Complement activation, classical pathway (WP200)
Mus musculus
For a description of pathway objects, see the WikiPathways Legend.
Authors
Nathan Salomonis , Kristina Hanspers , Martijn Van Iersel , Christine Chichester , Martina Summer-Kutmon , Eric Weitz , and Egon WillighagenActivity
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Cited In
- Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model (2020).
- Advanced Running Performance by Genetic Predisposition in Male Dummerstorf Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein (SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone (2016).
- Astrocyte secretome remodeling under iron deficiency: potential implications for brain iron homeostasis (2025).
- Deciphering age-related transcriptomic changes in the mouse retinal pigment epithelium.
- Whole Transcriptome RNA-Seq Reveals Drivers of Pathological Dysfunction in a Transgenic Model of Alzheimer's Disease (2025).
- GeneSetCart: assembling, augmenting, combining, visualizing, and analyzing gene sets (2025).
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Organisms
Mus musculusCommunities
Annotations
Pathway Ontology
classical complement pathwayLabel | Type | Compact URI | Comment |
---|---|---|---|
H₂O | Metabolite | hmdb:HMDB0002111 | |
C1s | GeneProduct | ncbigene:50908 | |
C1qb | GeneProduct | ncbigene:12260 | |
C1r | GeneProduct | ncbigene:50909 | |
C1qa | GeneProduct | ncbigene:12259 | update: C1QA HUMAN |
C1qc | GeneProduct | ncbigene:12262 | update C1QC HUMAN |
C8a | GeneProduct | ncbigene:230558 | |
Masp1 | GeneProduct | ncbigene:17174 | |
C2 | GeneProduct | ncbigene:12263 | |
C3 | GeneProduct | ncbigene:12266 | |
C9 | GeneProduct | ncbigene:12279 | |
C8b | GeneProduct | ncbigene:110382 | |
C6 | GeneProduct | ncbigene:12274 | |
C4b | GeneProduct | ncbigene:12268 | |
Daf1 | GeneProduct | ncbigene:13136 | |
C4a | GeneProduct | ensembl:ENSMUSG00000015451 | |
C7 | GeneProduct | ncbigene:109828 | |
Hc | GeneProduct | ncbigene:15139 |