TCA cycle (Krebs cycle) (WP2624)
Arabidopsis thaliana
This pathway describes TCA cycle (Krebs Cycle) reactions in A. thaliana mitochondria.The metabolic links with the Glycolysis and Glutamate Biosynthesis are indicated. Protein identifiers for A. thaliana are from UNIPROT. The pathway is inspired from information drawn for Plant Physiology (Taiz and Zeiger) Third Edition and KEGG Pathways.
Authors
Anwesha Bohler , Sacha Bohler , Egon Willighagen , Martina Summer-Kutmon , and Eric WeitzActivity
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Organisms
Arabidopsis thalianaCommunities
Annotations
Pathway Ontology
citric acid cycle pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| CoA | Metabolite | kegg.compound:C00010 | |
| Succinyl-CoA | Metabolite | hmdb:HMDB0001022 | |
| citrate | Metabolite | kegg.compound:C00158 | |
| FAD+ | Metabolite | hmdb:HMDB0001248 | |
| succinate | Metabolite | kegg.compound:C00042 | |
| Acetyl-CoA | Metabolite | hmdb:HMDB0001206 | |
| fumarate | Metabolite | kegg.compound:C00122 | |
| FADH2 | Metabolite | hmdb:HMDB0001197 | |
| 2-oxoglutarate | Metabolite | kegg.compound:C00026 | |
| isocitrate | Metabolite | kegg.compound:C00311 | |
| oxaloacetate | Metabolite | kegg.compound:C00036 | |
| pyruvate | Metabolite | chebi:15361 | |
| CO2 | Metabolite | hmdb:HMDB0001967 | |
| NAD+ | Metabolite | hmdb:HMDB0000902 | |
| NADH | Metabolite | hmdb:HMDB0001487 | |
| H2O | Metabolite | hmdb:HMDB0002111 | |
| ATP | Metabolite | hmdb:HMDB0000538 | |
| ADP | Metabolite | kegg.compound:C00008 | |
| malate | Metabolite | kegg.compound:C00149 | |
| NADP+ | Metabolite | hmdb:HMDB0000902 | |
| NADPH | Metabolite | hmdb:HMDB0001487 | |
| isocitrate dehydrogenase 1 | Protein | uniprot:Q8LFC0 | |
| malic enzyme 2 | Protein | uniprot:Q8L7K9 | |
| malate dehydrogenase 2 | Protein | uniprot:Q9LKA3 | |
| pyruvate dehydrogenase alpha-1 | Protein | uniprot:P52901 | |
| succinyl-CoA synthetase alpha-1 | Protein | uniprot:P68209 | |
| fumarase | Protein | uniprot:P93033 | |
| 2-oxoglutarate dehydrogenase | Protein | uniprot:Q9FLH2 | |
| citrate synthase 5 | Protein | uniprot:Q9M1D3 | |
| succinate dehydrogenase FeS 1 | Protein | uniprot:Q8LBZ7 | |
| aconitase 2 | Protein | uniprot:Q9SIB9 | |
| isocitrate dehydrogenase | Protein | uniprot:Q9SRZ6 | |
| malic enzyme 1 | Protein | uniprot:Q9SIU0 | |
| pyruvate dehydrogenase alpha-2 | Protein | uniprot:Q8H1Y0 | |
| pyruvate dehydrogenase beta-1 | Protein | uniprot:Q38799 | |
| malate dehydrogenase 1 | Protein | uniprot:Q9ZP06 | |
| citrate synthase 4 | Protein | uniprot:P20115 | |
| aconitase 1 | Protein | uniprot:Q42560 | |
| aconitase 3 | Protein | uniprot:Q94A28 | |
| isocitrate dehydrogenase 2 | Protein | uniprot:P93032 | |
| isocitrate dehydrogenase 3 | Protein | uniprot:O81796 | |
| isocitrate dehydrogenase 4 | Protein | uniprot:Q9LQK9 | |
| isocitrate dehydrogenase 5 | Protein | uniprot:Q945K7 | |
| isocitrate dehydrogenase 6 | Protein | uniprot:Q8LG77 | |
| 2-oxoglutarate dehydrogenase | Protein | uniprot:F4IWV2 | |
| succinyl-CoA synthetase alpha-2 | Protein | uniprot:Q8LAD2 | |
| succinyl-CoA synthetase beta | Protein | uniprot:O82662 | |
| succinate dehydrogenase FeS 2 | Protein | uniprot:Q8LB02 | |
| succinate dehydrogenase FeS 3 | Protein | uniprot:Q9FJP9 | |
| succinate dehydrogenase 1 | Protein | uniprot:O82663 | |
| succinate dehydrogenase 2 | Protein | uniprot:Q9ZPX5 |