G protein signaling pathways (WP813)

Gallus gallus

Open in new tab Open in Newt (SBGN)
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
G proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades. G proteins are so called because they function as "molecular switches". They alternate from 'inactive' guanosine diphosphate (GDP) to 'active' guanosine triphosphate (GTP), which is a binding state, and which proceeds to regulate downstream cell processes. Source: [[wikipedia:G_protein|Wikipedia]]

Authors

Thomas Kelder , Christine Chichester , Lauren J. Dupuis , and Eric Weitz

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Gallus gallus

Communities

Annotations

Pathway Ontology

G protein mediated signaling pathway

Participants

Label Type Compact URI Comment
IP3 Metabolite hmdb:HMDB0001143
Ca2+ Metabolite hmdb:HMDB0000464
DAG Metabolite kegg.compound:C00165
cAMP Metabolite hmdb:HMDB0000058
PRKAR2B GeneProduct ncbigene:769420
GNG10 GeneProduct ncbigene:769603
PDE7B GeneProduct ncbigene:421692
ADCY3 GeneProduct ncbigene:422013
ADCY5 GeneProduct ncbigene:395340
GNG12 GeneProduct ncbigene:772239
GNG11 GeneProduct ncbigene:771999
AKAP8 GeneProduct ncbigene:426167
AKAP1 GeneProduct ncbigene:417668
PRKAR1B GeneProduct ncbigene:416446
GNAS GeneProduct ncbigene:419313
PRKCD GeneProduct ncbigene:415905
GNB3 GeneProduct ncbigene:427945
RCJMB04_23b22 GeneProduct ncbigene:427262
GNAO1 GeneProduct ncbigene:415698
PRKCB GeneProduct ncbigene:416567
GNA14 GeneProduct ncbigene:431611
AKAP5 GeneProduct ncbigene:428917
GNAZ GeneProduct ncbigene:770226
PDE8B GeneProduct ncbigene:427645
NRAS GeneProduct ncbigene:419885
GNG13 GeneProduct ncbigene:771014
PRKAR1A GeneProduct ncbigene:417438
GNA11 GeneProduct ncbigene:374077
PRKCH GeneProduct ncbigene:423518
PPP3CA GeneProduct ncbigene:395113
GNAI1 GeneProduct ncbigene:396368
CALM1 GeneProduct ncbigene:396523
PRKACB GeneProduct ncbigene:424542
PRKAR2A GeneProduct ncbigene:416062
GNB5 GeneProduct ncbigene:415417
KCNJ3 GeneProduct ncbigene:396369
AKAP7 GeneProduct ncbigene:426926
GNA13 GeneProduct ncbigene:417434
PDE1A GeneProduct ncbigene:424116
PDE1C GeneProduct ncbigene:420752
ADCY2 GeneProduct ncbigene:420935
GNAL GeneProduct ncbigene:474379
RCJMB04_12k21 GeneProduct ncbigene:423302
PRKD3 GeneProduct ncbigene:421478
ADCY9 GeneProduct ncbigene:395339
AKAP6 GeneProduct ncbigene:423314
ADCY1 GeneProduct ncbigene:420788
AKAP13 GeneProduct ncbigene:415502
PDE8A GeneProduct ncbigene:415455
AKAP12 GeneProduct ncbigene:421634
RHOA GeneProduct ncbigene:395442
GNAI3 GeneProduct ncbigene:374097
AKAP11 GeneProduct ncbigene:418835
PRKCE GeneProduct ncbigene:421409
RCJMB04_6n13 GeneProduct ncbigene:419402
RCJMB04_5a10 GeneProduct ncbigene:417430
RCJMB04_16p24 GeneProduct ncbigene:424991
GNG5 GeneProduct ncbigene:424538
HRAS GeneProduct ncbigene:396229
PRKCZ GeneProduct ncbigene:419399
AKAP10 GeneProduct ncbigene:417612
ADCY8 GeneProduct ncbigene:420328
ADCY7 GeneProduct ncbigene:415732
PDE4B GeneProduct ncbigene:424700
KRAS GeneProduct ncbigene:418207
PDE7A GeneProduct ncbigene:425199
AKAP9 GeneProduct ncbigene:395695
GNG4 GeneProduct ncbigene:771582
GNA12 GeneProduct ncbigene:769924
ITPR1 GeneProduct ncbigene:395412
SLC9A1 GeneProduct ncbigene:419580
GNAI2 GeneProduct ncbigene:396367

References

  1. G proteins: a family of signal transducers. Stryer L, Bourne HR. Annu Rev Cell Biol. 1986;2:391–419. PubMed Europe PMC Scholia
  2. G protein pathways. Neves SR, Ram PT, Iyengar R. Science. 2002 May 31;296(5573):1636–9. PubMed Europe PMC Scholia