Monoterpene biosynthesis pathway in mint (WP4701)

Vitis vinifera

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Monoterpenes (C10) are the major group of compounds within the essential oils of the mint (Lamiaceae) family. Peppermint (Mentha × piperita)is considered a model system for the study of monoterpene metabolism, which main steps are depicted in this pathway. This pathway is annotated well enough for data analysis, however please do not add the "Approved Version" tag yet, since this allocates the PW to the incorrect species (grape vs mint). The WikiPathways team is working on a solution.

Authors

Aishwarya Vellanki , Marvin Martens , Denise Slenter , Friederike Ehrhart , and Eric Weitz

Activity

last edited

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Organisms

Vitis vinifera

Communities

Annotations

Pathway Ontology

monoterpene biosynthetic pathway

Participants

Label Type Compact URI Comment
(+)-Pulegone Metabolite kegg.compound:C09893
(-)-Menthone Metabolite kegg.compound:C00843
(+)-cis-Isopulegone Metabolite kegg.compound:C11951
(+)-Isomenthone Metabolite kegg.compound:C11952
(-)-trans-Carveol Metabolite kegg.compound:C00964
(-)-trans-Isopiperitenol Metabolite kegg.compound:C01123
(+)-Neomenthol Metabolite kegg.compound:C00553
(-)-Limonene Metabolite kegg.compound:C00521
(-)-Carvone Metabolite kegg.compound:C01767
(-)-Menthol Metabolite kegg.compound:C00400
(+)-Menthofuran Metabolite kegg.compound:C18025
Geranyl diphosphate Metabolite kegg.compound:C00341
PR Protein ncbiprotein:AAQ75423.1 (+)-pulegone reductase https://www.ncbi.nlm.nih.gov/protein/34559418 ---------PulR-1------------ M. longifolia Chromosome: 3 Location Identifier: Mlong585_09229 Number of Introns: 4 Expression Level in Glandular Trichomes[TPM]: 3116 Homology to Canonical Genes: 95 % identity to Q6WAU0 ---------PulR-2------------ M. longifolia Chromosome: 3 Location Identifier: Mlong585_09276 Number of Introns: 4 Expression Level in Glandular Trichomes[TPM]: 3116 Homology to Canonical Genes: 95 % identity to Q6WAU0 Mlong585_09276 ---------PulR-3------------ M. longifolia Chromosome: 3 Location Identifier: Mlong585_09230 Number of Introns: 0 Expression Level in Glandular Trichomes[TPM]: n/a Homology to Canonical Genes: pseudogene (premature stop codon) ---------PulR-L1------------ M. longifolia Chromosome: 2 Location Identifier: Mlong585_06346 Number of Introns: 4 Expression Level in Glandular Trichomes[TPM]: 153 Homology to Canonical Genes: 92 % identity to Q6WAU0
CDH Protein ncbiprotein:ABR15424.1 (-)-trans-carveol dehydrogenase https://www.ncbi.nlm.nih.gov/protein/148887811
ISPR Protein ncbiprotein:AAQ75422.1 (-)-trans-isopipertenone reductase (-)-Isopiperitenone reductase https://www.ncbi.nlm.nih.gov/protein/34559416 ---------ISPR-1------------ M. longifolia Chromosome: 11 Location Identifier: Mlong585_36604 Number of Introns: 4 Expression Level in Glandular Trichomes[TPM]: 20 Homology to Canonical Genes: 94 % identity to Q6WAU1 ---------ISPR-2------------ M. longifolia Chromosome: 11 Location Identifier: Mlong585_36605 Number of Introns: 4 Expression Level in Glandular Trichomes[TPM]: 20 Homology to Canonical Genes: 99 % identity to Q6WAU1
MFS Protein ncbiprotein:ABW86890.1 (+)-menthofuran synthase https://www.ncbi.nlm.nih.gov/protein/158979036 ---------MFS-L1------------ M. longifolia Chromosome: 2 Location Identifier: Mlong585_05231 Number of Introns: 2 Expression Level in Glandular Trichomes[TPM]: 1180 Homology to Canonical Genes: 90 % identity to Q947B7
