Iron metabolism in placenta (WP2908)
Bos taurus
During pregnancy, iron is transported from mother to fetus across the placenta. Iron is essential for many biological processes, including the transfer of oxygen in blood, but it can also be toxic. Elaborate and elegant mechanisms have evolved to make sure that the potential for oxidative damage is minimized. This description of Iron pathway through the placenta, and its regulation is purposed to understand the effect of Iron deficiency or Iron overload of the mother on the fetus.
Authors
Martina Summer-KutmonActivity
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Cited In
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Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
iron homeostasis pathway iron transport pathwayLabel | Type | Compact URI | Comment |
---|---|---|---|
FeIII | Metabolite | cas:20074-52-6 | |
FeII | Metabolite | cas:15438-31-0 | |
STEAP3 | GeneProduct | ensembl:ENSBTAG00000007111 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000115107 |
SLC40A1 | GeneProduct | ensembl:ENSBTAG00000010498 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138449 |
HEPHL1 | GeneProduct | ensembl:ENSBTAG00000022960 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000181333 |
ACO1 | GeneProduct | ensembl:ENSBTAG00000000555 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000122729 |
IREB2 | GeneProduct | ensembl:ENSBTAG00000002504 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000136381 |
SLC11A2 | GeneProduct | ensembl:ENSBTAG00000002355 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000110911 |
MCOLN1 | GeneProduct | ensembl:ENSBTAG00000005592 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000090674 |
TFR2 | GeneProduct | ensembl:ENSBTAG00000011738 | Transferrin receptorHomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106327 |
TF | Protein | ensembl:ENSBTAG00000007273 | TransferrinHomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000091513 |
TFRC | Protein | ensembl:ENSBTAG00000032719 | Transferrin receptorHomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000072274 |
HAMP | Protein | ensembl:ENSBTAG00000017042 | HAMPHomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105697 |
HAMP | Protein | ensembl:ENSBTAG00000017042 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105697 |
References
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