Splicing factor NOVA regulated synaptic proteins (WP1983)
Mus musculus
Synaptic Communication influenced by NOVA-splicing regulation
For a description of pathway objects, see the WikiPathways Legend.
Authors
Bahar Taneri , Martina Summer-Kutmon , Daniela Digles , and Egon WillighagenActivity
Discuss this pathway
Check for ongoing discussions or start your own.
Cited In
- Genomic footprints of dryland stress adaptation in Egyptian fat-tail sheep and their divergence from East African and western Asia cohorts (2017).
- Proteomic profiling of salivary gland after nonviral gene transfer mediated by conventional plasmids and minicircles (2014).
- An epigenome atlas of mouse adipocytes (2025).
- Mammary tissue microbiome analysis in PyMT mice reveals Methylobacteria as a commensal organism with potential therapeutic applications (2025).
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Organisms
Mus musculusCommunities
Annotations
Pathway Ontology
cadherin mediated signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| PIP2 | Metabolite | hmdb:HMDB0010032 | |
| Cav2.2 | GeneProduct | ensembl:ENSMUSG00000000058 | Validated target - predicted by splicing microarray |
| 4.1G | GeneProduct | ncbigene:13822 | Validated target - predicted by splicing microarray |
| NIK/Mapk4 | GeneProduct | ensembl:ENSMUSG00000024558 | Validated target - predicted by splicing microarray |
| N-Cadherin | GeneProduct | ncbigene:12558 | |
| SKIP | GeneProduct | ncbigene:66354 | Validated target - predicted by splicing microarray |
| Calsyntenin | GeneProduct | ncbigene:65945 | Validated target - predicted by splicing microarray |
| GIRK2 | GeneProduct | ncbigene:16522 | CLIP predicted target |
| Clasp1 | GeneProduct | ensembl:ENSMUSG00000064302 | Validated target - predicted by splicing microarray |
| Slo | GeneProduct | ncbigene:16531 | Validated target - predicted by splicing microarray |
| CASK | GeneProduct | ensembl:ENSMUSG00000031012 | Validated target - predicted by splicing microarray |
| neurochondrin | GeneProduct | ncbigene:26562 | Validated target - predicted by splicing microarray |
| GABAARg2 | GeneProduct | ncbigene:14406 | Validated target |
| JNK2 | GeneProduct | ncbigene:26420 | Validated target - predicted by CLIP |
| PMCA1 | GeneProduct | ncbigene:67972 | Validated target - predicted by splicing microarray |
| Plcb4 | GeneProduct | ensembl:ENSMUSG00000039943 | Validated target - predicted by splicing microarray |
| Rap1gap | GeneProduct | ncbigene:110351 | Validated target - predicted by splicing microarray |
| Syntaxin 2 | GeneProduct | ncbigene:13852 | Validated target - predicted by splicing microarray |
| Camk2g | GeneProduct | ensembl:ENSMUSG00000021820 | Validated target - predicted by splicing microarray |
| Igsf4a | GeneProduct | ncbigene:54725 | Validated target - predicted by splicing microarray |
| Neogenin | GeneProduct | ncbigene:18007 | Validated target - predicted by CLIP |
| Cask | GeneProduct | ensembl:ENSMUSG00000031012 | Validated target - predicted by splicing microarray |
| Gephrin | GeneProduct | ncbigene:268566 | Validated target - predicted by splicing microarray |
| Dab1 | GeneProduct | ensembl:ENSMUSG00000028519 | Validated target - predicted by bioinformatics |
| Aplp2 | GeneProduct | ensembl:ENSMUSG00000031996 | Validated target - predicted by splicing microarray |
| Kcnq2 | GeneProduct | ensembl:ENSMUSG00000016346 | Validated target - predicted by splicing microarray |
| Munc18 | GeneProduct | ncbigene:20911 | Validated target - predicted by splicing microarray |
| 4.1R | GeneProduct | ncbigene:269587 | Validated target - predicted by splicing microarray |
| 4.1B | GeneProduct | ncbigene:13823 | Validated target - predicted by splicing microarray |
| Chl1 | GeneProduct | ensembl:ENSMUSG00000030077 | Validated target - predicted by splicing microarray |
| Netrin G1 | GeneProduct | ncbigene:80883 | Validated target - predicted by splicing microarray |
| Rap1 | GeneProduct | ncbigene:57321 | |
| EphrinA5 | GeneProduct | ncbigene:13640 | Validated target - predicted by splicing microarray |
| NMDAR2B | GeneProduct | ncbigene:14812 | CLIP predicted target |
| NMDAR1 | GeneProduct | ncbigene:14810 | Validated target - predicted by splicing microarray |
| Ankyrin G | GeneProduct | ncbigene:11735 | Validated target - predicted by splicing microarray |
| GluR6 | GeneProduct | ncbigene:14806 | Validated target - predicted by splicing microarray |
| PKCz | GeneProduct | ncbigene:18762 | CLIP predicted target |
| GABAB2R | GeneProduct | ncbigene:242425 | CLIP predicted target |
| 4.1N | GeneProduct | ncbigene:13821 | Validated target - predicted by bioinformatics |
| Igsf4b | GeneProduct | ncbigene:94332 | Validated target - predicted by bioinformatics |
| MAP4 | Protein | uniprot:P27546 | Validated target - predicted by bioinformatics |
| AGRIN | Protein | uniprot:A2ASQ1 | Validated target - predicted by splicing microarray |
| CASK | Protein | uniprot:P06796 | Validated target - predicted by splicing microarray |
References
- Nova regulates brain-specific splicing to shape the synapse. Ule J, Ule A, Spencer J, Williams A, Hu JS, Cline M, et al. Nat Genet. 2005 Aug;37(8):844–52. PubMed Europe PMC Scholia
- An RNA map predicting Nova-dependent splicing regulation. Ule J, Stefani G, Mele A, Ruggiu M, Wang X, Taneri B, et al. Nature. 2006 Nov 30;444(7119):580–6. PubMed Europe PMC Scholia