolism

Nicotine metabolism in liver cells

Tryptophan metabolism

Biomarkers for pyrimidine metabolism disorders

Role of carnosine in muscle contraction

Hormonal control of pubertal growth spurt

Host-pathogen interaction of human coronaviruses - MAPK signaling

Ketogenesis and ketolysis

Biotin metabolism, including IMDs

Urea cycle and metabolism of amino groups

Hepatocyte growth factor receptor signaling

Hepatocyte growth factor receptor signaling

Hepatocyte growth factor receptor signaling

Fatty acid beta-oxidation 3

Mitochondrial long chain fatty acid beta-oxidation

Triacylglyceride synthesis

BMP signaling pathway

Fatty acid beta-oxidation 2

Mevalonate arm of cholesterol biosynthesis pathway

ERK1-ERK2 MAPK cascade

Cannabinoid receptor signaling

Caffeine and theobromine metabolism

Flavonoid pathway

Sucrose metabolism

FGF signaling pathway

Sphingolipid pathway

Fatty acid beta-oxidation 1

Regulation of Wnt / B-catenin signaling by small molecule compounds

Wnt signaling pathway and pluripotency

Pentose phosphate pathway

Mapk signaling pathway

Eicosanoid lipid synthesis map

BMP signaling pathway in eyelid development

Catalytic cycle of mammalian flavin-containing monooxygenases (FMOs)

DNA repair pathways, full network

Amino acid metabolism pathway excerpt: histidine catabolism extension

Toll-like receptor signaling related to MyD88

Tgif disruption of Shh signaling

Biochemical pathways: part I

Lipid particles composition

Circadian rhythm genes

Hair follicle development: organogenesis - part 2 of 3

Sulindac metabolic pathway

Diclofenac metabolic pathway

TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc)

Fatty acid omega-oxidation

Prostaglandin synthesis and regulation

Heme biosynthesis

Monoterpene biosynthesis pathway in mint

Apoptosis modulation and signaling

Polar auxin transport

Isoprenoid precursor biosynthesis in Pf apicoplasts

Carotenoid biosynthesis

Ganglio sphingolipid metabolism

Glycogen metabolism

Glycolysis and gluconeogenesis

Glycogen catabolism

Methionine degradation

Trehalose anabolism

Riboflavin, FMN, and FAD biosynthesis

Phenylalanine, tyrosine, and tryptophan biosynthesis

Starch and cellulose biosynthesis

Phenylalanine biosynthesis

Tryptophan biosynthesis

Biosynthesis of gamma-aminobutyric acid (GABA) by polyamine oxidation

Chlorophyll b degradation

Polyol pathway

Steroid biosynthesis

Thick ascending limb transporters

Chicken limb development

Sulindac metabolic pathway

Glycogen metabolism

Microglia pathogen phagocytosis pathway

Biogenic amine synthesis

Cholesterol biosynthesis

Integrin-mediated cell adhesion

p38 Mapk signaling pathway

Renin-angiotensin system

Metabolism overview

One-carbon metabolism and related pathways

Lactose degradation and galactose metabolism

Monoamine GPCRs

Sulfate assimilation and copper detoxification

RuMP cycle, oxidative branch of the pentose phosphate pathway and formaldehyde assimilation

Amino acid conjugation of benzoic acid

Acetate mediated promotion of metabolic syndrome

Nanomaterial induced apoptosis

Regulation of Pgc1a expression by a Gsk3b-Tfeb signaling axis in skeletal muscle

Hexoses metabolism in proximal tubules

Vanillin and isovanillin metabolism

Biomarkers for urea cycle disorders

Angiotensin II signaling (acute) in thick ascending limbs

Valproic acid pathway

Glutathione metabolism

Dopamine metabolism

Cocaine metabolism

Dopamine metabolism

PPAR signaling pathway

Oryzalexin S biosynthesis

Lycopene biosynthesis

Caloric restriction and aging

mRNA, protein, and metabolite inducation pathway by cyclosporin A

Lidocaine metabolism

Butyrate-induced histone acetylation

Iron uptake and transport

Phosphatidylcholine catabolism

Serotonin and anxiety

Methylerythritol phosphate pathway

CRD motif and sFRPs influence on Wnt signaling

Tryptophan catabolism leading to NAD+ production

Lipoic acid metabolism

Ascorbate and aldarate metabolism

Ethylene signaling pathway