Angiogenesis overview (WP1993)

Homo sapiens

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Overview of processes involved in the development of angiogenesis in humans.

For a description of pathway objects, see the WikiPathways Legend.

Authors

Helix , Susan Coort , Martijn Van Iersel , Egon Willighagen , and Lauren J. Dupuis

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

growth factor signaling pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
PIP2 Metabolite hmdb:HMDB0010032
ROBO1 GeneProduct ensembl:ENSG00000169855
PRKCA GeneProduct ensembl:ENSG00000154229
MAPK8 GeneProduct ensembl:ENSG00000107643
MMP2 GeneProduct ensembl:ENSG00000087245
GRB2 GeneProduct ensembl:ENSG00000177885
DAG1 GeneProduct ensembl:ENSG00000173402
CDC42 GeneProduct ensembl:ENSG00000070831
PDPK1 GeneProduct ensembl:ENSG00000140992
NRP1 GeneProduct ensembl:ENSG00000099250
AKT1 GeneProduct ensembl:ENSG00000142208
NCK1 GeneProduct ensembl:ENSG00000158092
MAPK14 GeneProduct ensembl:ENSG00000112062 p38 MAPK
CRK GeneProduct ensembl:ENSG00000167193
APC GeneProduct ensembl:ENSG00000134982
PTPN11 GeneProduct ensembl:ENSG00000179295
SOS1 GeneProduct ensembl:ENSG00000115904
MTOR GeneProduct ensembl:ENSG00000198793
PLCG1 GeneProduct ensembl:ENSG00000124181
PIK3CD GeneProduct ensembl:ENSG00000171608
PLC-gamma GeneProduct ensembl:ENSG00000124181
RAC1 GeneProduct ensembl:ENSG00000136238
IQGAP1 GeneProduct ensembl:ENSG00000140575
ROBO4 GeneProduct ensembl:ENSG00000154133
MAP2K1 GeneProduct ensembl:ENSG00000169032
RAF1 GeneProduct ensembl:ENSG00000132155
MMP9 GeneProduct ensembl:ENSG00000100985
PAK1 GeneProduct ncbigene:5058
ATF2 GeneProduct ensembl:ENSG00000115966
PLXND1 GeneProduct ensembl:ENSG00000004399
MMPs GeneProduct ensembl:ENSG00000087245
FRS2 GeneProduct ensembl:ENSG00000166225
PXN GeneProduct ensembl:ENSG00000089159
MAP2K6 GeneProduct ensembl:ENSG00000108984
MAP2K4 GeneProduct ensembl:ENSG00000065559
ELK1 GeneProduct ensembl:ENSG00000126767
MAP3K7 GeneProduct ensembl:ENSG00000135341
SRC GeneProduct ensembl:ENSG00000197122
VEGFA GeneProduct ensembl:ENSG00000112715
TEK GeneProduct ensembl:ENSG00000120156
MAPK11 GeneProduct ensembl:ENSG00000185386
SHC1 GeneProduct ensembl:ENSG00000160691
MAPK1 GeneProduct ensembl:ENSG00000100030
FGF1 GeneProduct ensembl:ENSG00000113578
SEMA4A GeneProduct ensembl:ENSG00000196189
VHL GeneProduct ensembl:ENSG00000134086
SEMA3A GeneProduct ensembl:ENSG00000075213
RAS GeneProduct ensembl:ENSG00000133703
TIMP4 GeneProduct ensembl:ENSG00000157150
SLIT2 GeneProduct ensembl:ENSG00000145147
ANGPT1 GeneProduct ensembl:ENSG00000154188
BAD GeneProduct ensembl:ENSG00000002330
TIMP2 GeneProduct ensembl:ENSG00000035862
DOK2 GeneProduct ensembl:ENSG00000147443
BMX GeneProduct ensembl:ENSG00000102010
SHB GeneProduct ensembl:ENSG00000107338
NOX4 GeneProduct ensembl:ENSG00000086991
PLA2G1B GeneProduct ensembl:ENSG00000170890
GRB14 GeneProduct ensembl:ENSG00000115290
KDR GeneProduct ensembl:ENSG00000128052
FGFR1 GeneProduct ensembl:ENSG00000077782
NOS3 GeneProduct ensembl:ENSG00000164867
MMP14 GeneProduct ensembl:ENSG00000157227
GRB7 GeneProduct ensembl:ENSG00000141738
Thrombin Protein omim:176930
WASP Protein uniprot:P42768
Dia1 Protein refseq:NP_031884.1
FAK Protein uniprot:Q14289
Ras None

References