Fatty acid transporters (WP5061)

Homo sapiens

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Long chain fatty acid (LCFA) transporters in different tissues

Authors

Jeroen Kearns , Egon Willighagen , and Eric Weitz

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Cell Type Ontology

hepatocyte fat cell kidney cell cardiocyte

Pathway Ontology

transport pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
COENZYME A Metabolite chebi:15346
LCFAs Metabolite chebi:15904
ACSBG1 GeneProduct ensembl:ENSG00000103740
SLC27A6 GeneProduct hgnc.symbol:HGNC:11000
ACSL1 GeneProduct ensembl:ENSG00000151726
CD36 GeneProduct ensembl:ENSG00000135218
SLC27A2 GeneProduct hgnc.symbol:HGNC:10996
ACSL6 GeneProduct ensembl:ENSG00000164398
FABP4 GeneProduct ensembl:ENSG00000170323
FABP1 GeneProduct ensembl:ENSG00000163586
FABP5 GeneProduct ensembl:ENSG00000164687
ACSL4 GeneProduct ensembl:ENSG00000068366
FABP3 GeneProduct ensembl:ENSG00000121769
ACSL3 GeneProduct ensembl:ENSG00000123983
SLC27A4 GeneProduct hgnc.symbol:SLC27A4
FABP7 GeneProduct ensembl:ENSG00000164434
DBI GeneProduct ensembl:ENSG00000155368
FABP9 GeneProduct ensembl:ENSG00000205186
FABP2 GeneProduct ensembl:ENSG00000145384
SLC27A5 GeneProduct hgnc.symbol:HGNC:10999
FABP1 GeneProduct hgnc.symbol:HGNC:3555
SLC27A3 GeneProduct hgnc.symbol:HGNC:10997
SLC27A1 GeneProduct hgnc.symbol:HGNC:10995
ACSL5 GeneProduct ensembl:ENSG00000197142
SLC27A4 GeneProduct ensembl:ENSG00000167114
ACSBG2 GeneProduct ensembl:ENSG00000130377
FABP6 GeneProduct ensembl:ENSG00000170231

References

  1. Expression of fatty-acid-binding proteins in cells involved in lung-specific lipid metabolism. Guthmann F, Hohoff C, Fechner H, Humbert P, Börchers T, Spener F, et al. Eur J Biochem. 1998 Apr 15;253(2):430–6. PubMed Europe PMC Scholia
  2. Insights into binding of fatty acids by fatty acid binding proteins. Hanhoff T, Lücke C, Spener F. Mol Cell Biochem. 2002 Oct;239(1–2):45–54. PubMed Europe PMC Scholia
  3. A current review of fatty acid transport proteins (SLC27). Stahl A. Pflugers Arch. 2004 Feb;447(5):722–7. PubMed Europe PMC Scholia
  4. The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism. Chmurzyńska A. J Appl Genet. 2006;47(1):39–48. PubMed Europe PMC Scholia
  5. Long-chain acyl-CoA synthetases and fatty acid channeling. Mashek DG, Li LO, Coleman RA. Future Lipidol. 2007 Aug;2(4):465–76. PubMed Europe PMC Scholia
  6. The human fatty acid-binding protein family: evolutionary divergences and functions. Smathers RL, Petersen DR. Hum Genomics. 2011 Mar;5(3):170–91. PubMed Europe PMC Scholia
  7. Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis. Padanad MS, Konstantinidou G, Venkateswaran N, Melegari M, Rindhe S, Mitsche M, et al. Cell Rep. 2016 Aug 9;16(6):1614–28. PubMed Europe PMC Scholia