Polar auxin transport (WP2941)

Arabidopsis thaliana

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Polar auxin transport pathway of Arabidopsis. Even though we have shown a representative diagram of influx and efflux proteins on different but adjacent cells, the auxin influx and efflux transport proteins when present in the same cell, are often located in the plasma membrane of cell's opposite side or on the sides (left/right). All the different paralogs of influx and efflux proteins may not be present in the same cell. Often their expression and localization is tissue, cell, organ and development stage specific. This helps in directing the flow of auxin towards 'auxin maxima' sites in plant organs and cells as needed. In some cases auxin can permeate through the plasma membrane. The Arabidopsis gene products PIN5, PIN6 and PIN8 were removed from the pathway since they are known to be involved in intracellular auxin transport rather than the intercellular auxin transport.

Authors

Pankaj Jaiswal , Kristina Hanspers , Friederike Ehrhart , Eric Weitz , Finterly Hu , and Egon Willighagen

Activity

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Organisms

Arabidopsis thaliana

Communities

Annotations

Pathway Ontology

hormone signaling pathway transport pathway

Participants

Label Type Compact URI Comment
H+ Metabolite chebi:24636 Synonym: proton
indole-3-acetic acid Metabolite chebi:16411 Synonym: IAA
indole-3-acetate Metabolite chebi:30854 Synonym: IAA(-) ion
(H+)x2 Metabolite chebi:24636 Synonym: proton
PIN3 GeneProduct ensembl:AT1G23080 Auxin efflux carrier family protein
PIN2 GeneProduct ensembl:AT5G57090 Auxin efflux carrier family protein
PIN4 GeneProduct ensembl:AT5G15100 Auxin efflux carrier family protein
PIN1 GeneProduct ensembl:AT1G73590 Auxin efflux carrier family protein
PIN7 GeneProduct ensembl:AT1G70940 Auxin efflux carrier family protein
LAX1 GeneProduct ensembl:AT5G01240 Auxin influx transporter
LAX3 GeneProduct ensembl:AT1G77690 Auxin influx transporter
LAX2 GeneProduct ensembl:AT2G21050 Auxin influx transporter
AUX1 GeneProduct ensembl:AT2G38120 Auxin influx transporter

References

  1. AtPIN2 defines a locus of Arabidopsis for root gravitropism control. Müller A, Guan C, Gälweiler L, Tänzler P, Huijser P, Marchant A, et al. EMBO J. 1998 Dec 1;17(23):6903–11. PubMed Europe PMC Scholia
  2. Auxin Polar Transport Is Essential for the Establishment of Bilateral Symmetry during Early Plant Embryogenesis. Liu Cm, Xu Zh, Chua NH. Plant Cell. 1993 Jun;5(6):621–30. PubMed Europe PMC Scholia
  3. Requirement of the Auxin Polar Transport System in Early Stages of Arabidopsis Floral Bud Formation. Okada K, Ueda J, Komaki MK, Bell CJ, Shimura Y. Plant Cell. 1991 Jul;3(7):677–84. PubMed Europe PMC Scholia
  4. High-affinity auxin transport by the AUX1 influx carrier protein. Yang Y, Hammes UZ, Taylor CG, Schachtman DP, Nielsen E. Curr Biol. 2006 Jun 6;16(11):1123–7. PubMed Europe PMC Scholia
  5. Vectorial information for Arabidopsis planar polarity is mediated by combined AUX1, EIN2, and GNOM activity. Fischer U, Ikeda Y, Ljung K, Serralbo O, Singh M, Heidstra R, et al. Curr Biol. 2006 Nov 7;16(21):2143–9. PubMed Europe PMC Scholia
  6. Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1. Kleine-Vehn J, Dhonukshe P, Swarup R, Bennett M, Friml J. Plant Cell. 2006 Nov;18(11):3171–81. PubMed Europe PMC Scholia
  7. Subcellular homeostasis of phytohormone auxin is mediated by the ER-localized PIN5 transporter. Mravec J, Skůpa P, Bailly A, Hoyerová K, Krecek P, Bielach A, et al. Nature. 2009 Jun 25;459(7250):1136–40. PubMed Europe PMC Scholia
  8. Abscisic acid represses growth of the Arabidopsis embryonic axis after germination by enhancing auxin signaling. Belin C, Megies C, Hauserová E, Lopez-Molina L. Plant Cell. 2009 Aug;21(8):2253–68. PubMed Europe PMC Scholia
  9. ER-localized auxin transporter PIN8 regulates auxin homeostasis and male gametophyte development in Arabidopsis. Ding Z, Wang B, Moreno I, Dupláková N, Simon S, Carraro N, et al. Nat Commun. 2012 Jul 3;3:941. PubMed Europe PMC Scholia
  10. Patterning of leaf vein networks by convergent auxin transport pathways. Sawchuk MG, Edgar A, Scarpella E. PLoS Genet. 2013;9(2):e1003294. PubMed Europe PMC Scholia
  11. PIN6 is required for nectary auxin response and short stamen development. Bender RL, Fekete ML, Klinkenberg PM, Hampton M, Bauer B, Malecha M, et al. Plant J. 2013 Jun;74(6):893–904. PubMed Europe PMC Scholia
  12. Auxin and strigolactone signaling are required for modulation of Arabidopsis shoot branching by nitrogen supply. de Jong M, George G, Ongaro V, Williamson L, Willetts B, Ljung K, et al. Plant Physiol. 2014 Sep;166(1):384–95. PubMed Europe PMC Scholia
  13. PIN proteins and the evolution of plant development. Bennett T. Trends Plant Sci. 2015 Aug;20(8):498–507. PubMed Europe PMC Scholia