Photodynamic therapy-induced HIF-1 survival signaling (WP3614)

Homo sapiens

Authors

Ruud Weijer , Kristina Hanspers , Friederike Ehrhart , Martina Summer-Kutmon , and Eric Weitz

Activity

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Cited In

• Identification of biomarkers and pathways for the SARS-CoV-2 infections that make complexities in pulmonary arterial hypertension patients (2021).
• Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC‐derived osteoblasts from Thoroughbred horses (2025).
• Demonstration of the impact of COVID-19 on metabolic associated fatty liver disease by bioinformatics and system biology approach (2023).

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Organisms

Homo sapiens

Communities

CPTAC

Annotations

Disease Ontology

cancer

Pathway Ontology

altered regulatory pathway

References

1. Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies. Broekgaarden M, Weijer R, van Gulik TM, Hamblin MR, Heger M. Cancer Metastasis Rev. 2015 Dec;34(4):643–90. PubMed Europe PMC Scholia
2. Low-power photodynamic therapy induces survival signaling in perihilar cholangiocarcinoma cells. Weijer R, Broekgaarden M, van Golen RF, Bulle E, Nieuwenhuis E, Jongejan A, et al. BMC Cancer. 2015 Dec 26;15:1014. PubMed Europe PMC Scholia