TP53 network (Homo sapiens)

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Curation Tags

Description

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Ontology Tags

 

Bibliography

View all 6 references
  1. Dohn M, Zhang S, Chen X; ''p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes.; ''Oncogene, 2001 - PubMed
  2. Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dötsch V, Andrews NC, Caput D, McKeon F; ''p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.; ''Mol Cell, 1998 - PubMed
  3. Ishimoto O, Kawahara C, Enjo K, Obinata M, Nukiwa T, Ikawa S; ''Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73.; ''Cancer Res, 2002 - PubMed
  4. Shaul Y; ''c-Abl: activation and nuclear targets.; ''Cell Death Differ, 2000 - PubMed
  5. Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY, Lu H, Kharbanda S, Weichselbaum R, Kufe D; ''p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.; ''Nature, 1999 - PubMed
  6. Bunt J, de Haas TG, Hasselt NE, Zwijnenburg DA, Koster J, Versteeg R, Kool M; ''Regulation of Cell Cycle Genes and Induction of Senescence by Overexpression of OTX2 in Medulloblastoma Cell Lines.; ''Mol Cancer Res, 2010 - PubMed

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History

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CompareRevisionActionTimeUserComment
59109view22:22, 21 February 2013MaintBotUpdated Ensembl data source
48062view18:41, 1 May 2012KhanspersReplaced special characters
48060view18:14, 1 May 2012KhanspersPeriodical save, work in progress
45074view20:17, 6 October 2011KhanspersOntology Term : 'cancer' added !
45073view20:16, 6 October 2011KhanspersOntology Term : 'p53 signaling pathway' added !
41057view23:17, 1 March 2011MaintBotRemoved redundant pathway information and comments
39274view22:33, 9 November 2010AlexanderPicoModified categories
39273view22:32, 9 November 2010AlexanderPicoconnected line from SUMO-1 to TP53
39272view22:30, 9 November 2010AlexanderPicospecified xref systems, e.g., Entrez, UniProt or Ensembl
39264view11:17, 8 November 2010GlendaPeriodical save, work in progress
39263view10:56, 8 November 2010GlendaPeriodical save, work in progress
39262view10:36, 8 November 2010GlendaPeriodical save, work in progress
39261view09:54, 8 November 2010GlendaPeriodical save, work in progress
39260view09:43, 8 November 2010GlendaPeriodical save, work in progress
39205view07:57, 28 October 2010GlendaPeriodical save, work in progress
39204view07:47, 28 October 2010GlendaPeriodical save, work in progress
39203view07:10, 28 October 2010GlendaModified description
39202view05:03, 28 October 2010GlendaModified description
39197view14:05, 27 October 2010GlendaPeriodical save, work in progress
39196view13:49, 27 October 2010GlendaPeriodical save, work in progress
39195view13:38, 27 October 2010GlendaPeriodical save, work in progress
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39191view12:52, 27 October 2010GlendaPeriodical save, work in progress
39190view12:39, 27 October 2010GlendaPeriodical save, work in progress
39189view12:28, 27 October 2010GlendaPeriodical save, work in progress
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39186view11:57, 27 October 2010GlendaPeriodical save, work in progress
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39148view13:32, 22 October 2010GlendaPeriodical save, work in progress

External references

View all 29...

Name Type Database reference
TP73γProteinO15350
ATMGeneProductENSG00000149311
PMAIP1GeneProduct5366
ABL1GeneProduct25
TAp63βProteinQ9H3D4 (Uniprot/TrEMBL)
TP73ζProteinO15350
CDKN1AGeneProductENSG00000124762
BAXGeneProduct581 (Entrez Gene)
ΔNp63αProteinQ9H3D4
TP73βProteinO15350
GADD45AGeneProduct1647
ΔNp63βProteinQ9H3D4 (Uniprot/TrEMBL)
CDKN2AGeneProduct1029 (Entrez Gene)
TAp63αProteinQ9H3D4
TP73αProteinO15350
TP73δProteinO15350 (Uniprot/TrEMBL)
TP73εProteinO15350
TP53GeneProduct7157
ΔNp63γProteinQ9H3D4
TP73GeneProduct7161
MDM2GeneProductENSG00000135679 (Ensembl Human)
MYCGeneProduct4609
SUMO-1Protein7341
TAp63γProteinQ9H3D4 (Uniprot/TrEMBL)
BBC3GeneProduct27113
TP73 Delta Np73ProteinO15350
BOKGeneProduct666
TP63GeneProduct8626
IGFBP-3GeneProductHs.146732 (UniGene)
Retrieved from "http://wikipathways.org/index.php/Pathway:WP1742"
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