TCA cycle (WP434)
Mus musculus
The [[wikipedia:citric_acid_cycle|citric acid cycle]], also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle, (or rarely, the Szent-Gyorgyi-Krebs cycle) is a series of enzyme-catalysed chemical reactions of central importance in all living cells that use oxygen as part of cellular respiration. In eukaryotes, the citric acid cycle occurs in the matrix of the mitochondrion. The components and reactions of the citric acid cycle were established by seminal work from both [[wikipedia:Albert_Szent-Gyorgyi|Albert Szent-Gyorgyi]] and [[wikipedia:Hans_Krebs|Hans Krebs]]. [From [[wikipedia:Main_Page|Wikipedia]]]
Authors
Kdahlquist , Meredith Braymer , Adrien Defay , Martijn Van Iersel , Martina Summer-Kutmon , Daniela Digles , Egon Willighagen , and Eric WeitzActivity
Discuss this pathway
Check for ongoing discussions or start your own.
Cited In
- Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia (2020).
- Genomic footprints of dryland stress adaptation in Egyptian fat-tail sheep and their divergence from East African and western Asia cohorts (2017).
- Proteomic profiling of salivary gland after nonviral gene transfer mediated by conventional plasmids and minicircles (2014).
- Podocyte-specific KLF6 primes proximal tubule CaMK1D signaling to attenuate diabetic kidney disease (2024).
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Organisms
Mus musculusCommunities
Annotations
Pathway Ontology
citric acid cycle pathwayLabel | Type | Compact URI | Comment |
---|---|---|---|
Oxaloacetate | Metabolite | hmdb:HMDB0000223 | |
Malate | Metabolite | hmdb:HMDB0000156 | |
Isocitrate | Metabolite | hmdb:HMDB0000193 | |
Succinate | Metabolite | hmdb:HMDB0000254 | |
Pyruvate | Metabolite | hmdb:HMDB0000243 | |
Acetyl-CoA | Metabolite | hmdb:HMDB0001206 | |
Citrate | Metabolite | hmdb:HMDB0000094 | |
Fumarate | Metabolite | hmdb:HMDB0000134 | |
Succinyl-CoA | Metabolite | hmdb:HMDB0001022 | |
Pcx | GeneProduct | ncbigene:18563 | |
Pdha1 | GeneProduct | ncbigene:18597 | |
Pdhb | GeneProduct | ncbigene:68263 | |
Pdk4 | GeneProduct | ncbigene:27273 | |
Idh3b | GeneProduct | ncbigene:170718 | |
Pdhx | GeneProduct | ncbigene:27402 | |
Dlat | GeneProduct | ncbigene:235339 | |
Dld | GeneProduct | ncbigene:13382 | |
Sdha | GeneProduct | ncbigene:66945 | |
Mdh1 | GeneProduct | ncbigene:17449 | |
Suclg2 | GeneProduct | ncbigene:20917 | |
Aco2 | GeneProduct | ncbigene:11429 | |
Ppm2c | GeneProduct | ncbigene:381511 | |
Suclg1 | GeneProduct | ncbigene:56451 | |
Dlst | GeneProduct | ncbigene:78920 | |
Pdk2 | GeneProduct | ncbigene:18604 | |
Idh3g | GeneProduct | ncbigene:15929 | |
Sdhc | GeneProduct | ncbigene:66052 | |
Pdk1 | GeneProduct | ncbigene:228026 | |
Sdhd | GeneProduct | ncbigene:66925 | |
Sdhb | GeneProduct | ncbigene:67680 | |
Cs | GeneProduct | ncbigene:12974 | |
Sucla2 | GeneProduct | ncbigene:20916 | |
Idh3a | GeneProduct | ncbigene:67834 | |
Pdk3 | GeneProduct | ncbigene:236900 | |
Idh2 | GeneProduct | ncbigene:269951 | |
Ogdh | GeneProduct | ncbigene:18293 | |
Pdha2 | GeneProduct | ncbigene:18598 | |
4833426J09Rik | GeneProduct | ncbigene:382051 | |
Fh1 | GeneProduct | ncbigene:14194 | |
Mdh2 | GeneProduct | ncbigene:17448 |