Type I Interferon Signaling Pathways. Both classical and non-canonical signaling is shown.
Comments
Type your comment here
Ontology Tags
Saving...
No Tags!
Bibliography
View all 29 references
Darnell JE Jr; ''STATs and gene regulation.; ''Science, 1997 - PubMed
Uddin S, Sher DA, Alsayed Y, Pons S, Colamonici OR, Fish EN, White MF, Platanias LC; ''Interaction of p59fyn with interferon-activated Jak kinases.; ''Biochem Biophys Res Commun, 1997 - PubMed
Burfoot MS, Rogers NC, Watling D, Smith JM, Pons S, Paonessaw G, Pellegrini S, White MF, Kerr IM; ''Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons.; ''J Biol Chem, 1997 - PubMed
Ahmad S, Alsayed YM, Druker BJ, Platanias LC; ''The type I interferon receptor mediates tyrosine phosphorylation of the CrkL adaptor protein.; ''J Biol Chem, 1997 - PubMed
Gutch MJ, Daly C, Reich NC; ''Tyrosine phosphorylation is required for activation of an alpha interferon-stimulated transcription factor.; ''Proc Natl Acad Sci U S A, 1992 - PubMed
Uddin S, Fish EN, Sher D, Gardziola C, Colamonici OR, Kellum M, Pitha PM, White MF, Platanias LC; ''The IRS-pathway operates distinctively from the Stat-pathway in hematopoietic cells and transduces common and distinct signals during engagement of the insulin or interferon-alpha receptors.; ''Blood, 1997 - PubMed
Farrar JD, Smith JD, Murphy TL, Murphy KM; ''Recruitment of Stat4 to the human interferon-alpha/beta receptor requires activated Stat2.; ''J Biol Chem, 2000 - PubMed
Owczarek CM, Hwang SY, Holland KA, Gulluyan LM, Tavaria M, Weaver B, Reich NC, Kola I, Hertzog PJ; ''Cloning and characterization of soluble and transmembrane isoforms of a novel component of the murine type I interferon receptor, IFNAR 2.; ''J Biol Chem, 1997 - PubMed
Beadling C, Guschin D, Witthuhn BA, Ziemiecki A, Ihle JN, Kerr IM, Cantrell DA; ''Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.; ''EMBO J, 1994 - PubMed
Yan H, Krishnan K, Lim JT, Contillo LG, Krolewski JJ; ''Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction.; ''Mol Cell Biol, 1996 - PubMed
You M, Yu DH, Feng GS; ''Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway.; ''Mol Cell Biol, 1999 - PubMed
Domanski P, Witte M, Kellum M, Rubinstein M, Hackett R, Pitha P, Colamonici OR; ''Cloning and expression of a long form of the beta subunit of the interferon alpha beta receptor that is required for signaling.; ''J Biol Chem, 1995 - PubMed
Novick D, Cohen B, Rubinstein M; ''Soluble interferon-alpha receptor molecules are present in body fluids.; ''FEBS Lett, 1992 - PubMed
Müller M, Briscoe J, Laxton C, Guschin D, Ziemiecki A, Silvennoinen O, Harpur AG, Barbieri G, Witthuhn BA, Schindler C; ''The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction.; ''Nature, 1993 - PubMed
David M, Chen HE, Goelz S, Larner AC, Neel BG; ''Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1.; ''Mol Cell Biol, 1995 - PubMed
Fish EN, Uddin S, Korkmaz M, Majchrzak B, Druker BJ, Platanias LC; ''Activation of a CrkL-stat5 signaling complex by type I interferons.; ''J Biol Chem, 1999 - PubMed
Schindler C, Shuai K, Prezioso VR, Darnell JE Jr; ''Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor.; ''Science, 1992 - PubMed
Uddin S, Yenush L, Sun XJ, Sweet ME, White MF, Platanias LC; ''Interferon-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinase.; ''J Biol Chem, 1995 - PubMed
Liu B, Liao J, Rao X, Kushner SA, Chung CD, Chang DD, Shuai K; ''Inhibition of Stat1-mediated gene activation by PIAS1.; ''Proc Natl Acad Sci U S A, 1998 - PubMed
Uddin S, Gardziola C, Dangat A, Yi T, Platanias LC; ''Interaction of the c-cbl proto-oncogene product with the Tyk-2 protein tyrosine kinase.; ''Biochem Biophys Res Commun, 1996 - PubMed
Fu XY; ''A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein tyrosine kinase(s).; ''Cell, 1992 - PubMed
Uzé G, Lutfalla G, Gresser I; ''Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA.; ''Cell, 1990 - PubMed
Novick D, Cohen B, Rubinstein M; ''The human interferon alpha/beta receptor: characterization and molecular cloning.; ''Cell, 1994 - PubMed
Platanias LC, Uddin S, Bruno E, Korkmaz M, Ahmad S, Alsayed Y, Van Den Berg D, Druker BJ, Wickrema A, Hoffman R; ''CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors.; ''Exp Hematol, 1999 - PubMed
Song MM, Shuai K; ''The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities.; ''J Biol Chem, 1998 - PubMed
Colamonici OR, Domanski P; ''Identification of a novel subunit of the type I interferon receptor localized to human chromosome 21.; ''J Biol Chem, 1993 - PubMed
Baychelier F, Nardeux PC, Cajean-Feroldi C, Ermonval M, Guymarho J, Tovey MG, Eid P; ''Involvement of the Gab2 scaffolding adapter in type I interferon signalling.; ''Cell Signal, 2007 - PubMed
Platanias LC, Uddin S, Yetter A, Sun XJ, White MF; ''The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2.; ''J Biol Chem, 1996 - PubMed
Uddin S, Majchrzak B, Woodson J, Arunkumar P, Alsayed Y, Pine R, Young PR, Fish EN, Platanias LC; ''Activation of the p38 mitogen-activated protein kinase by type I interferons.; ''J Biol Chem, 1999 - PubMed
Ontology Tags
Bibliography
Categories
History
External references