miRNAs and TFs in iPS Cell Generation (WP2375)

Mus musculus

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This pathway describes how a set of miRNA is responsible for different steps of induced pluripotent stem cell generation in a mouse embryonic fibroblasts cell model, infected with Oct3/4, Sox2, Klf4 and c-Myc.

Authors

Susan Coort , Elisa Cirillo , Martina Summer-Kutmon , and Friederike Ehrhart

Activity

last edited

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Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

regulatory pathway

Participants

Label Type Compact URI Comment
Phf5a GeneProduct ncbigene:68479
Prpf4 GeneProduct ncbigene:70052
Snrpa GeneProduct ncbigene:53607
Bat1a GeneProduct ncbigene:53817
Oct4 GeneProduct ncbigene:18999
Sox2 GeneProduct ncbigene:20674
Sf3a3 GeneProduct ncbigene:75062

References

  1. Synergetic cooperation of microRNAs with transcription factors in iPS cell generation. Chen J, Wang G, Lu C, Guo X, Hong W, Kang J, et al. PLoS One. 2012;7(7):e40849. PubMed Europe PMC Scholia