Estrogen signaling pathway (Homo sapiens)
Estrogen receptor refers to a group of receptors which are activated by the hormone 17Î²-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. The main function of the estrogen receptor is as a DNA binding transcription factor which regulates gene expression. However the estrogen receptor also has additional functions independent of DNA binding.
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|C-FOS||GeneProduct||2353 (Entrez Gene)|
|MAPKKK||GeneProduct||673 (Entrez Gene)|
|SP1||GeneProduct||6667 (Entrez Gene)|
|Cyclic AMP||Metabolite||6076 (PubChem)|
|ERE||GeneProduct||2099 (Entrez Gene)|