Non-homologous end joining (WP979)

Bos taurus

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(From http://en.wikipedia.org/wiki/Non-homologous_end_joining) Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA. NHEJ is referred to as "non-homologous" because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a homologous sequence to guide repair. NHEJ is evolutionarily conserved throughout all kingdoms of life and is the predominant double-strand break repair pathway in mammalian cells.

Authors

Martijn Van Iersel and Martina Summer-Kutmon

Activity

last edited

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Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

non-homologous end joining pathway of double-strand break repair

Participants

Label Type Compact URI Comment
PRKDC GeneProduct ensembl:ENSBTAG00000017019 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000253729
XRCC5 GeneProduct ensembl:ENSBTAG00000010426 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079246
XRCC6 GeneProduct ensembl:ENSBTAG00000006103 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000196419
XRCC4 GeneProduct ensembl:ENSBTAG00000024275 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000152422
NHEJ1 GeneProduct ensembl:ENSBTAG00000031041 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:79840
RAD50 GeneProduct ensembl:ENSBTAG00000011252 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000113522
MRE11A GeneProduct ensembl:ENSBTAG00000008925 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000020922
NHEJ1 GeneProduct ensembl:ENSBTAG00000031041 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000187736

References