Glycerolipids and glycerophospholipids (WP4345)

Mus musculus

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This pathway is inspired by the Lipidmaps>Glycerolipids and Glycerophospholipids Pathways expended pathway display [https://lipidmaps.org/pathway/pathways_maps]. Glycerolipids are composed of mono-, di-, and tri-substituted glycerols, which all function as energy storage. Glycerophospholipids are also based on glycerol phospholipids, and serve as the main component of biological membranes.

Authors

Eoin Fahy , Ryan Miller , Egon Willighagen , Denise Slenter , Eric Weitz , and Conroy lipids

Activity

last edited

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Organisms

Mus musculus

Communities

Lipids and LIPID MAPS

Annotations

Pathway Ontology

glycerophospholipid metabolic pathway glycerolipid metabolic pathway

Participants

Label Type Compact URI Comment
CoA(16:0) Metabolite cas:1763-10-6 AKA 'Coenzyme A, S-​hexadecanoate'
CoA Metabolite chebi:15346
PA Metabolite lipidmaps:LMGP10010000 aka phosphatidic acid
Glycerol-3-P Metabolite pubchem.compound:439162
1-acyl-LPA Metabolite lipidmaps:LMGP10050000 aka 1-acyl-sn-glycero-3-phosphate , 1-acylglycerophosphate, lysophosphatic acid
Choline Metabolite pubchem.compound:305
CDP-Etn Metabolite pubchem.compound:123727
PE Metabolite lipidmaps:LMGP02010000
Acyl-CoA Metabolite lipidmaps:LMFA07050000
DAG Metabolite lipidmaps:LMGL02010000
CDP-DAG Metabolite lipidmaps:LMGP13010000
PGP Metabolite lipidmaps:LMGP05010000
PG Metabolite lipidmaps:LMGP04010000
CL Metabolite lipidmaps:LMGP12010000
PI Metabolite lipidmaps:LMGP06010000
PC Metabolite lipidmaps:LMGP01010000
Choline-P Metabolite pubchem.compound:135437
CDP-Choline Metabolite pubchem.compound:13804
PS Metabolite lipidmaps:LMGP03010000
1-acyl-LPC Metabolite lipidmaps:LMGP01050000
PE-Me Metabolite lipidmaps:LMGP0201AA00
PE-Me2 Metabolite lipidmaps:LMGP0201AB00
Etn-P Metabolite pubchem.compound:1015
Etn Metabolite pubchem.compound:700
TAG Metabolite lipidmaps:LMGL03010000
2-acyl-PA Metabolite lipidmaps:LMGP1005AA00
1-acyl-PE Metabolite lipidmaps:LMGP02050000
CoA(18:0) Metabolite cas:362-66-3 AKA 'Coenzyme A, S-​octadecanoate'
CoA(20:0) Metabolite cas:15895-27-9 AKA 'Coenzyme A, S-​eicosanoate'
LPG Metabolite lipidmaps:LMGP04050000 AKA 'Lysyl-phosphatidylglycerol' (not part of LipidMaps ontology)
LPI Metabolite lipidmaps:LMGP06050000 AKA 'Lysophosphatidylinositol' (not part of LipidMaps ontology)
LPC Metabolite lipidmaps:LMGP01050000 AKA '1-acyl-sn-glycero-3-phosphocholine'
LPS Metabolite lipidmaps:LMGP03050000 AKA '1-acyl-sn-glycero-3-phospho-serine',(not part of LipidMaps ontology)
LPE Metabolite lipidmaps:LMGP02050000 AKA '1-acyl-sn-glycero-3-phosphoethanolamine'
Gpam GeneProduct ncbigene:14732
PPap2a GeneProduct ncbigene:19012
Crls1 GeneProduct ncbigene:66586
Chpt1 GeneProduct ncbigene:212862
Pcyt2 GeneProduct ncbigene:68671
Cds1 GeneProduct ncbigene:74596
Pisd GeneProduct ncbigene:320951
Dgat1 GeneProduct ncbigene:13350
Ptdss2 GeneProduct ncbigene:27388
Pnpla2 GeneProduct ncbigene:66853
Pld1 GeneProduct ncbigene:18805
Dgkz GeneProduct ncbigene:104418
Ptdss1 GeneProduct ncbigene:19210
Pemt GeneProduct ncbigene:18618
Agpat4 GeneProduct ncbigene:68262
Cdipt GeneProduct ncbigene:52858
Chkb GeneProduct ncbigene:12651
Pcyt1a GeneProduct ncbigene:13026
Etnk1 GeneProduct ncbigene:75320
Agpat6 GeneProduct ncbigene:102247
Dgat2 GeneProduct ncbigene:67800
Pla2g1b GeneProduct ncbigene:18778
Pnpla3 Protein ncbigene:116939

References

  1. A mouse macrophage lipidome. Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, et al. J Biol Chem. 2010 Dec 17;285(51):39976–85. PubMed Europe PMC Scholia
  2. Glycerophosphate/Acylglycerophosphate acyltransferases. Yamashita A, Hayashi Y, Matsumoto N, Nemoto-Sasaki Y, Oka S, Tanikawa T, et al. Biology (Basel). 2014 Nov 19;3(4):801–30. PubMed Europe PMC Scholia