BMP signalling and regulation (Homo sapiens)
"BMP signals are mediated by type I and II BMP receptors and their downstream molecules Smad1, 5 and 8. Phosphorylated Smad1, 5 and 8 proteins form a complex with Smad4 and then are translocated into the nucleus where they interact with other transcription factors, such as Runx2 in osteoblasts." (Chen 2004)
- Chen D, Zhao M, Mundy GR; ''Bone morphogenetic proteins.; ''Growth Factors, 2004 - PubMed
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|BMPR2||GeneProduct||659 (Entrez Gene)|