Fatty acid beta-oxidation (WP143)

Homo sapiens

Complete fatty acid beta-oxidation pathway for saturated and unsaturated fatty acids. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP143 CPTAC Assay Portal]

Authors

Michiel Adriaens , Chris Evelo , Susan Coort , Patrick Ahles , Ferry Jagers , Adrien Defay , Alex Pico , Egon Willighagen , Martina Summer-Kutmon , Denise Slenter , Priyanka K , Kristina Hanspers , Licong , and Eric Weitz

Activity

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Cited In

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Organisms

Homo sapiens

Communities

CPTAC Lipids and LIPID MAPS

Annotations

Pathway Ontology

fatty acid degradation pathway fatty acid metabolic pathway fatty acid beta degradation pathway

Disease Ontology

lipid metabolism disorder

Participants

Label Type Compact URI Comment
trans,cis-Lauro-2,6-dienoyl-CoA Metabolite chebi:28387
3-Oxododexanoyl-CoA Metabolite pubchem.compound:11966169
Fatty Acid Metabolite chebi:35366
Glutarate Metabolite pubchem.compound:743
Trans-Oct-2-enoyl-CoA Metabolite chebi:27537
Myristoyl-CoA Metabolite chebi:15532
(S)-3-Hydroxytetradecanoyl-CoA Metabolite chebi:27466
Acetyl-CoA Metabolite cas:72-89-9
Glutaryl-CoA Metabolite chebi:15524
Glyceraldehyde-3-Phosphate Metabolite cas:591-57-1
2-trans-dodecenoyl-CoA Metabolite chebi:15471
Glycerol Metabolite cas:56-81-5
cis,cis-3,6-Dodecadienoyl-CoA Metabolite chebi:28002
Trans-Dec-2-enoyl-CoA Metabolite chebi:10723
3-Oxo-octanoyl-CoA Metabolite chebi:28264
3-Oxohexanoyl-CoA Metabolite chebi:27648
2-trans-4-cis-decadienoyl-CoA Metabolite chebi:29119
Butanoyl-CoA Metabolite chebi:15517
Decanoyl-CoA Metabolite chebi:28493
Linoleoyl-CoA Metabolite cas:40757-80-0
3-Oxopalmitoyl-CoA Metabolite chebi:15491
Dihydroxyacetone Phosphate Metabolite cas:57-04-5
Trans-Hex-2-enoyl-CoA Metabolite chebi:28706
(S)-3-Hydroxyhexadecanoyl-CoA Metabolite chebi:27402
(S)-3-Hydroxybutanoyl-CoA Metabolite chebi:15453
Lauroyl-CoA Metabolite cas:6244-92-4
Hexanoyl-CoA Metabolite chebi:27540
L-Glycerol-3-Phosphate Metabolite chebi:15978
Acyl-CoA Metabolite chebi:17984
(S)-3-Hydroxydecanoyl-CoA Metabolite chebi:28325
(S)-3-Hydroxyoctanoyl-CoA Metabolite chebi:28632
Palmitoyl-CoA Metabolite chebi:15525
Acetoacetyl-CoA Metabolite cas:1420-36-6
3-trans-decenoyl-CoA Metabolite chebi:29126
Triacylglycerol Metabolite chebi:17855
HADHA GeneProduct ncbigene:3030
ACADM GeneProduct ncbigene:34
HADHB GeneProduct ncbigene:3032
PNPLA2 GeneProduct ncbigene:57104
CPT2 GeneProduct ncbigene:1376
ACADS GeneProduct ncbigene:35
DCI GeneProduct ncbigene:1632
ECHS1 GeneProduct ncbigene:1892
GCDH GeneProduct ncbigene:2639
HADHSC GeneProduct ncbigene:3033
ACADVL GeneProduct ncbigene:37
GPD2 GeneProduct ncbigene:2820
ACSL5 GeneProduct ncbigene:51703
DLD GeneProduct ncbigene:1738
ACAS2 GeneProduct ncbigene:55902
TPI1 GeneProduct ncbigene:7167
GK2 GeneProduct ncbigene:2712
ACSL1 GeneProduct ncbigene:2180
DECR1 GeneProduct ncbigene:1666
LIPC GeneProduct ncbigene:3990
SLC25A20 GeneProduct ncbigene:788
ACADL GeneProduct ncbigene:33
CRAT GeneProduct ncbigene:1384
LIPE GeneProduct ncbigene:3991
ACSL6 GeneProduct ncbigene:23305
CPT1A GeneProduct ncbigene:1374
CPT1B GeneProduct ncbigene:1375
ACSL4 GeneProduct ncbigene:2182
GK GeneProduct ncbigene:2710
LIPF GeneProduct ncbigene:8513
CHKB GeneProduct ncbigene:1120
ACAT1 GeneProduct ncbigene:38
ACSL3 GeneProduct ncbigene:2181
LPL GeneProduct ncbigene:4023

References