Energy Metabolism (Homo sapiens)

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Description

The PPARGC1A protein is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with the nuclear receptor PPARG, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. Source: Wikipedia (wikipedia:PPARGC1A)

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CompareRevisionActionTimeUserComment
45242view18:25, 7 October 2011AlexanderPicoOntology Term : 'energy metabolic pathway' added !
41103view23:22, 1 March 2011MaintBotRemoved redundant pathway information and comments
38811view08:31, 24 September 2010Jildaucompartment
38121view01:34, 13 August 2010AlexanderPicofixed legend
38118view01:00, 13 August 2010AlexanderPicoModified categories
38117view00:59, 13 August 2010AlexanderPicoModified description
38116view00:53, 13 August 2010AlexanderPicofinished connecting datanodes and lines
38115view00:23, 13 August 2010AlexanderPicoPeriodical save, work in progress
38094view00:29, 12 August 2010AlexanderPicofixed arrows and datanodes in top third of pathway
38093view23:58, 11 August 2010AlexanderPicoConnecting genes to database, fixing lines and datanodes
38091view23:49, 11 August 2010AlexanderPicoPeriodical save, work in progress
38089view23:38, 11 August 2010AlexanderPicoadded pathway name
38021view14:06, 30 July 2010MXFKoshoPeriodical save, work in progress
38020view13:59, 30 July 2010MXFKoshoSpecify description
37913view09:34, 16 July 2010MXFKoshoSpecify description
37910view02:35, 16 July 2010MXFKoshoSpecify description
37909view02:32, 16 July 2010MXFKoshoSpecify description
37908view02:26, 16 July 2010MXFKoshoPeriodical save, work in progress
37907view02:24, 16 July 2010MXFKosho
37906view02:16, 16 July 2010MXFKoshoPeriodical save, work in progress
37905view02:04, 16 July 2010MXFKoshoSpecify description
37904view01:59, 16 July 2010MXFKoshoSpecify description
37903view01:54, 16 July 2010MXFKoshoPeriodical save, work in progress
37902view01:45, 16 July 2010MXFKoshoSpecify description
37563view17:12, 11 June 2010MXFKoshoSpecify description
37559view13:51, 11 June 2010MXFKoshoSpecify description
37558view13:46, 11 June 2010MXFKoshoSpecify description
37557view13:38, 11 June 2010MXFKoshoPeriodical save, work in progress
37556view12:57, 11 June 2010MXFKoshoPeriodical save, work in progress
37290view21:21, 24 May 2010MXFKoshoSpecify description
37285view19:20, 24 May 2010MXFKoshoPeriodical save, work in progress
37284view19:01, 24 May 2010MXFKoshoSpecify description
37283view18:01, 24 May 2010MXFKoshoSpecify description
37282view15:01, 24 May 2010MXFKoshoPeriodical save, work in progress
37281view14:49, 24 May 2010MXFKoshoSpecify description
37280view10:44, 24 May 2010MXFKoshoSpecify description
37278view21:35, 23 May 2010MXFKoshoSpecify description
37268view19:36, 23 May 2010MXFKoshoSpecify description
37259view16:22, 23 May 2010MXFKoshoSpecify description
37258view16:09, 23 May 2010MXFKoshoPeriodical save, work in progress
37257view16:04, 23 May 2010MXFKoshoFinito
37256view15:59, 23 May 2010MXFKoshoPeriodical save, work in progress
37255view14:57, 23 May 2010MXFKoshoPeriodical save, work in progress
37254view14:47, 23 May 2010MXFKoshoPeriodical save, work in progress
37253view14:38, 23 May 2010MXFKoshoSpecify description
37252view14:21, 23 May 2010MXFKoshoSpecify description
37251view14:06, 23 May 2010MXFKoshoPeriodical save, work in progress
37250view12:51, 23 May 2010MXFKoshoPeriodical save, work in progress
37249view12:30, 23 May 2010MXFKoshoPeriodical save, work in progress
37247view11:38, 23 May 2010MXFKoshoPeriodical save, work in progress

External references

View all 51...

Name Type Database reference
MYBBP1AGeneProduct10514 (Entrez Gene)
CAMK4GeneProduct814 (Entrez Gene)
PRKAG2GeneProduct51422 (Entrez Gene)
SIRT1GeneProduct23411 (Entrez Gene)
PPP3CCGeneProduct5533 (Entrez Gene)
Unknown Transcription FactorsGeneProduct
RXRAGeneProduct6256 (Entrez Gene)
CREB1GeneProduct1385 (Entrez Gene)
MEF2DGeneProduct4209 (Entrez Gene)
GABPAGeneProduct2551 (Entrez Gene)
PRKAA2GeneProduct5563 (Entrez Gene)
PPARGC1AGeneProduct10891 (Entrez Gene)
GSK3BGeneProduct2932 (Entrez Gene)
TFB1MGeneProduct51106 (Entrez Gene)
TFAMGeneProduct7019 (Entrez Gene)
TFB2MGeneProduct64216 (Entrez Gene)
MEF2BGeneProduct100271849 (Entrez Gene)
PPARAGeneProduct5465 (Entrez Gene)
PPP3CAGeneProduct5530 (Entrez Gene)
UCP2GeneProduct7351 (Entrez Gene)
PPP3R2GeneProduct5535 (Entrez Gene)
PPARGC1BGeneProduct133522 (Entrez Gene)
PRKAB2GeneProduct5565 (Entrez Gene)
CAMK2GGeneProduct818 (Entrez Gene)
PPARDGeneProduct5467 (Entrez Gene)
NCOA1GeneProduct8648 (Entrez Gene)
PPARGGeneProduct5468 (Entrez Gene)
MED1GeneProduct5469 (Entrez Gene)
NRF1GeneProduct4899 (Entrez Gene)
FOXO3GeneProduct2309 (Entrez Gene)
MAPK14GeneProduct1432 (Entrez Gene)
UCP3GeneProduct7352 (Entrez Gene)
MEF2AGeneProduct4205 (Entrez Gene)
Unknown Transcription Factors GeneProduct
MEF2CGeneProduct4208 (Entrez Gene)
EP300GeneProduct2033 (Entrez Gene)
HDAC1GeneProduct3065 (Entrez Gene)
SIRT3GeneProduct23410 (Entrez Gene)
PPP3CBGeneProduct5532 (Entrez Gene)
CAMK4GeneProduct
PPP3R1GeneProduct5534 (Entrez Gene)
FOXO1GeneProduct2308 (Entrez Gene)
PRKAA1GeneProduct5562 (Entrez Gene)
ATF2GeneProduct1386 (Entrez Gene)
PRKAB1GeneProduct5564 (Entrez Gene)
PRMT1GeneProduct3276 (Entrez Gene)
PRKAG1GeneProduct5571 (Entrez Gene)
PPRC1GeneProduct23082 (Entrez Gene)
PRKAG3GeneProduct53632 (Entrez Gene)
ESRRAGeneProduct2101 (Entrez Gene)
AcetylMetabolite
Retrieved from "http://wikipathways.org/index.php/Pathway:WP1541"
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