Fehrhart

Thyroid hormones production and peripheral downstream signaling effects

Integrated breast cancer pathway

Dravet syndrome

Type I interferon induction and signaling during SARS-CoV-2 infection

Kallmann syndrome

NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence

Small cell lung cancer

Metabolic pathway of LDL, HDL and TG, including diseases

PCSK9-mediated LDL receptor degradation

Heterochronic gene regulation of development

Cell engulfment

Pentose phosphate metabolism

Development of ureteric derived collecting system

GDNF/RET signaling axis

COVID-19 adverse outcome pathway

Arsenic metabolism and reactive oxygen species generation

Nucleotide excision repair in xeroderma pigmentosum

Familial hyperlipidemia type 2

Neuroinflammation and glutamatergic signaling

Estradiol regulation in porto-sinusoidal vascular disease

Chromosomal and microsatellite instability in colorectal cancer

Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling

Focal adhesion

Glucocorticoid receptor pathway

3q29 copy number variation syndrome

Endoplasmic reticulum stress response in coronavirus infection

Neovascularization processes

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

Vitamin B12 metabolism

Selenium metabolism / selenoproteins

Ovarian infertility

GPR143 in melanocytes and retinal pigment epithelium cells

CAMKK2 pathway

Sudden infant death syndrome (SIDS) susceptibility pathways

Canonical and non-canonical TGF-B signaling

HIF1A and PPARG in cardiac hypertropthy

Calcium regulation in cardiac cells

MAPK pathway in congenital thyroid cancer

Ciliary landscape

ncRNAs involved in STAT3 signaling in hepatocellular carcinoma

ncRNAs in Wnt signaling in hepatocellular carcinoma

Thermogenesis

16p11.2 proximal deletion syndrome

Major receptors targeted by epinephrine and norepinephrine

Cancer immunotherapy by PD-1 blockade

MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement

Genes related to primary cilium development (based on CRISPR)

Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms

Intraflagellar transport proteins binding to dynein

Cysteine and methionine catabolism

Signal transduction through IL1R

Estrogen receptor pathway

Network map of SARS-CoV-2 signaling

Proximal tubule transport

SARS coronavirus and innate immunity

Purinergic signaling

Mammalian disorder of sexual development

NPHP1 deletion syndrome

TAR syndrome

Kleefstra syndrome

2q37 copy number variation syndrome

2q13 copy number variation syndrome

15q13.3 copy number variation syndrome

15q11.2 copy number variation syndrome

7q11.23 copy number variation syndrome

Unfolded protein response

1q21.1 copy number variation syndrome

Peroxiredoxin 2 induced ovarian failure

Regucalcin in proximal tubule epithelial kidney cells

Prader-Willi and Angelman syndrome

8q11.23 (RB1CC1) copy number variation

15q25 copy number variation

15q11q13 copy number variation

13q12.12 copy number variation

10q22q23 copy number variation

5q35 copy number variation

17p13.3 (YWHAE) copy number variation

4p16.3 copy number variation

17q12 copy number variation syndrome

Cholestasis

Bardet-Biedl syndrome

2q21.1 copy number variation syndrome

2q11.2 copy number variation syndrome

Spina bifida

Familial hyperlipidemia type 1

Meta pathway lipodystrophy, dyslipidemia and hyperlipidemia

Nephrogenesis

Complement system

Oxidative phosphorylation

Exercise-induced circadian regulation

Complement and coagulation cascades

PAFAH1B1 copy number variation

13q12 or CRYL1 copy number variation

7q11.23 distal copy number variation

6q16 copy number variation

NRXN1 deletion syndrome

Smith-Magenis and Potocki-Lupski syndrome copy number variation

NF1 copy number variation syndrome

11p11.2 copy number variation syndrome

8p23.1 copy number variation syndrome

1p36 copy number variation syndrome

Kynurenine pathway and links to cell senescence

Pentose phosphate pathway in senescent cells

SARS-CoV-2 innate immunity evasion and cell-specific immune response

Overlap between signal transduction pathways contributing to LMNA laminopathies

Influence of laminopathies on Wnt signaling

Peroxiredoxin 2 induced ovarian failure

Vitamin D-sensitive calcium signaling in depression

Joubert syndrome

FOXP3 in COVID-19

Mitochondrial immune response to SARS-CoV-2

Aspirin and miRNAs

Fragile X syndrome

Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism

Rett syndrome

Acute viral myocarditis

Purine metabolism and related disorders

Angiopoietin-like protein 8 regulatory pathway

Pluripotent stem cell differentiation pathway

Hair follicle development: cytodifferentiation - stage 3 of 3

DNA damage response (only ATM dependent)

Androgen receptor network in prostate cancer

Familial hyperlipidemia type 3

Vitamin A and carotenoid metabolism

RAC1/PAK1/p38/MMP2 pathway

Folate metabolism

Phosphodiesterases in neuronal function

Polycystic kidney disease pathway

miRNA regulation of prostate cancer signaling

Hippo signaling regulation

Pilocytic astrocytoma

ErbB signaling

IL2 signaling

MAP3K1 role in promoting and blocking gonadal determination

Netrin-UNC5B signaling

Regulatory circuits of STAT3 signaling

IL10 anti-inflammatory signaling

Wnt signaling

Corticotropin-releasing hormone signaling

Glioblastoma signaling

PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer

Prion disease pathway

Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins

STING pathway in Kawasaki-like disease and COVID-19

Lipids measured in liver metastasis from breast cancer

Modified nucleosides derived from tRNA as urinary cancer markers

Degradation pathway of sphingolipids, including diseases

MicroRNA for targeting cancer growth and vascularization in glioblastoma

Mecp2 and associated Rett syndrome

Thiamine metabolic pathways

Markers of kidney cell lineage

Selective expression of chemokine receptors during T-cell polarization

Ethanol metabolism production of ROS by CYP2E1

Ethanol metabolism resulting in production of ROS by CYP2E1

Hematopoietic stem cell differentiation

RAS and bradykinin pathways in COVID-19

Downregulation of ACE2 by SARS-CoV-2 spike protein

Physiological and pathological hypertrophy of the heart

Hypothesized pathways in pathogenesis of cardiovascular disease

Multiple epiphyseal dysplasia and pseudoachondroplasia genes

Alstrom syndrome

Envelope proteins and their potential roles in EDMD physiopathology

Effect of progerin on genes involved in progeria

Lamin A processing pathway

10q11.21q11.23 copy number variation syndrome

Kisspeptin/kisspeptin receptor system in the ovary

22q11.2 copy number variation syndrome

FABP4 in ovarian cancer

Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors

Epithelial to mesenchymal transition in colorectal cancer

miRNA regulation of p53 pathway in prostate cancer

Photodynamic therapy-induced NF-kB survival signaling

Flowering time pathway

Oxytocin signaling

Flowering time pathway

One-carbon metabolism

Host-pathogen interaction of human coronaviruses - interferon induction

Breast cancer pathway

TCA cycle nutrient use and invasiveness of ovarian cancer

4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression

Regulation of apoptosis by parathyroid hormone-related protein

Striated muscle contraction pathway

Amplification and expansion of oncogenic pathways as metastatic traits

Endometrial cancer

Alternative pathway of fetal androgen synthesis

Cholesterol biosynthesis with skeletal dysplasias

Oxysterols derived from cholesterol

Disorders of folate metabolism and transport

Bladder cancer

Riboflavin and CoQ disorders

Linoleic acid metabolism affected by SARS-CoV-2

Vitamin B6-dependent and responsive disorders

Genetic causes of porto-sinusoidal vascular disease

Acquired partial lipodystrophy / Barraquer-Simons syndrome

16p11.2 distal deletion syndrome

Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway

Biotin metabolism

miRNA targets in ECM and membrane receptors

Parkinson's disease pathway

Creatine pathway

Ethylmalonic encephalopathy

Urea cycle and associated pathways

Urea cycle and related diseases

Glycosylation and related congenital defects

Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases

Methionine metabolism leading to sulfur amino acids and related disorders

MTHFR deficiency

Vitamin B12 disorders

Krebs cycle disorders

Pyrimidine metabolism and related diseases

GABA metabolism (aka GHB)

