Sulindac metabolic pathway (WP3150)

Bos taurus

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Authors

Martina Summer-Kutmon , Marianthi Kalafati , Mick Eikelhof , and Eric Weitz

Activity

last edited

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Cited In

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Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

classic metabolic pathway

Participants

Label Type Compact URI Comment
Sulindac-S Metabolite pubchem.compound:11245227
Sulfindac sulfide Metabolite chemspider:4509492
Sulindac-R Metabolite pubchem.compound:16046677
Sulindac sulfone Metabolite chemspider:4582441 The structure for the sulfone in the paper is inconsistent with the entries in ChemSpider and PubChem; I assume the paper made typographic errors.
MSRA GeneProduct ensembl:ENSBTAG00000021632 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000175806
MSRB2 GeneProduct ensembl:ENSBTAG00000044112 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000148450
CYP1B1 GeneProduct ensembl:ENSBTAG00000010531 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138061
MSRB3 GeneProduct ensembl:ENSBTAG00000044017 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000174099
CYP1A2 GeneProduct ensembl:ENSBTAG00000000085 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140505

References

  1. Studies on the metabolism and biological activity of the epimers of sulindac. Brunell D, Sagher D, Kesaraju S, Brot N, Weissbach H. Drug Metab Dispos. 2011 Jun;39(6):1014–21. PubMed Europe PMC Scholia