Biogenic amine synthesis (WP125)

Drosophila melanogaster

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Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html

Authors

Alex Pico , Thomas Kelder , Egon Willighagen , Christine Chichester , Martina Summer-Kutmon , Krasin , Elisson nl , Eric Weitz , and Kristina Hanspers

Activity

last edited

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Organisms

Drosophila melanogaster

Communities

Annotations

Pathway Ontology

biogenic amine biosynthetic pathway

Participants

Label Type Compact URI Comment
Epinephrine Metabolite hmdb:HMDB00068
Dopamine Metabolite hmdb:HMDB00073
Tyrosine Metabolite chebi:17895
Norepinephrine Metabolite hmdb:HMDB00216
Histidine Metabolite hmdb:HMDB00177
GABA Metabolite chebi:16865
Phenylalanine Metabolite chebi:17295
Glutamate Metabolite chebi:14321
Choline Metabolite hmdb:HMDB00097
Acetylserotonin Metabolite hmdb:HMDB01238
Histamine Metabolite hmdb:HMDB00870
L-Dopa Metabolite hmdb:HMDB00181
Acetylcholine Metabolite hmdb:HMDB00895
Tryptophan Metabolite hmdb:HMDB00929
Melatonin Metabolite hmdb:HMDB01389
Serotonin Metabolite hmdb:HMDB00259
5-Hydroxy-L-tryptophan Metabolite hmdb:HMDB00472
ACHE GeneProduct ensembl:ENSG00000087085
Ddc GeneProduct ncbigene:35190
Trh GeneProduct ncbigene:38121
PNMT GeneProduct ensembl:ENSG00000141744
Hn GeneProduct ncbigene:38871
ple GeneProduct ncbigene:38746
Tbh GeneProduct ncbigene:31718
Hdc GeneProduct ncbigene:36076
AANAT GeneProduct ensembl:ENSG00000129673
GAD2 GeneProduct ensembl:ENSG00000136750
MAOA GeneProduct ensembl:ENSG00000189221
ASMT GeneProduct ensembl:ENSG00000196433
Cha GeneProduct ncbigene:42249
Gad1 GeneProduct ncbigene:38484
COMT GeneProduct ncbigene:47091

References

  1. Neuroscience [Internet]. Purves D. Sinauer Associates Incorporated; 2001. 709 p. Available from: https://books.google.com/books/about/Neuroscience.html?hl=&id=t9iGQgAACAAJ OpenLibrary Worldcat