Adipogenesis (WP869)

Pan troglodytes

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The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Authors

Kristina Hanspers , Martijn Van Iersel , and Martina Summer-Kutmon

Activity

last edited

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Cited In

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Organisms

Pan troglodytes

Communities

Annotations

Pathway Ontology

signaling pathway pertinent to development

Participants

Label Type Compact URI Comment
IGF1 GeneProduct ncbigene:741055
PTGIS GeneProduct ncbigene:458323
PPARD GeneProduct ncbigene:463188
CREB1 GeneProduct ncbigene:459901
MIXL1 GeneProduct ncbigene:737620
ID3 GeneProduct ncbigene:745532
WNT10B GeneProduct ncbigene:451870
STAT5A GeneProduct ncbigene:454681
STAT5B GeneProduct ncbigene:454679
NR3C1 GeneProduct ncbigene:471681
DDIT3 GeneProduct ncbigene:452017
LIF GeneProduct ncbigene:736309
CEBPB GeneProduct ncbigene:469969
LOC450614 GeneProduct ncbigene:450614
LOC738157 GeneProduct ncbigene:738157
RXRA GeneProduct ncbigene:464834
RARA GeneProduct ncbigene:454647
NR1H3 GeneProduct ncbigene:466507
LPL GeneProduct ncbigene:464031
SREBF1 GeneProduct ncbigene:454480
FAS GeneProduct ncbigene:738331
RBL1 GeneProduct ncbigene:735916
GATA3 GeneProduct ncbigene:450296
GATA2 GeneProduct ncbigene:460672
PPARG GeneProduct ncbigene:460178
MEF2A GeneProduct ncbigene:453680
MEF2B GeneProduct ncbigene:455871
MEF2C GeneProduct ncbigene:461760
MEF2D GeneProduct ncbigene:457396
ASIP GeneProduct ncbigene:747368
TNF GeneProduct ncbigene:744399
MIF GeneProduct ncbigene:748716
TGFB1 GeneProduct ncbigene:456060
SERPINE1 GeneProduct ncbigene:472467
SLC2A4 GeneProduct ncbigene:468443
SCD GeneProduct ncbigene:450676
TWIST1 GeneProduct ncbigene:450135
LEP GeneProduct ncbigene:449638
RETN GeneProduct ncbigene:742100
CFD GeneProduct ncbigene:455533
GTF3A GeneProduct ncbigene:467243
RB1 GeneProduct ncbigene:452715
RBL2 GeneProduct ncbigene:467978
ADIPOQ GeneProduct ncbigene:471032
ADFP GeneProduct ncbigene:465012
AGT GeneProduct ncbigene:450104
CDKN1A GeneProduct ncbigene:747442
SP1 GeneProduct ncbigene:451939
HMGA1 GeneProduct ncbigene:746594
PLIN GeneProduct ncbigene:467755
IL6 GeneProduct ncbigene:463288
GADD45A GeneProduct ncbigene:456929
GADD45B GeneProduct ncbigene:744311
CEBPD GeneProduct ncbigene:464163
BMP1 GeneProduct ncbigene:464042
BMP2 GeneProduct ncbigene:458090
BMP3 GeneProduct ncbigene:471189
BMP4 GeneProduct ncbigene:452912
NDN GeneProduct ncbigene:453273
FOXO1 GeneProduct ncbigene:467352
KLF5 GeneProduct ncbigene:452597
FOXC2 GeneProduct ncbigene:468058
NCOA1 GeneProduct ncbigene:459068
NCOA2 GeneProduct ncbigene:464226
PPARA GeneProduct ncbigene:458910
STAT3 GeneProduct ncbigene:454682
STAT2 GeneProduct ncbigene:451996
STAT1 GeneProduct ncbigene:459834
STAT6 GeneProduct ncbigene:452005
SOCS1 GeneProduct ncbigene:737070
SOCS3 GeneProduct ncbigene:454921
LIFR GeneProduct ncbigene:738797
IL6ST GeneProduct ncbigene:461866
MBNL1 GeneProduct ncbigene:460787
OSM GeneProduct ncbigene:736338
CTNNB1 GeneProduct ncbigene:450183
UCP1 GeneProduct ncbigene:461504
WNT5B GeneProduct ncbigene:467191
WNT1 GeneProduct ncbigene:742674
SMAD3 GeneProduct ncbigene:748161
FZD1 GeneProduct ncbigene:463524
DVL1 GeneProduct ncbigene:457191
HNF1A GeneProduct ncbigene:744121
RXRG GeneProduct ncbigene:457476
FRZB GeneProduct ncbigene:742552
INS GeneProduct ncbigene:449570
NAMPT GeneProduct ncbigene:463648
SPOCK1 GeneProduct ncbigene:462085
TRIB3 GeneProduct ncbigene:745623
GATA4 GeneProduct ncbigene:472698
NR2F1 GeneProduct ncbigene:461753
NRIP1 GeneProduct ncbigene:474071
RORA GeneProduct ncbigene:747433
PRLR GeneProduct ncbigene:461925
PNPLA3 GeneProduct ncbigene:458896
HIF1A GeneProduct ncbigene:746195
KLF6 GeneProduct ncbigene:450269
KLF7 GeneProduct ncbigene:459900
SFRP4 GeneProduct ncbigene:463356
NCOR1 GeneProduct ncbigene:741384
NCOR2 GeneProduct ncbigene:467150
EGR2 GeneProduct ncbigene:745846
EBF1 GeneProduct ncbigene:462229
EPAS1 GeneProduct ncbigene:459204
AHR GeneProduct ncbigene:463278
CISD1 GeneProduct ncbigene:450472
GDF10 GeneProduct ncbigene:735795
IRS1 GeneProduct ncbigene:459985
BSCL2 GeneProduct ncbigene:451262
LMNA GeneProduct ncbigene:457385
AGPAT2 GeneProduct ncbigene:748669
ZMPSTE24 GeneProduct ncbigene:456790
LPIN1 GeneProduct ncbigene:459036
LPIN2 GeneProduct ncbigene:455317
PCK1 GeneProduct ncbigene:458362
PCK2 GeneProduct ncbigene:452807
IRS2 GeneProduct ncbigene:452657
E2F4 GeneProduct ncbigene:454158

References

  1. Molecular regulation of adipogenesis. Rosen ED, Spiegelman BM. Annu Rev Cell Dev Biol. 2000;16:145–71. PubMed Europe PMC Scholia