Ptf1a related regulatory pathway (Mus musculus)
By summarizing published study results together with ours, this network shows a complicated relationships between transcriptional factors, miRNAs and some functional genes which are correlated together to generate a whole sight in early mouse development centered around Ptf1a, although there are some hypothetical relationships and the distinct development of dorsal and ventral pancreas in very early stage is neglected.
View all 12 references
- Ghosh, B, Leach, S D; ''Interactions between hairy/enhancer of split-related proteins and the pancreatic transcription factor Ptf1-p48 modulate function of the PTF1 transcriptional complex; ''Biochem J, 2006 - PubMed
- Fujikura, J, Hosoda, K, Kawaguchi, Y, Noguchi, M, Iwakura, H, Odori, S, Mori, E, Tomita, T, Hirata, M, Ebihara, K, Masuzaki, H, Fukuda, A, Furuyama, K, Tanigaki, K, Yabe, D, Nakao, K; ''Rbp-j regulates expansion of pancreatic epithelial cells and their differentiation into exocrine cells during mouse development; ''Dev Dyn, 2007 - PubMed
- Wells, J M, Esni, F, Boivin, G P, Aronow, B J, Stuart, W, Combs, C, Sklenka, A, Leach, S D, Lowy, A M; ''Wnt/beta-catenin signaling is required for development of the exocrine pancreas; ''BMC Dev Biol, 2007 - PubMed
- Dong, P D, Provost, E, Leach, S D, Stainier, D Y; ''Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas; ''Genes Dev, 2008 - PubMed
View all 9...