Blood clotting cascade

Andrew Kwa; WikiPathways Maintenance bot; Thomas Kelder; Christine Chichester; Eric Weitz

Blood clotting cascade (WP460)

Mus musculus

Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [[wikipedia:Coagulation|Wikipedia]]

Authors

Andrew Kwa , Thomas Kelder , Christine Chichester , and Eric Weitz

Activity

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Cited In

Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats (2016).

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Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

coagulation cascade pathway

Participants

Label	Type	Compact URI
F12	GeneProduct	ncbigene:58992
F11	GeneProduct	ncbigene:109821
F9	GeneProduct	ncbigene:14071
F10	GeneProduct	ncbigene:14058
Vwf	GeneProduct	ncbigene:22371
F5	GeneProduct	ncbigene:14067
F7	GeneProduct	ncbigene:14068
F2	GeneProduct	ncbigene:14061
F13b	GeneProduct	ncbigene:14060
Serpinf2	GeneProduct	ncbigene:18816
Plau	GeneProduct	ncbigene:18792
Plat	GeneProduct	ncbigene:18791
Serpinb2	GeneProduct	ncbigene:18788
Serpine1	GeneProduct	ncbigene:18787
Plg	GeneProduct	ncbigene:18815
Fgb	GeneProduct	ncbigene:110135
Fga	GeneProduct	ncbigene:14161
Fgg	GeneProduct	ncbigene:99571
F8	GeneProduct	ncbigene:14069
F8a	GeneProduct	ncbigene:14070

References

The current status of coagulation. Luchtman-Jones L, Broze GJ Jr. Ann Med. 1995 Feb;27(1):47–52. PubMed Europe PMC Scholia