G13 signaling pathway (WP826)

Gallus gallus

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The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: [[wikipedia:G12/G13_alpha_subunits|Wikipedia]]

Authors

Thomas Kelder , Christine Chichester , Martina Summer-Kutmon , and Eric Weitz

Activity

last edited

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Cited In

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Organisms

Gallus gallus

Communities

Annotations

Pathway Ontology

G protein mediated signaling pathway G protein mediated signaling pathway via Galpha12/Galpha13 family

Participants

Label Type Compact URI Comment
RTKN GeneProduct ensembl:ENSGALG00000043620 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6242
CFL2 GeneProduct ensembl:ENSGALG00000010027 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:1073
RHPN2 GeneProduct ensembl:ENSGALG00000004814 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:85415
RHOA GeneProduct ensembl:ENSGALG00000003806 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:387
CYFIP1 GeneProduct ensembl:ENSGALG00000016736 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:23191
GNA13 GeneProduct ensembl:ENSGALG00000036028 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10672
IQGAP2 GeneProduct ensembl:ENSGALG00000043276 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10788
IQGAP1 GeneProduct ensembl:ENSGALG00000030162 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8826
PIK3CD GeneProduct ensembl:ENSGALG00000002583 P42338
Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5293
ARHGDIB GeneProduct ensembl:ENSGALG00000011738 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:397
PIK3CB GeneProduct ensembl:ENSGALG00000005505 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5291
SH3RF1 GeneProduct ensembl:ENSGALG00000009692 Posh
Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:57630
LIMK1 GeneProduct ensembl:ENSGALG00000001076 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:3984
MYBPH GeneProduct ensembl:ENSGALG00000000164 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4608
cRac1A GeneProduct ensembl:ENSGALG00000007130 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5879
TNK2 GeneProduct ensembl:ENSGALG00000027983 S33596
Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:10188
PAK3 GeneProduct ensembl:ENSGALG00000008058 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5063
PIP4K2A GeneProduct ensembl:ENSGALG00000007877 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5305
MAPK10 GeneProduct ensembl:ENSGALG00000011109 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5602
CALM GeneProduct ensembl:ENSGALG00000026445 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:801
WASL GeneProduct ensembl:ENSGALG00000008797 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:8976
PIK3R2 GeneProduct ensembl:ENSGALG00000003428 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5296
PPP1CB GeneProduct ensembl:ENSGALG00000010026 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5500
MAP3K4 GeneProduct ensembl:ENSGALG00000020003 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4216
MYL1 GeneProduct ensembl:ENSGALG00000002907 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:4632
CIT GeneProduct ensembl:ENSGALG00000007354 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:11113
ARHGDIG GeneProduct ensembl:ENSGALG00000036819 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:398
ROCK1 GeneProduct ensembl:ENSGALG00000014922 S69211
Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6093
PIK3CA GeneProduct ensembl:ENSGALG00000008934 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:5290
CDC42 GeneProduct ensembl:ENSGALG00000004796 Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:998
RPS6KB1 GeneProduct ensembl:ENSGALG00000005198 A41687
Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:6198
ROCK2 GeneProduct ensembl:ENSGALG00000016451 BAA31594
Homology Mapping from Homo sapiens to Gallus gallus: Original ID = L:9475

References

  1. G protein pathways. Neves SR, Ram PT, Iyengar R. Science. 2002 May 31;296(5573):1636–9. PubMed Europe PMC Scholia