Statin Pathway (Homo sapiens)

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Contents 1 Curation Tags 2 Description 3 Ontology Tags 4 Bibliography 5 Categories 6 History 7 External references

Curation Tags

Description

Ontology Tags

Bibliography

1. Chen H, Ikeda U, Shimpo M, Shimada K; ''Direct effects of statins on cells primarily involved in atherosclerosis.; ''Hypertens Res, 2000 - PubMed

Categories

History

View all

Compare	Revision	Action	Time	User	Comment
	59209	view	19:50, 22 February 2013	MaintBot	Updated Ensembl and UniProt data source
	45117	view	23:22, 6 October 2011	Khanspers	Ontology Term : 'hepatocyte' added !
	45116	view	23:20, 6 October 2011	Khanspers	Ontology Term : 'statin drug pathway' added !
	45115	view	23:20, 6 October 2011	Khanspers	Ontology Term : 'CL:0000679' removed !
	43561	view	21:13, 29 June 2011	Samuel Sklar	mir33 added
	41203	view	23:44, 1 March 2011	MaintBot	Removed redundant pathway information and comments
	40175	view	21:38, 14 February 2011	AlexanderPico	added legend
	40174	view	21:34, 14 February 2011	AlexanderPico	Modified description
	39393	view	02:43, 20 November 2010	AlexanderPico	Specify description
	39392	view	02:35, 20 November 2010	AlexanderPico	updated cells
	38114	view	23:59, 12 August 2010	AlexanderPico
	38074	view	04:30, 9 August 2010	AlexanderPico	liver cell
	38073	view	04:26, 9 August 2010	AlexanderPico
	38072	view	04:25, 9 August 2010	AlexanderPico	overhaul
	37434	view	23:17, 2 June 2010	Nsalomonis	Specify description
	35535	view	14:14, 12 February 2010	Thomas	added literature
	34460	view	18:26, 10 December 2009	MaintBot	Automatic update of empty xrefs
	34038	view	18:56, 9 December 2009	Khanspers	Periodical save, work in progress
	34024	view	18:46, 9 December 2009	Khanspers	Periodical save, work in progress
	33994	view	18:36, 9 December 2009	Khanspers	Periodical save, work in progress
	32094	view	13:43, 14 August 2009	MaintBot	Fixed group labels
	29996	view	22:27, 23 June 2009	Nsalomonis	Modified description
	21586	view	11:32, 14 November 2008	MaintBot	[[Pathway:Homo sapiens:Statin Pathway PharmGKB]] moved to [[Pathway:WP430]]: Moved to stable identifier
	20390	view	19:54, 3 November 2008	AlexanderPico
	18816	view	08:31, 7 September 2008	AlexanderPico	Modified categories
	16871	view	17:42, 27 June 2008	Nsalomonis	reduced legend
	16869	view	17:40, 27 June 2008	Nsalomonis	layout
	16867	view	17:37, 27 June 2008	Nsalomonis	change
	16865	view	17:30, 27 June 2008	Nsalomonis	more
	16863	view	17:23, 27 June 2008	Nsalomonis	compacted
	16861	view	17:19, 27 June 2008	Nsalomonis	Reverted to version '01:43, 18 June 2008' by Nsalomonis
	16858	view	17:19, 27 June 2008	Nsalomonis	Reverted to version '01:42, 18 June 2008' by Nsalomonis
	16582	view	19:22, 22 June 2008	AlexanderPico	Modified categories
	16321	view	01:43, 18 June 2008	Nsalomonis	Specify description
	16319	view	01:42, 18 June 2008	Nsalomonis	Specify description
	16317	view	01:39, 18 June 2008	Nsalomonis	updated URL for GenMAPP notes
	15281	view	07:25, 27 May 2008	Thomas	grouped APO
	15016	view	01:10, 25 May 2008	AlexanderPico	Connected!
	15014	view	01:01, 25 May 2008	AlexanderPico	Fixed metabolites
	15012	view	00:54, 25 May 2008	AlexanderPico	Periodical save, work in progress
	13119	view	11:17, 17 May 2008	MaintBot	automated metabolite conversion
	11881	view	18:17, 8 May 2008	Khanspers	Changed author and contact info
	8402	view	13:46, 7 January 2008	MaintBot	[[Pathway:Human:Statin Pathway PharmGKB]] moved to [[Pathway:Homo sapiens:Statin Pathway PharmGKB]]: Renaming species
	7818	view	16:20, 18 December 2007	MaintBot	fixed category names
	7395	view	12:42, 4 November 2007	MaintBot	Added categories to GPML
	7190	view	12:31, 4 November 2007	MaintBot	Added description to GPML
	7135	view	19:24, 16 October 2007	AlexanderPico	test
	6929	view	21:24, 24 July 2007	Nsalomonis	Added legend for pathway
	19543	view	22:18, 22 May 2007	BruceConklin	gpml file for [[Human:Statin_Pathway_PharmGKB]]
	6392	view	22:18, 22 May 2007	Nsalomonis	gpml file for [[Human:Statin_Pathway_PharmGKB]]

External references

View all 32...

Name	Type	Database reference
VLDL	Metabolite	C01834 (Kegg Compound)
Acetyl-CoA	Metabolite	HMDB01206 (HMDB)
CYP7A1	GeneProduct	1581 (Entrez Gene)
TRNP	GeneProduct	4571 (Entrez Gene)
SOAT1	GeneProduct	6646 (Entrez Gene)
Phospholipid	Metabolite	C00865 (Kegg Compound)
DGAT1	GeneProduct	8694 (Entrez Gene)
APOC2	GeneProduct	344 (Entrez Gene)
LDLR	GeneProduct	3949 (Entrez Gene)
Cholesterol	Unknown	57-88-5 (CAS)
SCARB1	GeneProduct	949 (Entrez Gene)
Cholesterol ester	Metabolite	C02530 (Kegg Compound)
LRP1	GeneProduct	4035 (Entrez Gene)
LDL	Metabolite	C01834 (Kegg Compound)
LPL	GeneProduct	4023 (Entrez Gene)
HMGCR	GeneProduct	3156 (Entrez Gene)
LIPC	GeneProduct	3990 (Entrez Gene)
APOC3	GeneProduct	345 (Entrez Gene)
CETP	GeneProduct	1071 (Entrez Gene)
PLTP	GeneProduct	5360 (Entrez Gene)
LCAT	GeneProduct	3931 (Entrez Gene)
Cholic Acid	Unknown	81-25-4 (CAS)
ABCA1	GeneProduct	19 (Entrez Gene)
Statin	Metabolite
APOA1	GeneProduct	335 (Entrez Gene)
Fatty acid	Metabolite	C00162 (Kegg Compound)
APOA4	GeneProduct	337 (Entrez Gene)
Triglyceride	Metabolite	C00422 (Kegg Compound)
APOC1	GeneProduct	341 (Entrez Gene)
IDL	Metabolite	C01834 (Kegg Compound)
APOE	GeneProduct	348 (Entrez Gene)
HDL	Metabolite	C01834 (Kegg Compound)