Glucosinolate biosynthesis from methionine (WP4597)

Arabidopsis thaliana

Authors

Mikiko Takahashi , Atsushi Fukushima , Kristina Hanspers , Martina Summer-Kutmon , and Eric Weitz

Activity

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Organisms

Arabidopsis thaliana

Communities

Annotations

Pathway Ontology

classic metabolic pathway

References

1. Biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana: recombinant expression and characterization of methylthioalkylmalate synthase, the condensing enzyme of the chain-elongation cycle. Textor S, Bartram S, Kroymann J, Falk KL, Hick A, Pickett JA, et al. Planta. 2004 Apr;218(6):1026–35. PubMed Europe PMC Scholia
2. Desulfoglucosinolate sulfotransferases from Arabidopsis thaliana catalyze the final step in the biosynthesis of the glucosinolate core structure. Piotrowski M, Schemenewitz A, Lopukhina A, Müller A, Janowitz T, Weiler EW, et al. J Biol Chem. 2004 Dec 3;279(49):50717–25. PubMed Europe PMC Scholia
3. Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis. Grubb CD, Zipp BJ, Ludwig-Müller J, Masuno MN, Molinski TF, Abel S. Plant J. 2004 Dec;40(6):893–908. PubMed Europe PMC Scholia
4. The three desulfoglucosinolate sulfotransferase proteins in Arabidopsis have different substrate specificities and are differentially expressed. Klein M, Reichelt M, Gershenzon J, Papenbrock J. FEBS J. 2006 Jan;273(1):122–36. PubMed Europe PMC Scholia
5. MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis. Textor S, de Kraker JW, Hause B, Gershenzon J, Tokuhisa JG. Plant Physiol. 2007 May;144(1):60–71. PubMed Europe PMC Scholia
6. Kinetics and substrate specificities of desulfo-glucosinolate sulfotransferases in Arabidopsis thaliana. Klein M, Papenbrock J. Physiol Plant. 2009 Feb;135(2):140–9. PubMed Europe PMC Scholia
7. Arabidopsis thaliana encodes a bacterial-type heterodimeric isopropylmalate isomerase involved in both Leu biosynthesis and the Met chain elongation pathway of glucosinolate formation. Knill T, Reichelt M, Paetz C, Gershenzon J, Binder S. Plant Mol Biol. 2009 Oct;71(3):227–39. PubMed Europe PMC Scholia
8. Glucosinolate breakdown in Arabidopsis: mechanism, regulation and biological significance. Wittstock U, Burow M. Arabidopsis Book. 2010;8:e0134. PubMed Europe PMC Scholia