Protein alkylation leading to liver fibrosis (WP3980)
Homo sapiens
Protein alkylation leading to liver fibrosis This pathway is based on descriptive text of the adverse outcome pathway (AOP) on https://aopwiki.org/aops/38
Authors
Marvin Martens and Egon WillighagenActivity
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Organisms
Homo sapiensCommunities
Adverse Outcome PathwaysAnnotations
Pathway Ontology
liver disease pathwayDisease Ontology
liver diseaseLabel | Type | Compact URI | Comment |
---|---|---|---|
thioacetamide | Metabolite | wikidata:Q416253 | |
Dimethylnitrosamine | Metabolite | chebi:35807 | |
allyl alcohol | Metabolite | chebi:16605 | |
retinol | Metabolite | chebi:50211 | |
CCl4 | Metabolite | chebi:27385 |
References
- Adverse outcome pathway development from protein alkylation to liver fibrosis. Horvat T, Landesmann B, Lostia A, Vinken M, Munn S, Whelan M. Arch Toxicol. 2017 Apr;91(4):1523–43. PubMed Europe PMC Scholia