Eicosanoid Synthesis (Homo sapiens)

From WikiPathways

Jump to: navigation, search

Contents


Curation Tags

Description

In biochemistry, eicosanoids are signaling molecules made by oxidation of twenty-carbon essential fatty acids, (EFAs). They exert complex control over many bodily systems, mainly in inflammation or immunity, and as messengers in the central nervous system.

Source: Wikipedia


Bibliography

  1. Funk CD; ''Prostaglandins and leukotrienes: advances in eicosanoid biology.; ''Science, 2001 - PubMed

Categories

History

View all
CompareRevisionActionTimeUserComment
35467view12:07, 12 February 2010Thomasadded literature
35466view12:06, 12 February 2010ThomasModified description
34433view18:14, 10 December 2009MaintBotAutomatic update of empty xrefs
31982view13:11, 14 August 2009MaintBotFixed group labels
21031view11:30, 14 November 2008MaintBot[[Pathway:Homo sapiens:Eicosanoid Synthesis]] moved to [[Pathway:WP167]]: Moved to stable identifier
15401view22:56, 27 May 2008Khanspersconnectors and metabolites
15399view22:53, 27 May 2008KhanspersPeriodical save, work in progress
15397view22:43, 27 May 2008KhanspersPeriodical save, work in progress
13058view11:12, 17 May 2008MaintBotautomated metabolite conversion
8002view13:46, 7 January 2008MaintBot[[Pathway:Human:Eicosanoid Synthesis]] moved to [[Pathway:Homo sapiens:Eicosanoid Synthesis]]: Renaming species
7624view16:05, 18 December 2007MaintBotfixed category names
7337view12:42, 4 November 2007MaintBotAdded categories to GPML
6310view22:17, 22 May 2007A.Kwagpml file for [[Human:Eicosanoid_Synthesis]]

Pathway Info

DataNodes

View all 38 DataNodes

Name Type Backpage Header Database reference
Prostaglandin D2MetaboliteHMDB01403 (HMDB)
15-HETEMetabolite70608-72-9 (CAS)
PLA2G6GeneProductPLA2G6 | phospholipase A2 group VI (cytosolic...8398 (Entrez Gene)
PLA2G2AGeneProductPLA2G2A | phospholipase A2 group IIA (platelet...5320 (Entrez Gene)
ALOX5APGeneProductALOX5AP | arachidonate 5-lipoxygenase-activatin...241 (Entrez Gene)
5-HPETEMetaboliteHMDB01193 (HMDB)
ALOX5GeneProductALOX5 | arachidonate 5-lipoxygenase240 (Entrez Gene)
Leukotriene C4MetaboliteHMDB01198 (HMDB)
ALOX15GeneProductALOX15 | arachidonate 15-lipoxygenase246 (Entrez Gene)
PTGDSGeneProductPTGDS | prostaglandin D2 synthase 21kDa (brain)...5730 (Entrez Gene)
Peroxidase?GeneProduct (Other)
5-HETEMetabolite70608-72-9 (CAS)
DPEP1GeneProductDPEP1 | dipeptidase 1 (renal)1800 (Entrez Gene)
Thromboxane A2MetaboliteHMDB01452 (HMDB)
PTGISGeneProductPTGIS | prostaglandin I2 (prostacyclin) synthas...5740 (Entrez Gene)
Leukotriene A4MetaboliteHMDB01337 (HMDB)
ALOX12GeneProductALOX12 | arachidonate 12-lipoxygenase239 (Entrez Gene)
Leukotriene E4MetaboliteHMDB02200 (HMDB)
ALOX15BGeneProductALOX15B | arachidonate 15-lipoxygenase second ...247 (Entrez Gene)
PTGES2GeneProductPTGES2 | prostaglandin E synthase 280142 (Entrez Gene)
PTGS1GeneProductPTGS1 | prostaglandin-endoperoxide synthase 1 (...5742 (Entrez Gene)
PGD2 11-ketoreducGeneProduct (SwissProt)
PTGS2GeneProductPTGS2 | prostaglandin-endoperoxide synthase 2 (...5743 (Entrez Gene)
12-HETEMetabolite70608-72-9 (CAS)
TBXAS1GeneProductTBXAS1 | thromboxane A synthase 1 (platelet cy...6916 (Entrez Gene)
Arachidonic acidMetaboliteHMDB01043 (HMDB)
LTC4SGeneProductLTC4S | leukotriene C4 synthase4056 (Entrez Gene)
Thromboxane B2MetaboliteHMDB03252 (HMDB)
GGT1GeneProductGGT1 | gamma-glutamyltransferase 12678 (Entrez Gene)
Prostaglandin H2MetaboliteHMDB01381 (HMDB)
IPLA2(GAMMA)GeneProductIPLA2(GAMMA) | intracellular membrane-associate...50640 (Entrez Gene)
Prostaglandin F2aMetaboliteHMDB01139 (HMDB)
LTA4HGeneProductLTA4H | leukotriene A4 hydrolase4048 (Entrez Gene)
Leukotriene B4MetaboliteHMDB01085 (HMDB)
PGE2 9-ketoreducGeneProduct (SwissProt)
Leukotriene D4MetaboliteHMDB03080 (HMDB)
PTGESGeneProductPTGES | prostaglandin E synthase9536 (Entrez Gene)
Prostaglandin I2MetaboliteHMDB01335 (HMDB)
Retrieved from "http://wikipathways.org/index.php/Pathway:WP167"
Personal tools
Navigation