MicroRNA for targeting cancer growth and vascularization in glioblastoma (WP3593)

Homo sapiens

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miR-148a and miR-31 target the factor inhibiting hypoxia (FIH1) to promote downstream HIF1α and Notch signaling

Authors

Kristina Hanspers , Ryan Miller , Alex Pico , Friederike Ehrhart , Eric Weitz , and Martina Summer-Kutmon

Activity

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Cited In

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Organisms

Homo sapiens

Communities

CPTAC ExRNA

Annotations

Disease Ontology

glioblastoma

Pathway Ontology

cancer pathway disease pathway glioma pathway microRNA pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
HES1 GeneProduct ensembl:ENSG00000114315
MIR31 GeneProduct mirbase:MI0000089
VEGFA GeneProduct ensembl:ENSG00000112715
HIF1AN GeneProduct ensembl:ENSG00000166135
HEY1 GeneProduct ensembl:ENSG00000164683
HIF1A GeneProduct ensembl:ENSG00000100644
VEGFB GeneProduct ensembl:ENSG00000173511
VEGFC GeneProduct ensembl:ENSG00000150630

References

  1. The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma. Wong HKA, Fatimy RE, Onodera C, Wei Z, Yi M, Mohan A, et al. Mol Ther. 2015 Jul;23(7):1234–47. PubMed Europe PMC Scholia