EBV LMP1 signaling (WP1278)

Rattus norvegicus

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Authors

Christine Chichester and Egon Willighagen

Activity

last edited

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Cited In

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Organisms

Rattus norvegicus

Communities

Annotations

Pathway Ontology

Epstein-Barr virus infection pathway

Participants

Label Type Compact URI Comment
NP_001100528.1 GeneProduct ensembl:ENSRNOG00000008441
Nfkb2 GeneProduct ensembl:ENSRNOG00000019311
Mapk8 GeneProduct ensembl:ENSRNOG00000020155
Tnf GeneProduct ensembl:ENSRNOG00000000837
Rela GeneProduct ensembl:ENSRNOG00000030888
Pdlim7 GeneProduct ensembl:ENSRNOG00000013653
Tradd GeneProduct ensembl:ENSRNOG00000015179
Ifnb1 GeneProduct ensembl:ENSRNOG00000006268
Ikbkb GeneProduct ensembl:ENSRNOG00000019073
NP_001101224.1 GeneProduct ensembl:ENSRNOG00000004639
NP_001101058.1 GeneProduct ensembl:ENSRNOG00000022485
NP_001101390.1 GeneProduct ensembl:ENSRNOG00000005724
Nfkb1 GeneProduct ensembl:ENSRNOG00000023258
Irak1_predicted GeneProduct ensembl:ENSRNOG00000037263
Ccl5 GeneProduct ensembl:ENSRNOG00000010906
NP_001101771.1 GeneProduct ensembl:ENSRNOG00000003278
Chuk GeneProduct ncbigene:309361
Ikbkg GeneProduct ensembl:ENSRNOG00000037237
Ccl20 GeneProduct ensembl:ENSRNOG00000015992
Mapk1 GeneProduct ensembl:ENSRNOG00000001849
Hsp90aa1 GeneProduct ncbigene:299331

References

  1. TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB. Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, et al. J Biol Chem. 2006 Mar 24;281(12):7863–72. PubMed Europe PMC Scholia
  2. IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation. Song YJ, Jen KY, Soni V, Kieff E, Cahir-McFarland E. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2689–94. PubMed Europe PMC Scholia
  3. Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis. Lee JS, Lee JY, Son JW, Oh JH, Shin DM, Yuk JM, et al. Scand J Immunol. 2008 Jan;67(1):77–85. PubMed Europe PMC Scholia
  4. Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB. Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L, et al. J Leukoc Biol. 2008 Mar;83(3):648–62. PubMed Europe PMC Scholia