MECP2 and associated Rett syndrome

Cholesterol synthesis disorders

Calcium mediated T-cell apoptosis involved in inclusion body myositis

Proline and hydroxyproline pathways

Cerebral organic acidurias, including diseases

Tyrosine metabolism and related disorders

Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine

Codeine and morphine metabolism

Phase I biotransformations, non-P450

Cancer immunotherapy by CTLA4 blockade

Amyotrophic lateral sclerosis (ALS)

Cholesterol biosynthesis pathway

Apoptosis modulation and signaling

KCNQ2-related epilepsies

Glycolysis and gluconeogenesis

Synaptic vesicle pathway

Alzheimer's disease and miRNA effects

Tryptophan metabolism

RIOK1 and RIOK2 in EGFR- and PI3K-mediated tumorigenesis

Glycine metabolism, including IMDs

MYD88 distinct input-output pathway

Sterol regulatory element-binding proteins (SREBP) signaling

Metapathway biotransformation Phase I and II

Non-small cell lung cancer

Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Purine metabolism

Glycolysis in senescence

Primary ovarian insufficiency

lncRNA in canonical Wnt signaling and colorectal cancer

Wnt signaling

Cell cycle

EGFR tyrosine kinase inhibitor resistance

PDGFR-beta pathway

MFAP5-mediated ovarian cancer cell motility and invasiveness

Genetic alterations of lung cancer

Nuclear receptors meta-pathway

Pre-implantation embryo

MicroRNAs in cardiomyocyte hypertrophy

Fluoropyrimidine activity

Parkinson's disease

Photosynthetic carbon reduction

Notch signaling

mRNA processing

Myometrial relaxation and contraction pathways

Intracellular trafficking of CFTR

Glycogen synthesis and degradation

Serotonin HTR1 group and FOS pathway

Serotonin receptor 2 and STAT3 signaling

Osteoclast signaling

Inclusion body myositis

Fatty acid biosynthesis

Fatty acid biosynthesis

Leukotriene metabolic pathway

GDNF/RET signaling axis

Primary carbon metabolism

Translation factors

mRNA processing

Ethanol effects on histone modifications

TCA cycle in senescence

Pregnane X receptor pathway

Myometrial relaxation and contraction pathways

mRNA processing

COVID-19, thrombosis and anticoagulation

Overview of nanoparticle effects

Retinoblastoma gene in cancer

Allograft rejection

Leukocyte-intrinsic Hippo pathway functions

DNA IR-damage and cellular response via ATR

Melatonin metabolism and effects

SARS-CoV-2 and ACE2 receptor: molecular mechanisms

LDLRAD4 and what we know about it

SARS-CoV-2 and COVID-19 pathway

Photodynamic therapy-induced AP-1 survival signaling

Serine metabolism

nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell

Male infertility

Parkin-ubiquitin proteasomal system pathway

Vitamin D receptor pathway

Tryptophan metabolism

Hereditary leiomyomatosis and renal cell carcinoma pathway

Host-pathogen interaction of human coronaviruses - MAPK signaling

Arrhythmogenic right ventricular cardiomyopathy

Progeria-associated lipodystrophy

Congenital generalized lipodystrophy

Genes controlling nephrogenesis

Distal convoluted tubule 1 (DCT1) cell

Ovarian infertility

SARS-CoV-2 altering angiogenesis via NRP1

Flowering time pathway

Polar auxin transport

Fatty acid beta-oxidation 3

Fatty acid beta-oxidation 2

Glycogen metabolism

Mevalonate arm of cholesterol biosynthesis pathway

ERK1-ERK2 MAPK cascade

