Type III interferon signaling (WP3173)

Bos taurus

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The recently identified type III interferon group consists of three IFN-λ (lambda) genes encoding molecules called IFN-λ1, IFN-λ2 and IFN-λ3 (also called IL29, IL28A and IL28B respectively). These IFNs signal through a receptor complex consisting of IL10R2 (also called CRF2-4) and IFNLR1 (also called CRF2-12).

Authors

Martina Summer-Kutmon

Activity

last edited

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Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

interleukin-28B signaling pathway Jak-Stat signaling pathway interleukin-29 signaling pathway interleukin-28A signaling pathway

Participants

Label Type Compact URI Comment
IFNL1 GeneProduct ensembl:ENSBTAG00000047691 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:282618
JAK1 GeneProduct ensembl:ENSBTAG00000003147 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3716
IL10RB GeneProduct ensembl:ENSBTAG00000019404 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3588
TYK2 GeneProduct ensembl:ENSBTAG00000011698 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7297
IFNLR1 GeneProduct ensembl:ENSBTAG00000001101 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:163702
STAT1 GeneProduct ensembl:ENSBTAG00000007867 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6772
STAT2 GeneProduct ensembl:ENSBTAG00000004380 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6773

References