Mitochondrial complex I inhibition leading to chemical-induced Fanconi syndrome (WP4944)

Homo sapiens

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This pathway is a meta-pathway that represents an updated version of the Adverse Outcome Pathway 276: Inhibition of complex I of the electron transport chain leading to chemical induced Fanconi syndrome (https://aopwiki.org/aops/276). All Key Events are present as Key Event nodes, with their corresponding molecular pathways as pathway nodes.

Authors

Marvin Martens , Egon Willighagen , Eric Weitz , Finterly Hu , and Martina Summer-Kutmon

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Adverse Outcome Pathways

Annotations

Pathway Ontology

altered metabolic pathway disease pathway

Disease Ontology

Fanconi syndrome

Participants

Label Type Compact URI Comment
Deguelin Metabolite chebi:4357

References