Cannabinoid receptor signaling

Lung fibrosis

FGF signaling pathway

Sphingolipid pathway

Pentose phosphate pathway

Deregulation of Rab and Rab effector genes in bladder cancer

Nitric oxide metabolism in cystic fibrosis

Prostaglandin synthesis and regulation

Electron transport chain

Acetylcholine synthesis

GPCRs, orphan

Endochondral ossification

Conversion of angiotensinogen to angiotensin II

Neural crest cell migration in cancer

lncRNA-mediated mechanisms of therapeutic resistance

Interactions between LOXL4 and oxidative stress pathway

Metabolism of dichloroethylene by CYP450

Biochemical pathways: part I

Circadian rhythm genes

Constitutive androstane receptor pathway

Diclofenac metabolic pathway

Gastric cancer network 2

Gastric cancer network 1

Deregulation of Rab and Rab effector genes in bladder cancer

Osteoblast signaling

Monoterpene biosynthesis pathway in mint

Fluoropyrimidine activity

TCA cycle nutrient use and invasiveness of ovarian cancer

Thyroid stimulating hormone (TSH) signaling pathway

Gastric cancer network 1

Polar auxin transport

Glyoxylate, anapleurotic and succinyl CoA (GAS) pathway

Tryptophan degradation

Phenylalanine, tyrosine, and tryptophan biosynthesis

P-cymene degradation

Toll, IMD, JAK/STAT pathways for immune response to pathogens

Polyol pathway

GPR40 pathway

miRNA biogenesis

Focal adhesion

Oxidative stress response

Acetylcholine synthesis

Ectoderm differentiation

FOXA2 pathway

Host-pathogen interaction of human coronaviruses - apoptosis

Host-pathogen interaction of human coronaviruses - autophagy

One-carbon metabolism

Metabolism overview

Retinoblastoma gene in cancer

Disruption of postsynaptic signaling by CNV

Somatic sex determination

BMP2-WNT4-FOXO1 pathway in primary endometrial stromal cell differentiation

Phytochrome signaling pathway to turn on photomorphogenesis

Oxytocin signaling

Farnesoid X receptor pathway

PPAR-alpha pathway

Liver X receptor pathway

Endoderm differentiation

Alzheimer's disease

TGF-beta signaling pathway

Lung fibrosis

Amino acid conjugation of benzoic acid

Splicing factor NOVA regulated synaptic proteins

Nanomaterial induced apoptosis

ErbB signaling pathway

ErbB signaling pathway

Tumor suppressor activity of SMARCB1

Corticotropin-releasing hormone

Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer

mir-193a and MVP in colon cancer metastasis

miR-509-3p alteration of YAP1/ECM axis

Tamoxifen metabolism

Apoptosis-related network due to altered Notch3 in ovarian cancer

Apoptosis-related network due to altered Notch3 in ovarian cancer

Polyol pathway

Ethanol metabolism resulting in production of ROS by CYP2E1

Valproic acid pathway

Cytosine methylation

PPAR signaling pathway

NRF2 pathway

Photodynamic therapy-induced HIF-1 survival signaling

Photodynamic therapy-induced unfolded protein response

mRNA, protein, and metabolite inducation pathway by cyclosporin A

Septum site determination

Tryptophan metabolism

Polyol pathway

Oxidative phosphorylation

Polyol pathway

Polyol pathway

Polyol pathway

Tryptophan metabolism

Transcription factor regulation in adipogenesis

miRNAs and TFs in iPS Cell Generation

Mismatch repair

Tryptophan metabolism

Nanoparticle triggered autophagic cell death

Glyoxylate cycle

Sleep regulation

p53 signaling

Peptide GPCRs