Physiological and Pathological Hypertrophy of the Heart (Homo sapiens)

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Bibliography

View all 15 references
  1. Molkentin JD; ''Calcineurin and beyond: cardiac hypertrophic signaling.; ''Circ Res, 2000 - PubMed
  2. MacLellan WR; ''Advances in the molecular mechanisms of heart failure.; ''Curr Opin Cardiol, 2000 - PubMed
  3. Jalili T, Takeishi Y, Walsh RA; ''Signal transduction during cardiac hypertrophy: the role of G alpha q, PLC beta I, and PKC.; ''Cardiovasc Res, 1999 - PubMed
  4. Wollert KC, Taga T, Saito M, Narazaki M, Kishimoto T, Glembotski CC, Vernallis AB, Heath JK, Pennica D, Wood WI, Chien KR; ''Cardiotrophin-1 activates a distinct form of cardiac muscle cell hypertrophy. Assembly of sarcomeric units in series VIA gp130/leukemia inhibitory factor receptor-dependent pathways.; ''J Biol Chem, 1996 - PubMed
  5. Wang Y; ''Signal transduction in cardiac hypertrophy--dissecting compensatory versus pathological pathways utilizing a transgenic approach.; ''Curr Opin Pharmacol, 2001 - PubMed
  6. Olson EN, Molkentin JD; ''Prevention of cardiac hypertrophy by calcineurin inhibition: hope or hype?; ''Circ Res, 1999 - PubMed
  7. Takeishi Y, Ping P, Bolli R, Kirkpatrick DL, Hoit BD, Walsh RA; ''Transgenic overexpression of constitutively active protein kinase C epsilon causes concentric cardiac hypertrophy.; ''Circ Res, 2000 - PubMed
  8. Clerk A, Sugden PH; ''Small guanine nucleotide-binding proteins and myocardial hypertrophy.; ''Circ Res, 2000 - PubMed
  9. Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN; ''A calcineurin-dependent transcriptional pathway for cardiac hypertrophy.; ''Cell, 1998 - PubMed
  10. Lim HW, Molkentin JD; ''Calcineurin and human heart failure.; ''Nat Med, 1999 - PubMed
  11. Hunter JJ, Chien KR; ''Signaling pathways for cardiac hypertrophy and failure.; ''N Engl J Med, 1999 - PubMed
  12. Wollert KC, Chien KR; ''Cardiotrophin-1 and the role of gp130-dependent signaling pathways in cardiac growth and development.; ''J Mol Med, 1997 - PubMed
  13. Wang Y, Su B, Sah VP, Brown JH, Han J, Chien KR; ''Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells.; ''J Biol Chem, 1998 - PubMed
  14. Bueno OF, De Windt LJ, Tymitz KM, Witt SA, Kimball TR, Klevitsky R, Hewett TE, Jones SP, Lefer DJ, Peng CF, Kitsis RN, Molkentin JD; ''The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice.; ''EMBO J, 2000 - PubMed
  15. Heineke J, Molkentin JD; ''Regulation of cardiac hypertrophy by intracellular signalling pathways.; ''Nat Rev Mol Cell Biol, 2006 - PubMed

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45248view18:35, 7 October 2011KhanspersOntology Term : 'heart disease' added !
41110view23:22, 1 March 2011MaintBotRemoved redundant pathway information and comments
39763view07:39, 17 January 2011AlexanderPicomore complete title
37536view13:21, 9 June 2010MLevelsSpecify description
37535view13:19, 9 June 2010MLevelsModified description
37279view07:30, 24 May 2010MLevelsID
37157view14:57, 18 May 2010MLevelsMoved Line
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37120view13:26, 17 May 2010MLevelsRemoved some of the added things, making a separate pathway for those.
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External references

View all 31...

Name Type Database reference
CTF1GeneProduct1489 (Entrez Gene)
LIFRGeneProduct3977 (Entrez Gene)
p38?GeneProduct1432 (Entrez Gene)
gp130GeneProduct3572 (Entrez Gene)
CalmodulinProtein801 (Entrez Gene)
STAT3GeneProduct6774 (Entrez Gene)
GATA-4GeneProduct2626 (Entrez Gene)
erkGeneProduct5594 (Entrez Gene)
PKCbGeneProduct5579 (Entrez Gene)
p38bGeneProduct5600 (Entrez Gene)
CalNAGeneProduct5530 (Entrez Gene)
PKCEGeneProduct5581 (Entrez Gene)
FOSGeneProduct2353 (Entrez Gene)
PAKGeneProduct
CalNBGeneProduct5532 (Entrez Gene)
Ang IIGeneProduct183 (Entrez Gene)
RhoAGeneProduct387 (Entrez Gene)
ET-1GeneProduct1906 (Entrez Gene)
p38aGeneProduct1432 (Entrez Gene)
Rac1GeneProduct5879 (Entrez Gene)
CalciumMetaboliteHMDB00464 (HMDB)
GqGeneProduct
CamKGeneProduct
RASGeneProduct
C-JUNGeneProduct3725 (Entrez Gene)
GiGeneProduct
NFAT3GeneProduct4776 (Entrez Gene)
MKK3GeneProduct5606 (Entrez Gene)
MEF-2GeneProduct50804 (Entrez Gene)
JNKGeneProduct5599 (Entrez Gene)
PEMetaboliteHMDB02182 (HMDB)
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