Myometrial Relaxation and Contraction Pathways (Mus musculus)

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Curation Tags

Description

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Comments

GenMAPP notes 
References: (1) Up-regulation of nitric oxide synthase and modulation of the guanylate cyclase activity by corticotropin-releasing hormone but not urocortin II or urocortin III in cultured human pregnant myometrial cells.

Aggelidou E, Hillhouse EW, Grammatopoulos DK. PMID: 11854458 (2) Is up-regulation of phosphodiesterase 4 activity by PGE2 involved in the desensitization of beta-mimetics in late pregnancy human myometrium?

Mehats C, Tanguy G, Dallot E, Cabrol D, Ferre F, Leroy MJ. PMID: 11701706

GenMAPP remarks 
Right-click here to see references
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP289(r21289) with a 90% conversion rate.

Ontology Tags

 

Bibliography

  1. Méhats C, Tanguy G, Dallot E, Cabrol D, Ferré F, Leroy MJ; ''Is up-regulation of phosphodiesterase 4 activity by PGE2 involved in the desensitization of beta-mimetics in late pregnancy human myometrium?; ''J Clin Endocrinol Metab, 2001 - PubMed
  2. Aggelidou E, Hillhouse EW, Grammatopoulos DK; ''Up-regulation of nitric oxide synthase and modulation of the guanylate cyclase activity by corticotropin-releasing hormone but not urocortin II or urocortin III in cultured human pregnant myometrial cells.; ''Proc Natl Acad Sci U S A, 2002 - PubMed

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History

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CompareRevisionActionTimeUserComment
47969view13:36, 23 April 2012MartijnVanIerseladded cell
47968view13:34, 23 April 2012MartijnVanIersellayout, added nucleus
47772view05:36, 6 April 2012Khanspersupdated xref
41284view00:22, 2 March 2011MaintBotRemoved redundant pathway information and comments
35258view20:16, 11 February 2010Thomasmoved references from comment to bibliography
34385view22:49, 9 December 2009MaintBotAutomatic update of empty xrefs
32693view23:21, 31 August 2009KhanspersAdded ATP xref
32692view23:20, 31 August 2009Khanspersadded xrefs
32417view17:07, 15 August 2009MaintBotFixed text labels
32074view13:37, 14 August 2009MaintBotFixed group labels
31445view21:08, 13 August 2009MaintBotFixed text labels
30819view23:57, 29 July 2009MaintBotConverted from Homo sapiens
21488view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:Smooth muscle contraction]] moved to [[Pathway:WP385]]: Moved to stable identifier
8398view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Smooth muscle contraction]] moved to [[Pathway:Mus musculus:Smooth muscle contraction]]: Renaming species
7816view16:19, 18 December 2007MaintBotfixed category names
7489view12:42, 4 November 2007MaintBotAdded categories to GPML
6495view22:19, 22 May 2007Nsalomonisgpml file for [[Mouse:Smooth_muscle_contraction]]

External references

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Name Type Database reference
Atf6bGeneProduct12915 (Entrez Gene)
Adcy2GeneProduct210044 (Entrez Gene)
Grk6GeneProduct26385 (Entrez Gene)
PrkcaGeneProduct18750 (Entrez Gene)
Cyclic AMPMetaboliteHMDB00058 (HMDB)
PrkcbGeneProduct18751 (Entrez Gene)
Atf2GeneProduct11909 (Entrez Gene)
Gstt2GeneProduct14872 (Entrez Gene)
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GNG5GeneProduct
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Prkar1bGeneProduct19085 (Entrez Gene)
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Nfkb1GeneProduct18033 (Entrez Gene)
Myl2GeneProduct17906 (Entrez Gene)
Ets2GeneProduct23872 (Entrez Gene)
Guca2aGeneProduct14915 (Entrez Gene)
Igfbp1GeneProduct16006 (Entrez Gene)
GUCY2EGeneProduct
Igfbp2GeneProduct16008 (Entrez Gene)
Grk5GeneProduct14773 (Entrez Gene)
Igfbp4GeneProduct16010 (Entrez Gene)
Gnb1GeneProduct14688 (Entrez Gene)
AdmGeneProduct11535 (Entrez Gene)
Gnb3GeneProduct14695 (Entrez Gene)
OxtrGeneProduct18430 (Entrez Gene)
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Igfbp6GeneProduct16012 (Entrez Gene)
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Nos1GeneProduct18125 (Entrez Gene)
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CrhGeneProduct12918 (Entrez Gene)
Gng13GeneProduct64337 (Entrez Gene)
Igfbp3GeneProduct16009 (Entrez Gene)
Gng11GeneProduct66066 (Entrez Gene)
Crhr1GeneProduct12921 (Entrez Gene)
Atf3GeneProduct11910 (Entrez Gene)
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FosGeneProduct14281 (Entrez Gene)
Grk4GeneProduct14772 (Entrez Gene)
OxtGeneProduct18429 (Entrez Gene)
CALM2GeneProduct
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PkibGeneProduct18768 (Entrez Gene)
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YwhagGeneProduct22628 (Entrez Gene)
Itpr2GeneProduct16439 (Entrez Gene)
SfnGeneProduct55948 (Entrez Gene)
DgkzGeneProduct104418 (Entrez Gene)
Gm2423GeneProduct100039786 (Entrez Gene)
Plcg1GeneProduct18803 (Entrez Gene)
Gja1GeneProduct14609 (Entrez Gene)
Plcb3GeneProduct18797 (Entrez Gene)
Il1bGeneProduct16176 (Entrez Gene)
Ryr3GeneProduct20192 (Entrez Gene)
Il6GeneProduct16193 (Entrez Gene)
Arrb1GeneProduct109689 (Entrez Gene)
GnaqGeneProduct14682 (Entrez Gene)
Cacnb3GeneProduct12297 (Entrez Gene)
Cxcr7GeneProduct12778 (Entrez Gene)
Lpar1GeneProduct14745 (Entrez Gene)
Gpr182GeneProduct11536 (Entrez Gene)
Acta1GeneProduct11459 (Entrez Gene)
JunGeneProduct16476 (Entrez Gene)
ActbGeneProduct11461 (Entrez Gene)
Pde4bGeneProduct18578 (Entrez Gene)
Actg1GeneProduct11465 (Entrez Gene)
Pde4dGeneProduct238871 (Entrez Gene)
Ramp2GeneProduct54409 (Entrez Gene)
Camk2dGeneProduct108058 (Entrez Gene)
Camk2gGeneProduct12325 (Entrez Gene)
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Ryr1GeneProduct20190 (Entrez Gene)
CALM1GeneProduct
Ryr2GeneProduct20191 (Entrez Gene)
Camk2bGeneProduct12323 (Entrez Gene)
ADPGeneProduct (CAS)
GabpaGeneProduct14390 (Entrez Gene)
Cyclic GMPMetaboliteHMDB01314 (HMDB)
Retrieved from "http://wikipathways.org/index.php/Pathway:WP385"
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