G13 signaling pathway (WP1063)

Bos taurus

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: [[wikipedia:G12/G13_alpha_subunits|Wikipedia]]

Authors

Thomas Kelder , Christine Chichester , Martina Summer-Kutmon , and Eric Weitz

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

G protein mediated signaling pathway via Galpha12/Galpha13 family G protein mediated signaling pathway

Participants

Label Type Compact URI Comment
RTKN GeneProduct ensembl:ENSBTAG00000000490 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6242
PKN1 GeneProduct ensembl:ENSBTAG00000017037 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5585
CFL2 GeneProduct ensembl:ENSBTAG00000015053 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:1073
RHPN2 GeneProduct ensembl:ENSBTAG00000003089 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:85415
RHOA GeneProduct ensembl:ENSBTAG00000004279 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:387
PFN1 GeneProduct ensembl:ENSBTAG00000018312 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5216
ARHGEF1 GeneProduct ensembl:ENSBTAG00000018912 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:9138
CYFIP1 GeneProduct ensembl:ENSBTAG00000016894 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:23191
GNA13 GeneProduct ensembl:ENSBTAG00000046174 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10672
IQGAP2 GeneProduct ensembl:ENSBTAG00000000897 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10788
IQGAP1 GeneProduct ensembl:ENSBTAG00000013060 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:8826
PIK3CD GeneProduct ensembl:ENSBTAG00000018984 P42338
Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5293
ARHGDIB GeneProduct ensembl:ENSBTAG00000006039 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:397
PIK3CB GeneProduct ensembl:ENSBTAG00000006909 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5291
SH3RF1 GeneProduct ensembl:ENSBTAG00000001508 Posh
Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:57630
LIMK1 GeneProduct ensembl:ENSBTAG00000044083 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:3984
MYBPH GeneProduct ensembl:ENSBTAG00000011465 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4608
RAC1 GeneProduct ensembl:ENSBTAG00000009233 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5879
TNK2 GeneProduct ensembl:ENSBTAG00000021364 S33596
Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:10188
PAK3 GeneProduct ensembl:ENSBTAG00000015670 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5063
PIP4K2A GeneProduct ensembl:ENSBTAG00000018033 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5305
MAPK10 GeneProduct ensembl:ENSBTAG00000020048 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5602
WASL GeneProduct ensembl:ENSBTAG00000004643 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:8976
PIK3R2 GeneProduct ensembl:ENSBTAG00000002350 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5296
PPP1CB GeneProduct ensembl:ENSBTAG00000012447 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5500
WAS GeneProduct ensembl:ENSBTAG00000046555 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:7454
MAP3K4 GeneProduct ensembl:ENSBTAG00000020079 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4216
MYL1 GeneProduct ensembl:ENSBTAG00000009707 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:4632
CIT GeneProduct ensembl:ENSBTAG00000008963 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:11113
ARHGDIG GeneProduct ensembl:ENSBTAG00000027854 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:398
ROCK1 GeneProduct ensembl:ENSBTAG00000008403 S69211
Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6093
FCHSD1 GeneProduct ensembl:ENSBTAG00000030499 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:1729
PIK3CA GeneProduct ensembl:ENSBTAG00000009232 Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:5290
RPS6KB1 GeneProduct ensembl:ENSBTAG00000016851 A41687
Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:6198
ROCK2 GeneProduct ensembl:ENSBTAG00000005847 BAA31594
Homology Mapping from Homo sapiens to Bos taurus: Original ID = L:9475

References

  1. G protein pathways. Neves SR, Ram PT, Iyengar R. Science. 2002 May 31;296(5573):1636–9. PubMed Europe PMC Scholia