Phase I, non P450 (Homo sapiens)

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Contents



Curation Tags

Description

This pathway lists several phase 1 biotransformations and their related enzymes.

Ontology Tags

 

Bibliography

  1. Klaassen, C.D., Watkins III, J.B.; ''Casarett & Doull's Essentials of Toxicology; '', 2003

Categories


History

View all
CompareRevisionActionTimeUserComment
61693view22:57, 16 April 2013MaintBotModified description
59200view19:14, 22 February 2013MaintBotUpdated Ensembl and UniProt data source
56211view17:55, 4 January 2013EveloOntology Term : 'PW:0000375' removed !
56210view17:55, 4 January 2013EveloOntology Term : 'cytochrome P450-independent phase I biotransformation pathway' added !
45252view18:38, 7 October 2011KhanspersOntology Term : 'phase I biotransformation pathway via cytochrome P450' added !
41188view23:43, 1 March 2011MaintBotRemoved redundant pathway information and comments
31942view12:58, 14 August 2009MaintBotFixed group labels
29886view11:13, 9 June 2009Thomasupdated ensembl references
20967view11:30, 14 November 2008MaintBot[[Pathway:Homo sapiens:Phase I - non P450 biotransformations]] moved to [[Pathway:WP136]]: Moved to stable identifier
14590view06:31, 23 May 2008Thomasadded metabolite boxes + links
11463view11:12, 1 April 2008ThomasModified categories
11073view14:31, 11 March 2008Thomas[[Pathway:Homo sapiens:Phase I, non P450 biotransformations]] moved to [[Pathway:Homo sapiens:Phase I - non P450 biotransformations]]: invalid character
11034view10:20, 4 March 2008Evelo[[Pathway:Homo sapiens:Phase I biotransformations]] moved to [[Pathway:Homo sapiens:Phase I, non P450 biotransformations]]: We also have a P450 pathway, which belongs to Phase 1
11033view10:20, 4 March 2008Evelorenamed
11019view12:14, 3 March 2008Thomasadded bibliography
11018view12:12, 3 March 2008ThomasModified description
11014view12:10, 3 March 2008Thomasadded gene annotations, translated labels
11011view11:52, 3 March 2008Thomas[[Pathway:Homo sapiens:Phase I]] moved to [[Pathway:Homo sapiens:Phase I biotransformations]]
10971view11:26, 28 February 2008RollieCreated PhaseI pathway

External references

View all 12...

Name Type Database reference
PON2GeneProductENSG00000105854 (Ensembl)
thio estersMetabolite
ESDGeneProductENSG00000139684 (Ensembl)
amidesMetabolite32988 (ChEBI)
CES7GeneProductENSG00000159398 (Ensembl)
CES1GeneProductENSG00000196959 (Ensembl)
CES2GeneProductENSG00000172831 (Ensembl)
PON3GeneProductENSG00000105852 (Ensembl)
LIPAGeneProductENSG00000107798 (Ensembl)
carboxylic acid estersMetabolite
PON1GeneProductENSG00000005421 (Ensembl)
Phosphoric acid estersMetabolite
Retrieved from "http://wikipathways.org/index.php/Pathway:WP136"
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