Circulating monocytes and cardiac macrophages in diastolic dysfunction (WP4474)

Mus musculus

Open in new tab
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
draft

Authors

Kristina Hanspers and Martina Summer-Kutmon

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Mus musculus

Communities

ExRNA

Annotations

Cell Type Ontology

monocyte myofibroblast cell intermediate monocyte macrophage monocyte macrophage myofibroblast cell

Pathway Ontology

disease pathway

Disease Ontology

hypertension hypertension cardiovascular system disease cardiovascular system disease

Participants

Label Type Compact URI Comment
ROS Metabolite chebi:26523
ROS Metabolite chebi:26523
ROS Metabolite chebi:26523
Ccl2 GeneProduct ensembl:ENSMUSG00000035385
Il10 GeneProduct ensembl:ENSMUSG00000016529
Spp1 GeneProduct ensembl:ENSMUSG00000029304
Il10 GeneProduct ensembl:ENSMUSG00000016529
Ccr2 GeneProduct ensembl:ENSMUSG00000049103

References

  1. Cardiac macrophages promote diastolic dysfunction. Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, et al. J Exp Med. 2018 Feb 5;215(2):423–40. PubMed Europe PMC Scholia