Asparagine biosynthesis (WP67)
Saccharomyces cerevisiae
The precursor to asparagine is oxaloacetate, which the AAT enzyme converts to aspartate by transferring the amino group from glutamate to oxaloacetate, producing α-ketoglutarate and aspartate. The enzyme ASN produces asparagine, AMP, glutamate, and pyrophosphate from aspartate, glutamine, and ATP. Description adapted from [https://en.wikipedia.org/wiki/Asparagine Wikipedia].
Authors
Meredith Braymer , Martina Summer-Kutmon , Egon Willighagen , Christine Chichester , Eric Weitz , and Kristina HanspersActivity
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Organisms
Saccharomyces cerevisiaeCommunities
Annotations
Pathway Ontology
asparagine metabolic pathway classic metabolic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| L-asparagine | Metabolite | cas:70-47-3 | |
| L-aspartate | Metabolite | chebi:29991 | |
| Oxaloacetic acid | Metabolite | chebi:30744 | |
| pyrophosphate | Metabolite | cas:2466-09-3 | |
| ATP | Metabolite | cas:1927-31-7 | |
| H2O | Metabolite | hmdb:HMDB02111 | |
| L-glutamate | Metabolite | cas:56-86-0 | |
| 2-oxoglutarate | Metabolite | chebi:16810 | |
| AMP | Metabolite | chebi:16027 | |
| L-glutamine | Metabolite | cas:56-85-9 | |
| AAT1 | GeneProduct | sgd:S000001589 | |
| ASN2 | GeneProduct | sgd:S000003356 | |
| AAT2 | GeneProduct | sgd:S000004017 | |
| ASN1 | GeneProduct | sgd:S000006349 |