Synaptic vesicle pathway (WP3224)
Bos taurus
Pathway depicting synaptic transmission of neurotransmitters from the presynaptic nerve terminal to the synaptic cleft upon depolarization. Synaptotagmin mediated transport along the nerve cell cytoskeleton indicates the initial step of this process. Originally created by Joanna S. Fong and Nathan Salomonis in the Bruce Conklin laboratory 5/12/2000 for use in GenMAPP. Genes associated with neurotransmitter reuptake from the synaptic left were obtained from the Gene Ontology term GO:0001504. For additional information see: http://en.wikipedia.org/wiki/Synaptic_vesicle
Authors
Martina Summer-Kutmon and Eric WeitzActivity
Discuss this pathway
Check for ongoing discussions or start your own.
Cited In
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
synaptic vesicle cycle pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| L-Glutamine | Metabolite | hmdb:HMDB0000641 | |
| Dopamine | Metabolite | hmdb:HMDB0000073 | |
| Serotonin | Metabolite | hmdb:HMDB0000259 | |
| SYN1 | GeneProduct | ensembl:ENSBTAG00000005042 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000008056 |
| RAB3A | GeneProduct | ensembl:ENSBTAG00000010635 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105649 |
| SYN2 | GeneProduct | ensembl:ENSBTAG00000020260 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000157152 |
| SYN3 | GeneProduct | ensembl:ENSBTAG00000020636 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000185666 |
| SYT1 | GeneProduct | ensembl:ENSBTAG00000034693 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000067715 |
| VAMP2 | GeneProduct | ensembl:ENSBTAG00000003891 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000220205 |
| STX1B | GeneProduct | ensembl:ENSBTAG00000002349 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000099365 |
| STX2 | GeneProduct | ensembl:ENSBTAG00000007988 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000111450 |
| STX1A | GeneProduct | ensembl:ENSBTAG00000017075 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106089 |
| STX3 | GeneProduct | ensembl:ENSBTAG00000012820 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000166900 |
| SNAP25 | GeneProduct | ensembl:ENSBTAG00000008323 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000132639 |
| RIMS1 | GeneProduct | ensembl:ENSBTAG00000020238 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079841 |
| STXBP1 | GeneProduct | ensembl:ENSBTAG00000003525 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000136854 |
| UNC13C | GeneProduct | ensembl:ENSBTAG00000025522 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000137766 |
| UNC13B | GeneProduct | ensembl:ENSBTAG00000011397 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000198722 |
| UNC13A | GeneProduct | ensembl:ENSBTAG00000012682 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000130477 |
| CPLX3 | GeneProduct | ensembl:ENSBTAG00000021426 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000213578 |
| CPLX2 | GeneProduct | ensembl:ENSBTAG00000013741 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000145920 |
| NAPA | GeneProduct | ensembl:ENSBTAG00000013084 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105402 |
| NSF | GeneProduct | ensembl:ENSBTAG00000008442 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000073969 |
| CACNA1A | GeneProduct | ensembl:ENSBTAG00000014828 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000141837 |
| CACNA1B | GeneProduct | ensembl:ENSBTAG00000007882 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000148408 |
| SYP | GeneProduct | ensembl:ENSBTAG00000016096 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000102003 |
| DNM1 | GeneProduct | ensembl:ENSBTAG00000011307 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106976 |
| DNM1L | GeneProduct | ensembl:ENSBTAG00000011395 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000087470 |
| DNM2 | GeneProduct | ensembl:ENSBTAG00000013362 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079805 |
| DNM3 | GeneProduct | ensembl:ENSBTAG00000014319 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197959 |
| CLTA | GeneProduct | ensembl:ENSBTAG00000001137 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000122705 |
| CLTC | GeneProduct | ensembl:ENSBTAG00000016708 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000141367 |
| AP2S1 | GeneProduct | ensembl:ENSBTAG00000010584 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000042753 |
| AP2A1 | GeneProduct | ensembl:ENSBTAG00000019180 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000196961 |
| AP2A2 | GeneProduct | ensembl:ENSBTAG00000009915 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000183020 |
| AP2B1 | GeneProduct | ensembl:ENSBTAG00000020316 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000006125 |
| AP2M1 | GeneProduct | ensembl:ENSBTAG00000020106 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000161203 |
| SLC32A1 | GeneProduct | ensembl:ENSBTAG00000047894 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000101438 |
| SLC17A8 | GeneProduct | ensembl:ENSBTAG00000001088 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000179520 |
| SLC17A7 | GeneProduct | ensembl:ENSBTAG00000007036 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000104888 |
| SLC17A6 | GeneProduct | ensembl:ENSBTAG00000038347 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000091664 |
| SLC18A1 | GeneProduct | ensembl:ENSBTAG00000020788 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000036565 |
| SLC18A2 | GeneProduct | ensembl:ENSBTAG00000004739 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000165646 |
| SLC18A3 | GeneProduct | ensembl:ENSBTAG00000014990 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000187714 |
| SLC22A3 | GeneProduct | ensembl:ENSBTAG00000039080 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000146477 |
| SLC38A1 | GeneProduct | ensembl:ENSBTAG00000000859 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000111371 |
| PARK7 | GeneProduct | ensembl:ENSBTAG00000020518 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116288 |
| SLC1A3 | GeneProduct | ensembl:ENSBTAG00000018245 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079215 |
| CLN8 | GeneProduct | ensembl:ENSBTAG00000008584 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000182372 |
| SLC6A4 | GeneProduct | ensembl:ENSBTAG00000019349 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000108576 |
| SLC25A4 | GeneProduct | ensembl:ENSBTAG00000013208 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000151729 |
| ATP1A2 | GeneProduct | ensembl:ENSBTAG00000010551 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000018625 |