Metabolic reprogramming in colon cancer (WP4290)

Homo sapiens

Authors

Kristina Hanspers , Egon Willighagen , and Alex Pico

Activity

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Cited In

• Ten simple rules for creating reusable pathway models for computational analysis and visualization (2021).
• The double dealing of cyclin D1 (2020).
• Investigation of the relationship between COVID-19 and pancreatic cancer using bioinformatics and systems biology approaches (2024).

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Organisms

Homo sapiens

Communities

CPTAC Diseases Serious Request 2024 - MetaKids

Annotations

Disease Ontology

colorectal cancer

Pathway Ontology

cancer pathway altered carbohydrate metabolic pathway

References

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2. Citrate synthesis in intact rat-liver mitochondria is irreversible. Greksák M, Lopes-Cardozo M, van den Bergh SG. Eur J Biochem. 1982 Feb;122(2):423–7. PubMed Europe PMC Scholia
3. Isotopomer analysis of citric acid cycle and gluconeogenesis in rat liver. Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis. Des Rosiers C, Di Donato L, Comte B, Laplante A, Marcoux C, David F, et al. J Biol Chem. 1995 Apr 28;270(17):10027–36. PubMed Europe PMC Scholia
4. Modeling of liver citric acid cycle and gluconeogenesis based on 13C mass isotopomer distribution analysis of intermediates. Fernandez CA, Des Rosiers C. J Biol Chem. 1995 Apr 28;270(17):10037–42. PubMed Europe PMC Scholia
5. Characterization of the ATP- and GTP-specific succinyl-CoA synthetases in pigeon. The enzymes incorporate the same alpha-subunit. Johnson JD, Muhonen WW, Lambeth DO. J Biol Chem. 1998 Oct 16;273(42):27573–9. PubMed Europe PMC Scholia
6. The alpha-ketoglutarate dehydrogenase complex. Sheu KF, Blass JP. Ann N Y Acad Sci. 1999;893:61–78. PubMed Europe PMC Scholia
7. The conversion of citrate into cis-aconitate and isocitrate in the presence of aconitase. KREBS HA, HOLZACH O. Biochem J. 1952 Nov;52(3):527–8. PubMed Europe PMC Scholia