MMR 1 Protein ncbiprotein:ANA95861.1 (-)-methone:(-)-menthol reductase https://www.ncbi.nlm.nih.gov/protein/1023043139 ---------MMR-L1------------ M. longifolia Chromosome: 11 Location Identifier: Mlong585_36607 Number of Introns: 6 Expression Level in Glandular Trichomes[TPM]: 107 Homology to Canonical Genes: 87 %identity to Q9XHE7
LS Protein ncbiprotein:AGN90912.1 (-)-Limonene Synthase https://www.ncbi.nlm.nih.gov/protein/511636128 ---------LS-1------------ M. longifolia Chromosome: 5 Location Identifier: Mlong585_17628 Number of Introns: 6 Expression Level in Glandular Trichomes[TPM]: 5246 Homology to Canonical Genes: 98% identity to Q40322 ---------LS-2------------ M. longifolia Chromosome: 5 Location Identifier: Mlong585_17636 Number of Introns: 6 Expression Level in Glandular Trichomes[TPM]: 5246 Homology to Canonical Genes: 98% identity to Q40322
MNR 1 Protein ncbiprotein:AAQ55959.1 (-)-Menthone:(+)-isomenthol reductase-like https://www.ncbi.nlm.nih.gov/protein/33950276 ---------MNR-L1------------ M. longifolia Chromosome: 11 Location Identifier: Mlong585_36608 Number of Introns: 0 Expression Level in Glandular Trichomes[TPM]: n/a Homology to Canonical Genes: pseudogene (premature stop codon)
L3H Protein ncbiprotein:AIS36971.1 (-)-Limonene 3-hydroxylase https://www.ncbi.nlm.nih.gov/protein/693445895 ---------L3H-1------------ M. longifolia Chromosome: 5 Location Identifier: Mlong585_17637 Number of Introns: 1 Expression Level in Glandular Trichomes[TPM]: 2281 Homology to Canonical Genes: 99 % identity to Q9XHE7 ---------L3H-2------------ M. longifolia Chromosome: 5 Location Identifier: Mlong585_17629 Number of Introns: 1 Expression Level in Glandular Trichomes[TPM]: 2281 Homology to Canonical Genes: 99 % identity to Q9XHE7 ---------L3H-3------------ M. longifolia Chromosome: 9 Location Identifier: Mlong585_30867 Number of Introns: 1 Expression Level in Glandular Trichomes[TPM]: 2475 Homology to Canonical Genes: 97 % identity to Q9XHE7 ---------L3H-4------------ M. longifolia Chromosome: 9 Location Identifier: Mlong585_30867 Number of Introns: 1 Expression Level in Glandular Trichomes[TPM]: 2475 Homology to Canonical Genes: 97 % identity to Q9XHE7
L6H Protein ncbiprotein:AAT39473.1 (-)-limonene 6-hydroxylase https://www.ncbi.nlm.nih.gov/protein/47933782
MMR 2 Protein ncbiprotein:ANA95861.1 (-)-methone:(-)-menthol reductase https://www.ncbi.nlm.nih.gov/protein/1023043139 ---------MMR-L1------------ M. longifolia Chromosome: 11 Location Identifier: Mlong585_36607 Number of Introns: 6 Expression Level in Glandular Trichomes[TPM]: 107 Homology to Canonical Genes: 87 %identity to Q9XHE7
MNR 2 Protein ncbiprotein:AAQ55959.1 (-)-Menthone:(+)-isomenthol reductase-like https://www.ncbi.nlm.nih.gov/protein/33950276 ---------MNR-L1------------ M. longifolia Chromosome: 11 Location Identifier: Mlong585_36608 Number of Introns: 0 Expression Level in Glandular Trichomes[TPM]: n/a Homology to Canonical Genes: pseudogene (premature stop codon

References

  1. Developmental regulation of monoterpene biosynthesis in the glandular trichomes of peppermint. McConkey ME, Gershenzon J, Croteau RB. Plant Physiol. 2000 Jan;122(1):215–24. PubMed Europe PMC Scholia
  2. (-)-Menthol biosynthesis and molecular genetics. Croteau RB, Davis EM, Ringer KL, Wildung MR. Naturwissenschaften. 2005 Dec;92(12):562–77. PubMed Europe PMC Scholia